cybrsage
New member
Hello everyone! I am starting a log, I enjoy doing logs and, as everyone who knows me already knows, I am quick to say when a product does not work as advertised. I am predispositioned to believe the SarmsSearch ******** will work as they say, since I have run both GW50 and MK677 already and they did exactly what they said they were. While running MK677, IGF numbers from my first MK677 run ever went up a lot. I am not sure if that is because I am a on TRT due to low test levels naturally, or whatnot, but it was a massive increase. I searched all over and cannot find my results! They increased from 99 (I think) to exactly 284. I have that blood work result:
IGF-1- Insulin-Like Growth Factor I - 284 HIGH - 67-205 ng/mL
I also love GW50 for the endurance enhancement effect. I always take it at a slightly higher dose than most people do, 30mg instead of 20mg, because testing showed me that is my best bang for the buck point.
The new product I am adding, Tesofensine, is supposed to help greatly reduce fat. Here is a little bit of info on it:
Under development by NeuroSearch, a Danish pharmaceutical company, tesofensine is a serotonin-noradrenaline-dopamine reuptake inhibitor. It was originally in development for the treatment of neurological disorders such as Parkinson’s disease (PD) and Alzheimer’s disease (AD). It failed miserably at doing anything for PD and AD, but the scientists noticed that everyone who used Tesofensine lost weight - a LOT of weight. So they reclassified the drug and started trials all ove again. Yes, they had to start at the beginning again even though they alredy did some human trials, but that is because they changed the purpose of the drug.
They found that people said they felt satiated sooner while eating, and felt satiated longer after eating. There is more to it than hunger control, though. The studies found that energy expendiature was increased as well; the basal metabolic rate went up. What about side effects? Great question. There are none. Well, not quite true, there is one. Heart rate increased by about 7bps at about 3 months of use but did not increase any more after that. It also had the same side effects as the plecebo had - dry mouth, headaches, etc.
161 (79%) participants completed a 24 week study. The mean weight loss produced by diet and placebo was 2.0% (SE 0.60). Tesofensine 0.25 mg, 0.5 mg, and 1.0 mg and diet induced a mean weight loss of 4.5% (0.87), 9.2% (0.91), and 10.6% (0.84), respectively, greater than diet and placebo (p<0.0001). After 24 weeks, tesofensine 0.25 mg and 0.5 mg showed no significant increases in systolic or diastolic blood pressure compared with placebo, whereas heart rate was increased by 7.4 beats per min in the tesofensine 0.5 mg group (p=0.0001).
References
Tesofensine Anti-Obesity Medication - Drug Development Technology
https://www.nature.com/articles/npp201016
https://www.ncbi.nlm.nih.gov/pubmed/18950853?dopt=Abstract&holding=npg
So there is the skinny on tesofensine. An accidental discovery poised to help people lose fat without any side effects.
Picture Goodness
Some Stats on me:
Height: 5'9" (this will not change - I hope!)
Weight: 202lbs
Body Fat Percent (using the Jackson/Pollock 3 Caliper Method): 16.5%
Stomach (belly button): 38"
Waist (pants line): 37.5"
I expected to be fatter, percentage wise. While I cannot say the percentage of body fat is correct, I am able to get the same number (very close to it at least) repeatedly, so it is good to show changes if nothing else.
Do you all want body pictures as well? I can take some if you like.
I will be using the following dosing:
Tesofensine: 1mg per day in one dose, 1 hour prior to working out
GW50: 30mg per day in one dose, 1 hour prior to working out
MK677: 25mg mg per day in one dose, 1 hour prior to bed (to help with the potential lethargy - might as well sleep the lethargy away!)
I will be doing a four day split set at the gym. Here is my proposed workout plan:
Day 1: Lower Body - 3 Sets of 6 – 12 Reps
1. Deadlifts
2. Cable Kick-Backs
3. Nordic Ham Curls
4. Leg Curl
5. Hyperextension (glute-focused)
Day 2: Upper Body - 3 Sets of 6 – 12 Reps
1. Incline Dumbbell Press
2. Push Up
3. Pec Deck Fly (Chest Machine)
4. Seated Dumbbell Press
5. Side Lateral Raise (Dumbell)
6. Overhead EZ Bar Tricep Extension
Day 3: Lower Body - 3 Sets of 6 – 12 Reps
1. Dumbell Squat
2. Dumbbell Lunge
3. Leg Press
4. Leg Extension
5. (Seated) Seated Calf Raise
Day 4: Upper Body - 3 Sets of 6 – 12 Reps
1. Bent Over Row
2. Seated Cable Row
3. Lat Pull Down
4. Standing Cable Reverse Fly
5. Dumbbell Curl
6. Reverse Dumbbell Curl
I will update every day or every other day.
