i don't know much about the scientific issues but, yes that seems to be a side effect, high blood sugar. I wasn't on hgh but, peptides which I guess are somewhat similar has to do with GH and I was for sure getting high blood sugar, monitored mine a lot and did extensive testing to confirm it was going up because of the peptides I was going up about 10 points after doing a shot may have even seen higher. I've completed the 3 month course and didn't really notice any benefits maybe I didn't take high enough dosages but, will probably not go back to it because it's not worth raising my bg.