I have a question. Started testosterone replacement therapy (TRT) about 10 weeks ago. Start test level was 277, last lab read almost 800. However, started having estradiol side effects and had that checked last week and was at 127 (extremely high). Doc started Aromatase inhibitor (AI) Arimidex at .5 on day of injection and three days after injection. I take 200ml test injection weekly. I don't feel the Aromatase inhibitor (AI) is enough but just started it last week. I also have 250ml Human Chorionic Gonadotropin (HCG) two days prior and the day before (x2 weekly) to test injection. I guess my question is....is this the best level and way to take an Aromatase inhibitor (AI) with my estradiol out of control like that?
TRT, HCG, AI, and estradiol
- Thread starter judogi24
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Mprtz
New member
Can't weigh in as an expert, but am similar time into testosterone replacement therapy (TRT) at the same dose. Initial level 243, last 860. My estradiol was also a little high at 62 (though I have no symptoms) with .5 Arimidex the day after injection. Am also doing Human Chorionic Gonadotropin (HCG) 500mg day 3 and 5 after injection.
I am going to 2x weekly injections of 100mg with .5 mg Arimidex the day after each injection. Doc has also suggested progesterone to help with estradiol balancing. Seems to me that your plan is reasonable and exactly what I would be changing except that I've decided also to go 2x weekly instead.
I am going to 2x weekly injections of 100mg with .5 mg Arimidex the day after each injection. Doc has also suggested progesterone to help with estradiol balancing. Seems to me that your plan is reasonable and exactly what I would be changing except that I've decided also to go 2x weekly instead.
Megatron28
Moderator
As said, split the Test dose. And that is most likely plenty of Aromatase inhibitor (AI). Arimidex is pretty powerful stuff and it doesn't take much. That actually might be too much. You may be better off going with .25mg twice per week. Make sure you keep monitoring your estradiol until you get things dialed in.
Mprtz
New member
leaking breast? do you mean prolactin? or do you have a reference? The progesterone is an oral - 50mg daily. I've done a little research and it seems to make sense, plus is supposed to have some prostate protective properties. Only downside I have read is liver.
Mprtz
New member
I've taken the oral progesterone for a few days now and don't feel any side effects. Not sure where you put the cream if you're a guy...
Some things I have read:
Males make progesterone. They need it to make their testosterone and for the adrenal glands to make cortisone. Males synthesize progesterone in amounts less than women do but it is still vital. Men with BPH (benign prostatic hypertrophy) and other male related issues may notice relief with progesterone cream. Progesterone does not produce feminizing characteristics. Progesterone is an 5-alpha reductase inhibitor - it helps prevent the conversion of testosterone into DHT.
Progesterone may also help men with complexion and increased energy. Progesterone balances the estrogens that build in a man's body. Furthermore, it may be important in the prevention and/or treatment of prostatism and prostate cancer.
There are progesterone receptor sites all over the body for men and women. For men, it also seems to be important as one of the regulatory mechanisms in the production of sperm.
Dr Normal Shealy recommends that men who are entering the andropause (the male
menopause) can use natural progesterone cream on the scrotal area to find improvement in mood and libido.
What does this mean?
As a man ages more testosterone is converted to DHT, which has been linked with male pattern baldness and prostate enlargement.
By supplementing with progesterone you are:
• Helping to prevent excessive conversion of testosterone to DHT.
• Offsetting falling progesterone levels.
• Offsetting any increases in oestrogen, which also tends to happen. (The fall in testosterone and an increase of conversion to DHT causes an increase in oestrogen effect to one that is equivalent or greater than post menopausal women’s.
Suggested Use: 1/8th teaspoon per day.
Notes: Take weekends off. That is dose Monday to Friday. Rotate areas of application, use: scrotum, face and neck, inside of arms, backs of knees and palms of hands.
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