premature ejaculation developed, ephedrine, vitamin b6, histamine

[lexy123]

Ok so Im not sure if this is the right area to post this thread but here it goes,

I have recently started a thread on my PRE PCT-PCT recovery using supplements to kick start my natty test which has actually worked amazingly, so chuffed with it...but....as a result....I now have PE (premature ejaculation)....now this is funny one with me, before I was circumcised at 17 I never had the problem, was given tramadol after the surgery, loved it, then I finished the tramadol and BOOOOOM...PE...I then went on tramadol alot using my own and others to treat my PE.....this went on for yeeaarsss...until this year I decided I wanted to be off it and do it myself.....I ended a 9 yr relationship and now have a new gf who is MUCH hotter and I mean...insane hot...shes a model :/ i thought oh crap....anyways I didnt have any issues at all....literally she was telling me to finish....great...anyways did an AAS cycle (my 5th cycle) of the usual 750mg test e and dbol, finished, had raging bad low libido and ed issues, solved that (see my other thread for info on that) but as a result of these supps I used...PE returned...now when I say I have PE...I mean after penetration, she gives the best head I have ever had and I manage fine with that, but upon penetration your talking 2-3 mins and I need to jizz....

Now I have researched the supps I have put my self on to cure my low libido and ED..see below:
MACA
GINSENG
GOJJII BERRY
HGW
DAMIANA CIGS
VIT B6 +B12
GOLDEN ROOT-before jiggy
tribulus (goes without saying)
AAKG-before jiggy

now these worked...AMAZINGLY for pre-pct/pct low libido ED issues and my mood is amazing now, I feel sane and human again

I will also ADD that upon finishing my bulk cycle (put abit of fat on naturally) I decided to add Ephedrine to help move some of the chubb I added with the huge amounts of muscle gain....now I know Eph has been known to cause ED issues....I have cycled ephedrine for years with no issues, but at the time I had ED issues and low libido so dropped it just in case it wasnt helping

Now what I did was when the above supps took effect and gained my erections and libido back and confidence, I continued the ephedrine at about 60-70mg a day split up.........

At some point my PE developed....

This has opened research to me over the 2 particular points I think I noticed the change with PE...

this was the addition of ephedrine and vitamin b6

I started mega dosing b6 at 500-600mg a day as this was supposed to help with libido (which it did!) and it was with this I noticed the PE during sex

but...I was also on ephedrine....

Here is my issue, I dont know which one, if not both, have caused it....

Upon research I found this:

VIT B6 encourages histamine production through conversion.....high levels of histamine have been shown to be a contributory factor in PE

Ephedrine- is known to inflame the prostate which causes PE

So here is my plan...to which I will follow up the result for those interested!

Vit b6-stop it for a few days....I have also bought some loratadine and HTP-5 as these are known to help combat high histamine levels (10mg of loratadine as it can kill wood...which is a concern for me considering my epic recovery of ED and low libido.......) 10mg an hour or so before jiggy....and take 300-400mg of HTP 5 an hour or so before too....I dont want to over kill it though...so I am gonna have to play with doses and combining them both...maybe I dont need both...I will have to see

Ephedrine-Stopped today and leaving it out for good for now

I do have a few tramadol tabs left which I will keep just incase to not alert the fiance to a recurring PE issues....so in other words break up the short sex with some of the usual long amazing sex we have....like a little vacation if you like for us both......

Another note is we went camping over the weekend and I hadnt taken ephedrine for like 2 days (As it makes me irritable and wanted to enjoy the weekend with her) and I was horny as absolute hell......we had jiggy...it was amazing...she told me to finish after 45 odd mins and I did with a great orgasm....like old times when I wasnt on tramadol or b6/eph.....(during my AAS cycle and just after before the ed and low libido)....but I had also taken 100mg of tramadol (I have a huge tolerance to it after years of taking it so 100mg isnt much for me at all)

The issue with this is, was it the tramadol that prevented the PE....or was it that I hadnt taken any ephedrine and so didnt have an inflamed prostate??? or both??

Im hoping it had nothing to do with the tramadol....and was the absence of eph that resulted in the control of my pe.....

The problem I have is Vit b6 has had a huge impact on my mental well being and libido! I love mega dosing it! (Im aware long term is toxic, I dont intend to do it long term, I have only done it for 12 days so far) so Im worried if I drop it to help lower histamine levels (if thats what the pe issue is!) that my libido and mood goes with it too!!!

So with my plan as above...I will keep note of how I get on, now I have dropped the B6 and Eph and no taking tramadol still, I will start the HTP-5 and loratadine when it arrives hopefully tomorrow, I may try it on tonight with the fiance if shes game and see how I get on now I have no ephedrine in my system, this way I will know it was the eph causing inflamed prostate and I can continue the B6 and not have to use the HTP-5 or loratadine!!! thats my ideal outcome!

