<h1>Permapen</h1><p> (Penicillin G Benzathine) Injectable Suspension, a sterile antibacterial agent, is a
repository penicillin compound which provides blood levels for long periods following its
intramuscular injection. This property is the result of its extremely low solubility in water. Each
milliliter contains 600,000 units of penicillin G benzathine; 0.006 grams sodium citrate;
0.003 grams polyvinylpyrrolidone; 0.010 grams lecithin, and 0.003 grams sodium
carboxymethylcellulose in an aqueous suspension. Permapen also contains methylparaben 0.09%
and propylparaben 0.01% as preservatives.
Chemically, Permapen is 3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-l-azabicyclo [3.2.0]
heptane-2-carboxylic acid compound with N,N′-dibenzylethylenediamine (2:1) tetrahydrate. It is
prepared by the reaction of dibenzyl-tetrahydrate-ethylenediamine with 2 molecules of penicillin
G.</p>
repository penicillin compound which provides blood levels for long periods following its
intramuscular injection. This property is the result of its extremely low solubility in water. Each
milliliter contains 600,000 units of penicillin G benzathine; 0.006 grams sodium citrate;
0.003 grams polyvinylpyrrolidone; 0.010 grams lecithin, and 0.003 grams sodium
carboxymethylcellulose in an aqueous suspension. Permapen also contains methylparaben 0.09%
and propylparaben 0.01% as preservatives.
Chemically, Permapen is 3,3-dimethyl-7-oxo-6-(2-phenylacetamido)-4-thia-l-azabicyclo [3.2.0]
heptane-2-carboxylic acid compound with N,N′-dibenzylethylenediamine (2:1) tetrahydrate. It is
prepared by the reaction of dibenzyl-tetrahydrate-ethylenediamine with 2 molecules of penicillin
G.</p>