Being on testosterone replacement therapy (TRT) and your receptors

ScottyB28

New member
Being on TRT and your receptors

Wouldn't your receptors become use to the TRT? I been thinking about this, anyone know?
 
No such thing. It's an old school idea that receptors down regulate while cycling or doing TRT. What's actually happening to make people think this is a rise in SHBG. SHBG binds with T and lowers your Free T. In the past this made people think they were saturating (or whatever) their receptors. If you combat SHBG to a lower level with Proviron or a few other things, you get more bang for your buck with a rise in Free T.
 
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