hormone replacement therapy safe?

It's safe when monitored by a qualified physician or a well informed individual. Anything can be dangerous in the hands of an uneducated individual.
 
There is an entire section of this forum dedicated to HRT, with some very knowledgeable people receiving treatment, I suggest you read up a bit.
 
If you stay within the physiological ranges of the respective hormones, there is no reason for it to be unsafe, other than contamination or low quality source.
 
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