Stanozolol (Winstrol-V tm) and poor appetite with renal failure
Question: Dr. Richards,
Princess is a 16-year old Pom weighing in at 11 lbs. She is somewhere in
the end stage of kidney failure.
Question 1: She is given a weekly injection of 25 mg. of winstrol. At
what level is this dosage? And is one of the side effects heightened activity?
Princess kept me awake for a goodly portion of last night when her constant
rearranging of her blankets and pillows. What are some of the potentially
serious side effects of this drug?
Question 2: Princess currently receives 250 ml. daily of LRS. Would
upping the volume help to improve her appetite? Inappetance continues to be a
major problem.
Tony
Answer: Tony-
The recommended dosage of stanozolol (Winstrol-V tm) for small dogs by
injection is 25mg once a week. No dose range is suggested. For large dogs
it is recommended that Winstrol-V be given at a dose rate of 50mg once a
week by injection. It is available in an oral form, as well. When using
the oral tablets the dose for small dogs is 1 to 2mg per dog per day and
for large dogs it is 2 to 4mg per dog, per day. There is surprisingly
little information on the effects and side effects of stanozolol in the
veterinary literature considering that it has been around a long time. In
cats there are reported cases of liver damage that appear to be related to
use of the medication. In dogs the only side effects that are reported are
"androgenic effects", which might include increased aggression, increased
activity, weight gain and mood alterations. We do not use this medication
in our practice so I do not have much personal familiarity with it.
Increasing the fluid dosage will only increase Princess' appetite if she is
dehydrated or uremic (has toxins in the blood stream that should be removed
by the kidneys but that is not happening). A poor appetite may very well
be due to the presence of either of these conditions, though. If so,
increasing the fluid dosage might help with the situation.
Mike Richards, DVM
2/27/2001