NOTE: This entire log is fictional in nature. SARMs are not for human consumption, so any reference to human consumption is used as a representation as to potential effects if it were to actually be consumed by a human. No human will consume any SARM during the entirety of this log. SARMs are for laboratory animals only and have not been deemed safe by any US Government body.
IGF-1- Insulin-Like Growth Factor I - 284 HIGH - 67-205 ng/mL
I also love GW50 for the endurance enhancement effect. I always take it at a slightly higher dose than most people do, 30mg instead of 20mg, because testing showed me that is my best bang for the buck point.
The new product I am adding, Tesofensine, is supposed to help greatly reduce fat. Here is a little bit of info on it:
Under development by NeuroSearch, a Danish pharmaceutical company, tesofensine is a serotonin-noradrenaline-dopamine reuptake inhibitor. It was originally in development for the treatment of neurological disorders such as Parkinson’s disease (PD) and Alzheimer’s disease (AD). It failed miserably at doing anything for PD and AD, but the scientists noticed that everyone who used Tesofensine lost weight - a LOT of weight. So they reclassified the drug and started trials all ove again. Yes, they had to start at the beginning again even though they alredy did some human trials, but that is because they changed the purpose of the drug.
They found that people said they felt satiated sooner while eating, and felt satiated longer after eating. There is more to it than hunger control, though. The studies found that energy expendiature was increased as well; the basal metabolic rate went up. What about side effects? Great question. There are none. Well, not quite true, there is one. Heart rate increased by about 7bps at about 3 months of use but did not increase any more after that. It also had the same side effects as the plecebo had - dry mouth, headaches, etc.
161 (79%) participants completed a 24 week study. The mean weight loss produced by diet and placebo was 2.0% (SE 0.60). Tesofensine 0.25 mg, 0.5 mg, and 1.0 mg and diet induced a mean weight loss of 4.5% (0.87), 9.2% (0.91), and 10.6% (0.84), respectively, greater than diet and placebo (p<0.0001). After 24 weeks, tesofensine 0.25 mg and 0.5 mg showed no significant increases in systolic or diastolic blood pressure compared with placebo, whereas heart rate was increased by 7.4 beats per min in the tesofensine 0.5 mg group (p=0.0001).
References
Tesofensine Anti-Obesity Medication - Drug Development Technology
https://www.nature.com/articles/npp201016
https://www.ncbi.nlm.nih.gov/pubmed/18950853?dopt=Abstract&holding=npg
So there is the skinny on tesofensine. An accidental discovery poised to help people lose fat without any side effects.
Picture Goodness
Some Stats on me:
Height: 5'9" (this will not change - I hope!)
Weight: 202lbs
Body Fat Percent (using the Jackson/Pollock 3 Caliper Method): 16.5%
Stomach (belly button): 38"
Waist (pants line): 37.5"
I expected to be fatter, percentage wise. While I cannot say the percentage of body fat is correct, I am able to get the same number (very close to it at least) repeatedly, so it is good to show changes if nothing else.
Do you all want body pictures as well? I can take some if you like.
I will be using the following dosing:
Tesofensine: 1mg per day in one dose, 1 hour prior to working out
GW50: 30mg per day in one dose, 1 hour prior to working out
MK677: 25mg mg per day in one dose, 1 hour prior to bed (to help with the potential lethargy - might as well sleep the lethargy away!)
I will be doing a four day split set at the gym. Here is my proposed workout plan:
Day 1: Lower Body - 3 Sets of 6 – 12 Reps
1. Deadlifts
2. Cable Kick-Backs
3. Nordic Ham Curls
4. Leg Curl
5. Hyperextension (glute-focused)
Day 2: Upper Body - 3 Sets of 6 – 12 Reps
1. Incline Dumbbell Press
2. Push Up
3. Pec Deck Fly (Chest Machine)
4. Seated Dumbbell Press
5. Side Lateral Raise (Dumbell)
6. Overhead EZ Bar Tricep Extension
Day 3: Lower Body - 3 Sets of 6 – 12 Reps
1. Dumbell Squat
2. Dumbbell Lunge
3. Leg Press
4. Leg Extension
5. (Seated) Seated Calf Raise
Day 4: Upper Body - 3 Sets of 6 – 12 Reps
1. Bent Over Row
2. Seated Cable Row
3. Lat Pull Down
4. Standing Cable Reverse Fly
5. Dumbbell Curl
6. Reverse Dumbbell Curl
I will update every day or every other day.
NOTE: This entire log is fictional in nature. SARMs are not for human consumption, so any reference to human consumption is used as a representation as to potential effects if it were to actually be consumed by a human. No human will consume any SARM during the entirety of this log. SARMs are for laboratory animals only and have not been deemed safe by any US Government body.
