I personally take two in the morning (4:45 am) with a table spoon full of cottage cheese.....my stomach can't take it when its empty. Then two again about 10 or so and two more about 3.....that way I don't stay up all night
Yohombine...the Y in nYc needs to be taken on an empty stomach. Taking it with food defeats the purpose of using the yohombine hcl that is in it. Insulin blunts the effects of yohombine hcl so you get none of yohombine's advantages by takinng it this way.