Some research has shown the best time to take Growth Hormone injections is in the morning, upon awakening, but the highest release of HGH is naturally in the deepest hours of your sleep. Other research has also shown the majority of naturally produced Growth Hormone is pulsed from the Pituitary Gland at night. This has led to further studies showing that a once-a-day injection at night seem to have the most beneficial effect, while some have found injections in the morning provide the best results. A third option is distributed dosing. Small HGH injectable doses done across the day in intervals to mimic the natural pulsing of the body and so that you***8217;re not overloading your body at one time with HGH