My Story..........

[Bullseye Forever]

well i got my estrogen blood test back just now,and it has really dropped!!! on April 20th the level was 126.5pg/ml on the scale of 5-66pg/ml and today May 6th my level is 12.8pg/ml on the scale of 5-66pg/ml.....the aromasin done its job at 25mg/day........thats why im feeling much better,Det,should i drop the dose of the aromasin down to 12.5mg ED?And now im gonna pin 2 times a week to keep my test levels in check

 

[cjw2021]

Personally I immediately know if my e2 gets too low because my joints start to hurt. I'd just go by symptoms and see how you feel. Since the half life of aromasin is 27 hours according to google, you could try taking that dose every other day before it builds up in your blood and crashes your estrogen which it most likely will do if you take it at that dose everyday. I have no personal experience with aromasin though.

 

[BBE]

i dont think that is necessary, i would rather double dose the aromasin and then taper back. or just use letro for good.

letro might be a bit harsh on the lipids to use for good, no?

 

[THE-DET-OAK]

they all effect your lipids, even aromasin, some more than others, and in differnt ways. i wouldnt worry about until you got to half the dose that studies have found that it causes an issue.

for instance, arimadex effects total triglycerides (in women) at 1mg ED. keep in mind these studies were for like 24 months. it was reported to have an impact that barely increased your chance of CVD.

the other problem is that AI's, more than other subtances, have quite a different impact in men than they do in women. so dont get me wrong i wouldnt want to run adex @ say 3mg a week for super long periods. if i had to for 6 months I wouldnt worry about it. but there is no reason to run such a high amount for so long, cause you can usually find other ways to control estrogen so that you dont need that much. Like eating anti-estrogenic foods, lowering BF%, staying away from foods that have high estrogen response, increasing injection frequency...........the are more but cant remember right now.

that make sense?

now with letro everyone says how harsh it is. and it will effect lipids, but studies show this @ 2.5mg ED in women. in most cases .625mg E3D is plenty. I think cholesterol effects are dose and duration dependent. just as is the % of aromatase enzymes that are affected.

 

[THE-DET-OAK]

here is a study on adex in elderly men with mild hypo. there were no marginal effects on lipids. the dose was 1mg ED and 1mg 2x a week. this was a 12 week course though. in truth we do not know what the long term effects of any of these AI's in men. so we have to pull what we can from the studies on women. we may find out 1 day that they are fine though, who knows.

Effect of aromatase inhibition on lipids and inflammatory markers of cardiovascular disease in elderly men with low testosterone levels - Dougherty - 2005 - Clinical Endocrinology - Wiley Online Library

 

[THE-DET-OAK]

here is a good article that explains foods and materials with estrogenic and anti-estrogenic properties.

Anti-Estrogen/Warrior Diet

 

[THE-DET-OAK]

I will just answer the question now cause I know its coming:

Q: Can I use and Aromatase inhibitor (AI) to treat hypogonadism?

A: NO

"From these data, we conclude that in the human male, estrogen has dual sites of negative feedback, acting at the hypothalamus to decrease GnRH pulse frequency and at the pituitary to decrease responsiveness to GnRH."

Aromatase Inhibition in the Human Male Reveals a Hypothalamic Site of Estrogen Feedback -- Hayes et al. 85 (9): 3027 -- Journal of Clinical Endocrinology & Metabolism

in addition long-term treatment will have a negative impact on bone mineral density.

 

[THE-DET-OAK]

you could try taking that dose every other day before it builds up in your blood and crashes your estrogen which it most likely will do if you take it at that dose everyday. I have no personal experience with aromasin though.

after reading this you may change your mind, the science behind aromasin supports the opposite. it is very hard to erase all estrogen with aromasin. I tell guys quite often i dont know why people think aromasin is so strong, that is not what I have experienced. i think the purported rumor that aromasin will drop your estro 80% is because of the studies on women, the following is how it acts on men.

http://jcem.endojournals.org/cgi/reprint/88/12/5951.pdf