hhajdo
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Posted by Nandi12...
Ann Pharmacother 2002 Jul-Aug;36(7-8):1178-9
Possible zoophilia associated with dopaminergic therapy in Parkinson disease.
Jimenez-Jimenez FJ, Sayed Y, Garcia-Soldevilla MA, Barcenilla B.
"A 74-year-old patient with PD was treated with controlled-release carbidopa/levodopa 25/100 mg 3 times daily and bromocriptine 2.5 mg 3 times daily. Standard carbidopa/levodopa 18.75/187.5 mg 4 times daily was substituted for controlled-release levodopa, and the bromocriptine dose was increased to 15 mg/d. Parkinsonian symptoms, including motor fluctuations and dyskinesias, improved markedly.
"However, 5 days later, the patient developed severe hypersexuality. He made sexual propositions to his granddaughter, and several times was discovered trying to maintain sexual intercourse with a female family dog. The patient was then unaware of his behavior abnormality. The reduction of the dose of carbidopa/levodopa to 12.5/125 mg 4 times daily and bromocriptine to 12.5 mg/d led to the disappearance of hypersexuality within 2 days, with only a mild impairment of the motor function
"Zoophilia (bestiality) and hypersexuality, as well as other compulsive behaviors such as pathologic gambling, should be considered as forms of impulse control disorder that can be possibly associated with the use of dopaminergic drugs in advanced PD."
Ann Pharmacother 2002 Jul-Aug;36(7-8):1178-9
Possible zoophilia associated with dopaminergic therapy in Parkinson disease.
Jimenez-Jimenez FJ, Sayed Y, Garcia-Soldevilla MA, Barcenilla B.
"A 74-year-old patient with PD was treated with controlled-release carbidopa/levodopa 25/100 mg 3 times daily and bromocriptine 2.5 mg 3 times daily. Standard carbidopa/levodopa 18.75/187.5 mg 4 times daily was substituted for controlled-release levodopa, and the bromocriptine dose was increased to 15 mg/d. Parkinsonian symptoms, including motor fluctuations and dyskinesias, improved markedly.
"However, 5 days later, the patient developed severe hypersexuality. He made sexual propositions to his granddaughter, and several times was discovered trying to maintain sexual intercourse with a female family dog. The patient was then unaware of his behavior abnormality. The reduction of the dose of carbidopa/levodopa to 12.5/125 mg 4 times daily and bromocriptine to 12.5 mg/d led to the disappearance of hypersexuality within 2 days, with only a mild impairment of the motor function
"Zoophilia (bestiality) and hypersexuality, as well as other compulsive behaviors such as pathologic gambling, should be considered as forms of impulse control disorder that can be possibly associated with the use of dopaminergic drugs in advanced PD."
