IMO, transdermals dont do much other than boost libido and general mood while on.........I would run SDMZ for 4 weeks at 2/day alongside the trans.....I would just plan a 4 week cycle for both and do a proper post cycle therapy (pct). SDMZ will shut U down over a 4 week period and the lethargy is pretty heavy at the 3rd week / 4th week period..........