So tonight...no eph in my system....reduced prostate (if after one day it will have reduced?? maybe a little to soon?) I will give it a go

Tomorrow....take HTP-5 and 10mg of loratadine before jiggy no vit b6 still....see what happens

then I will update you guys with the result!

 

[tbonexl]

Your like a walking chemistry set! Too much going on with you. Get some Cialis and hit it again. Winner winner, chicken dinner...

 

[lexy123]

is cialis going to contribute to solving the PE?

 

[tbonexl]

You'll be able to fuck more so who cares how much you get off? Your chic probably gets off multiple times (I hope)...

 

[halfwit]

I'm sorry, but I've never heard of half these side effects you're proposing. Ephedrine is a beta agonist, which should have the opposite impact in fact, by causing a release of epinephrine - halting histamine reactions.

Of all the items listed in your post, the one that most likely is causing issues would be the tramadol. Are you on long-term pain management, or has this been for recreational purposes? Pain killers have a profound effect on the brain, which can seriously mess with your dopamine uptake and even cause desensitization to the "reward hormone". I have a sneaking suspicion that this is the root of your problems as most of the sides you're experiencing could possibly be withdrawals from the drug.

As far as PE is concerned, are you masturbating frequently? We men can easily train ourselves to climax quickly as well... that's kind of the goal when rubbing one out. If this is the case, I'd try holding off on beating your meat for awhile and focusing on her.

I agree, cialis will help you make the transition off all the stuff you're taking - so you can still take care of business without as much worry. I strongly recommend you get a blood test too; never hurts to get an idea as to what is REALLY going on, not just guessing and throwing more stuff into the mix.

My .02c

 

[Roush]

I think halfwhit has it right

If I take a tramadol to take the edge off of my lower back pain,, and I end up having to "perform" it takes forever to finish one off for her.
Coincidentally I just took one-- guess I'll be getting a cardio session in today after all

OP I'm assuming you didn't have Pe issues while taking tramadol

 

[juced_porkchop]

beat it before sex and take CIA or V to keep it up. for now. consider cutting out some supps. seems like alot.

 

[lexy123]

Hey guys thanks for replies,

So Ephedrine, didnt say it raised histamine! Problem with eph is it has been shown to enlarge prostate! Which increases some form of vibration to the penis thus causing PE, a simple google provides a mass result of findings on this!

As for beating one out and masturbating, my habits=I didnt really masturbate much as I was getting it every night until we both started new jobs and now its every 2-3 nights except weekends, my "habbits" arent hasty either, I dont beat to finish as quick as I can, I have always practiced the whole, beat till you nearly finish then stop, then start etc for about 15 odd mins, but like I said,before starting on vit D and ephedrine, I didnt have PE!! so none of this mattered before then!

As for beating one out before sex, I have tried that, it used to work, now it doesnt!!!! I beat it twice during the day, had sex later that night, still same problem, like i said, its just since i started taking vit d and eph....and its not insanely bad PE....like i said, its just penetrative and its minor compared to other cases, but it sucks going from being told when to finish, to just doing it!

As for cutting supps out, its hard, because im PCT....and I would rather have a sex drive and erection and have PE than none of the above! hence the walking chemistry set

BUT I have dropped the vit b6 and b12 and ECA stack!

Also regarding the tramadol, I had been off it 6 weeks and still no PE! I had tapered down purposely to just 50mg at night until I came off, then had 6-7 weeks with nothing and no PE...until I started the vit b6 and eph......interesting theory but I dont think its the case here because I was nearly off them 2 months!

 

[halfwit]

Hey guys thanks for replies,

So Ephedrine, didnt say it raised histamine! Problem with eph is it has been shown to enlarge prostate! Which increases some form of vibration to the penis thus causing PE, a simple google provides a mass result of findings on this!

As for beating one out and masturbating, my habits=I didnt really masturbate much as I was getting it every night until we both started new jobs and now its every 2-3 nights except weekends, my "habbits" arent hasty either, I dont beat to finish as quick as I can, I have always practiced the whole, beat till you nearly finish then stop, then start etc for about 15 odd mins, but like I said,before starting on vit D and ephedrine, I didnt have PE!! so none of this mattered before then!

As for beating one out before sex, I have tried that, it used to work, now it doesnt!!!! I beat it twice during the day, had sex later that night, still same problem, like i said, its just since i started taking vit d and eph....and its not insanely bad PE....like i said, its just penetrative and its minor compared to other cases, but it sucks going from being told when to finish, to just doing it!

As for cutting supps out, its hard, because im PCT....and I would rather have a sex drive and erection and have PE than none of the above! hence the walking chemistry set

BUT I have dropped the vit b6 and b12 and ECA stack!

