The American Red Cross performs laboratory tests for multiple infectious disease markers on every unit of donated blood. Tests are upgraded or replaced with more sensitive technologies as these become available. These tests include:
Chagas disease (T. cruzi)
Hepatitis B virus (HBV)
Hepatitis C virus (HCV 3.0)
Human Immunodeficiency viruses, Types 1 and 2 (HIV 1,2)
Human T-Lymphotropic virus (HTLV-I/II)
Syphilis (Treponema pallidum)
West Nile virus (WNV)
In addition to these tests, the Red Cross tests every unit to identify the donor’s blood group (O, A, B or AB) and Rh type, and screens for atypical or unusual red cell antibodies. Screening for antibodies to cytomegalovirus (CMV) is also available.