I try to eat as much natural and organic as possible; yeah, I know that's not always possible, and can be too restrictive, but if I shoot for that then I'm going to do better in the long run, even if I sometimes fall short.
Minimal junk food! That stuff is loaded w/ trans fatty acids and refined carbs; in my mind, this is a much worse combo than saturated fats, for the most part.
This has become more and more important to me with age, recognizing that vascular disease and Type II diabetes are long term disease states w/ a protracted latency period. In other words, it's happening now, bro!
RoadHouse and DrVJ have it right. The calorie dense stuff is easy with good fats.