choice of liquid carrier for orals?

[jediclampet]

My friend and I were discussing how to make liquid cialis. I told him to use alcohol – but it probably won’t dissolve (from what I’d read). He asked why alcohol? Why couldn’t you just use water for example?

I told him I thought it had to do with the body’s ability to absorb the cialis from the alcohol but, honestly, I can’t give him a good explanation. I really don’t understand how we select the liquid carrier for orals in general – especially for making suspensions (i.e., when the powder does not dissolve). As far as I know we are not doing absorption studies on all these orals (nolva, clomid, Anavar (var), Winstrol (winny), dbol, drol, cialis, Viagra, Exemestane, letro, arimidiex, T3, clen, proviron etc.) to see how well the body absorbs the active ingredient in these solutions. So my question is what is the reasoning for choosing certain liquid carriers, especially for suspensions in which the powder does not dissolve? I see that some suspensions (e.g., Winstrol (winny) and var) should be put in olive oil but others (like cialis) should be put in vodka. Why?

 

[SleepingAssPirate]

It should dissolve, at least when I have used everclear & bacardi 151 ..

Now as for the reasoning behind it, its to control dosage.. again.. the powder should dissolve

you don't technically have to even do a liquid mix, you could cap it cheaply.

 

[Druss]

Liquid suspensions are 99% more accurate than capping oral powder, as cutting orals to cap is very time consuming to be done properly, while the pestel mortar method works well in theory, just the crushing of the powders, changes their desity for capping, and you cant visually look at it to actually see a homogenized mix like you can with a suspension.

Oral suspensions on the other hand dont have this problem for example

you take 5g anavar you mix this with 125ml of everclear, shake hard to get rid of lumps then mix with 375ml of glycerine, add 5ml of cherry extract and your set. Youve just made a 10mg/1ml suspension. Dont like the everclear replace with water, but if you do make sure you keep it in small bottles and use a sterile dropper or syringe to take your doses, with everclear always sterile

Everytime you take a dose you shake vigorously, the thinkness keeps the suspension homogenized for several minutes, so you dont have to worry about it settling before taking a dose.

Another alternative is making a solution instead of a suspension
Solution - powder is totally dissolved the liquid is clear
Suspension - the powder is suspended and visible in the liquid.

Easier solution take everclear example 500ml , very very cafully heat on stove or even safer in a pot of heated water (so a pot everclear in a pot hot water) Stir 5g powder around till it completely dissolves. You now have a solution of again 10mg/1ml , very strong tasting but with a very little known huge advantage, you can now take your oral sub-lingually, resulting in a much higher body absorption, by partially avoiding the first pass through the liver, what you swallow goes through first pass whats absorbed under the tongue doesnt.

Another alternative is to make an oil solution or suspension

An oil suspension, take a thick oil like virgin olive or cold pressed lin seed oil take 500ml oil to 5g powder blend until homogenized, shake vigorously before use.

Oil solution dissolve powder in BA BB
so that 5g of powder go into 2.5ml BA 10ml BB, heat and dissolve then add 490ml grapeseed oil, blend and you have an oil solution of oral powder at 10mg/1ml

Personally the everclear/glycerine suspension is easiest, while the everclear solution is probably best if you take it sub lingually, the oil based ones are good for those that avoid alcohol at all costs.

Lastly little known fact, in the USA if caught with AAS pills, each pill constitutes a charge, so that 250 pills=250 charges or counts of steroid possession, while a 500ml bottle with 5 g's of powder is 1 count.... Another wacky law en.....

You can make your concentrations as you wish

you want 100mg/ml?
5g to 50ml total liquid (be that everclear glycerine oil)

50mg/ml
5g to 100ml

25mg/ml
5g to 200ml

20mg/ml
5g to 250ml

10mg/ml
5g to 500ml

 

[dialtone]

fantastic and very helpful post druss. but, liquid orals have their issues as well. for example, you mention heating everclear to get a compound into solution. problem #1 - everclear evaporates at an accelerated rate, you add heat, its going to evaporate at an exaggerated accelerated rate therefore altering the concentration of the solution. problem #2 - even though heat brings many compounds into solution, many won't stay in solution once it is not heated (i.e. anavar). problem #3 - you could reheat the solution before each administration, but then again we run into the evaporation issue.

another huge problem with liquid orals is the horrific taste, even with flavored extracts. the staple peg+everclear combo could peel your tongue and cheeks right off. and having to administer this 2-3 times a day, 6-8 wks makes you really start to hate living.

lastly, capping is inaccurate, but to a mild degree. if aiming for a dosage of 20mg/cap, you will average 20mg/cap. meaning some will be 16mg/cap, others will be 23mg/cap. does this matter when you are taking 2-3 caps a day, averaging a daily dose of 60mg? after dealing with peg+everclear for so long, i would much rather take the slight discrepancies in concentrations of capping than have that shit corrode away everything from my lips down to my stomach lining.

great post again, reps.

 

[Cheappinz]

its the heat that will dissolve it, not the alcohol.. You could probably use water, then heat and it should dissolve given you havent exceeded a saturation point.

 

[dialtone]

its the heat that will dissolve it, not the alcohol.. You could probably use water, then heat and it should dissolve given you havent exceeded a saturation point.

i have solved many compounds in alcohol without heat. I have also crashed many compounds with heat. it depends on the compound's melting point, which varies from ~70-500 degrees. there is no single rule of thumb for liquid orals.

 

[simpllyhuge]

This is an awesome thread. Why do you suggest small bottles?

I used to use olive oil or grape seed but I never felt it was very very accurate.

 

[UserAt204]

Capping is way to easy and why even mess with liquids. The only time I made liquids is before knowing how to cap.

Like dialtone said, the in accuracy is small and you make a batch based on what you will use for your cycle so no matter what, you get the same dose.

A small food processor will make this easy and mixes your hormone and filler fairly well, leaving you with a pretty accurate dose +- 2-4mg.

 

[Pinnacle@Rep]

Some things though are very difficult to cap that require EXTREMELY small doses.
Example, anastrozole (arimidex) I make my adex at .5mg per dose whether cap or liquid. Well if you have ever tried to make a filler active ingredient mixture where the active is at .5 mg per cap....... Not really happening. So you make em in LIQUID.
Another example is T3 where the dosages are in the micrograms!!!! This is not safe to be trying to cap. Cause at 500mcg or whatever per dose if you're off 3-4 mg per cap then you could have 4-10 doses in one cap of something like T3. That can cause you some Problems!!!
Other than that I would never make liquid orals out of any other substance that needs dosages of 12.5mg per dose or higher!

 

[dialtone]

making liquid orals is extremely easy. I can make a batch of anything with some heat, water, a gram of something and a bottle where I know how much it can hold in about 3 minutes. If you use the .75ml/g weight of the powder you are using (look this up to find exacts on the powder weight) you simply subtract that amount from the water you are using. Heat it and shake well before using and you'll be fine. Remember...insignificant changes in doses don't matter to your body, just your head (except for t3 as starks mentioned).