jomamma007
New member
for those of you who have incorporated dhea into your protocols, did you notice an increase in estrogen?
It does not increase mine whatsoever, but mine is always low and I have low SHBG as well, so I am probably not the best example.
Nope. But then again, I'm pretty sure my dose of Aromatase inhibitor (AI) keeps me pretty settled in.for those of you who have incorporated dhea into your protocols, did you notice an increase in estrogen?
Yes, high doses will impact estrone mostly. An estradiol assay will not indicate the increase, and generally negligible.
what's considered high dose? Kelkels estradiol sensitive went up 8 points, that's a good amount
I was looking this up for something else and it made me think of you. Did you ever check your Total Testosterone in the method described?
Serum SHBG levels are increased in endogenous and exogenous hyperestrogenemic states, hyperthyroidism, aging, phenytoin treatment, anorexia nervosa, and prolonged stress. SHBG levels are lowered with androgen treatment, obesity, acromegaly, and hypothyroidism. In most instances, measurement of serum total testosterone will detect individuals with androgen deficiency. In conditions with abnormal SHBG levels, the total testosterone measurement (usual laboratory test requested) may be misleading. In these situations, direct measurement of free testosterone by the dialysis method, measurement of bioavailable testosterone, or calculation of the free testosterone by a formula requiring the serum testosterone and SHBG concentrations may be necessary to separate true chemical testosterone deficiency from binding protein problems. Testosterone secretion has a diurnal variation and is highest in the morning in young adult men; this rhythm is blunted or lost with aging.