From a profile I wrote:
One of the possible side effects associated with use of tamoxifen citrate is the possible reduction of insulin-like growth factor levels. If these levels are reduced this could suppress the gains an individual can make slightly. However this reduction, if it actually exists, would not be overly significant with gains in muscle mass only being marginally reduced for the most part.
Another effect of use of tamoxifen citrate may be vision problems. Recently, there has been some information from researchers that indicates corneal, retinal and optic nerve abnormalities seen in patients using the drug could be related to its use (5). Anecdotally a small number of steroid users have reported that they have suffered from visual problems while using this drug as well. After discontinuation of the drug these symptoms seemingly dissipate. However there is simply not enough research on the subject to know whether permanent damage could occur. More research needs to be conducted.
Other than these concerns, there is little in the way that long-term use of tamoxifen citrate could cause damage to in the human body. It is seemingly safe in terms of possible effects to the body’s hormonal production, other than the one relating to insulin-like growth factor, and endocrine system (4). For the vast majority of users the compound is relatively side effect free and well tolerated.
