<h1>CAVERJECT</h1><p>CAVERJECT Injection contains alprostadil as the
naturally occurring form of prostaglandin E1 (PGE1) and
is designated chemically as (11α,13E,15S)-
11,15-dihydroxy-9-oxoprost-13-en-1-oic acid. The
molecular weight is 354.49.
Alprostadil is a white to off-white crystalline powder
with a melting point between 115° and 116°C. Its
solubility at 35°C is 8000 micrograms (mcg) per
100 milliliter double distilled water. CAVERJECT
Injection is available as a sterile isotonic solution in one
milliliter ampoules containing 10.2 or 20.2 mcg per mL
of alprostadil, depending on ampoule strength. The
deliverable amount of alprostadil is 10 or 20 mcg/mL
because approximately 0.2 mcg is lost due to
adsorption to the syringe during administration.
CAVERJECT Injection is also available in two milliliter
ampoules containing 40.4 mcg/2 mL (20.2 mcg/mL) of
alprostadil. The deliverable amount of alprostadil is
40 mcg/2 mL (20 mcg/mL) because approximately
0.4 mcg is lost due to adsorption to the syringe during
administration. Each mL also contains 8.2 mg sodium
chloride, 1.5 mg sodium citrate, a trace of dehydrated
alcohol, and water for injection. When necessary, the
pH of alprostadil aqueous injection was adjusted with
hydrochloric acid and/or sodium hydroxide before
filling.</p>
naturally occurring form of prostaglandin E1 (PGE1) and
is designated chemically as (11α,13E,15S)-
11,15-dihydroxy-9-oxoprost-13-en-1-oic acid. The
molecular weight is 354.49.
Alprostadil is a white to off-white crystalline powder
with a melting point between 115° and 116°C. Its
solubility at 35°C is 8000 micrograms (mcg) per
100 milliliter double distilled water. CAVERJECT
Injection is available as a sterile isotonic solution in one
milliliter ampoules containing 10.2 or 20.2 mcg per mL
of alprostadil, depending on ampoule strength. The
deliverable amount of alprostadil is 10 or 20 mcg/mL
because approximately 0.2 mcg is lost due to
adsorption to the syringe during administration.
CAVERJECT Injection is also available in two milliliter
ampoules containing 40.4 mcg/2 mL (20.2 mcg/mL) of
alprostadil. The deliverable amount of alprostadil is
40 mcg/2 mL (20 mcg/mL) because approximately
0.4 mcg is lost due to adsorption to the syringe during
administration. Each mL also contains 8.2 mg sodium
chloride, 1.5 mg sodium citrate, a trace of dehydrated
alcohol, and water for injection. When necessary, the
pH of alprostadil aqueous injection was adjusted with
hydrochloric acid and/or sodium hydroxide before
filling.</p>