Also regarding the tramadol, I had been off it 6 weeks and still no PE! I had tapered down purposely to just 50mg at night until I came off, then had 6-7 weeks with nothing and no PE...until I started the vit b6 and eph......interesting theory but I dont think its the case here because I was nearly off them 2 months!

Can you please link the studies showing an impact on the prostate from ephedrine or any ephedra alkaloid? I've done a great deal of research on this compound and have only seen this reported in forums without any real scientific backing. Ephedra/ephedrine causes your adrenal glands to release epinephrine, which I have not seen any papers showing such a link. The closest I've seen is a contraindication when a person has prostatitis, but that's more of a caution as kidney stones may occur (usually due to poor water intake).

I'm not saying you're wrong, but I'd like to read this as I'm always interested in learning more about the drugs in the realm of personal enhancement.

If you're in PCT, you should be on clomid and nolvadex. I honestly think that you're just throwing too many things at this when the problem may be as simple as elevated prolactin or estradiol, combined with lower testosterone. A blood panel will help to rule these out for sure.

Please don't take my posts as disrespect, I don't mean any - I just have a habit of tackling these things from an analytical standpoint.

 

[Mprtz]

Drugs.com does warn against ephedrine with an enlarged prostate, and WebMD lists "difficult or painful urination" as a side effect of ephedrine. Not quite the study you are looking for, but probably more than bro-science.

Anecdotally, I definitely felt an effect on my prostate when taking ECA 20 years ago or so... cramping feeling while urinating, etc.

 

[FormerFatty]

Drugs.com does warn against ephedrine with an enlarged prostate, and WebMD lists "difficult or painful urination" as a side effect of ephedrine. Not quite the study you are looking for, but probably more than bro-science.

Anecdotally, I definitely felt an effect on my prostate when taking ECA 20 years ago or so... cramping feeling while urinating, etc.

This is probably the answer, with the Stims you are taking your prostate is becoming inflamed which is reducing the strength of the muscle. I have had this side effect before when running a few of the items you are taking. Usually it starts by have a weaker orgasm, with your fluids not coming out with that 1 foot shot strength. Then to a dribble. Take a break and lower your doses down for a bit. If you notice the symptoms are gone that is your culprit.

 

[lexy123]

theres that many instances I have found just from a simple google search I wouldnt know where to start lol, also backed up by searching forums on peoples first hand exp with eph and PE/enlarged prostate, I mean I have used it for years and never had any issues tbh but then again I was on tramadol so as far as I know it could have been enlarging it but not having the PE issues with it because of the tramadol

Note as well: I havnt used eph in 3 days and had jiggy last night after taking 300mg of HTP-5....I couldnt finish...I had to fake it......one extreme to the next but id rather fake it once than have PE! just a case of adjusting the dose I think and I should be balanced and happy!

 

[FormerFatty]

I have been in a similar situation where I had to fake it. Has happened a few times. You think guys get an ego destruction when the can't get their partner off. Women take a real hist since it is pretty much a given that a guy is going to get off. When it doesn't happen it women are hit like a ton of bricks.

 

[Spid3rAlex]

Think Rosie O'donnel. Works for me every time. Almost results in limpage...almost. Definitely solves the PE problem though!

 

[lexy123]

Ok so an update!

5-HTP seems to be working pretty well----one night I felt super sensitive and wanted to blow instantly, managed to control it with a few mins of going slow and steady then boom, had amazing sex and finished when I was told to happy days, also taking loratadine @ 0.5mg and 100mg viagra or a golden root, just to ward off any mid PCT ED issues popping up and potentially crushing my confidence and libido!

AS for current supps now to support libido and ed and pe here is as listed (libido still strong, good big erections! happy!)
-Maca dropped down from 4000mg to 3000mg ed
-trib-5 days on 2 off (notice on 2 days off im super horny!)
-HGW (ramping this down as I notice im less horny when i take it!)
-vitamin b6+12 (I have experimented letting it clear my system in terms of libido and PE....I notice when I let it clear, my libido is SLIGHTLY lower....but also no PE!)...I am now dropping this unless my libido hits rock bottom again then I will start back on 600mg ed of b6
-Melanotan 2....tried this for a week nearly....crap....just flushes my face...no random boners, no increased sex drive...total crap!...dropped for good
-cordyceps-useless.....unless its these that have added to my increased "load" which the girl loves! since i started them I have noticed an increase on sperm vol...but wont be using them again not worth the cash!
-gojjii berry---still using this just because I have it and may aswell finish it....dont reckon it makes much difference though!

I have noticed that with the stack I STARTED (as above in my initial post) my erections are larger and thicker....definite increase in size from something.....so now I am dropping out a good few supps will keep an eye on it.....if things change slowly start to add back in thing I took out to see what changes!!!

 

[CYP11A1]

I'll admit, with all that's going on I didn't read all the details. But, how can you tell what's doing what with all that going on? Starting, stopping, interacting drugs?