wvdave, I have no idea. I am about half way through a 30 day, everyday, pin cycle with it. I guess I will know after my next blood work. I did have slightly elevated AST and ALT levels (liver tests) with my last blood work, but I had just got back from a 2 week vacation, and was drinking everyday. Doc said that could certainly cause these scores to be higher, but said that he still recommends everyone on testosterone replacement therapy (TRT) do this once a year to keep the liver functioning properly. There is some stuff out there on the internet that backs the liver benefits of this, but I had never heard of it until now, and was curious if anyone on these boards had heard of anything like this...