Var wont necessarily " kick in" as its not a steroid which drastically changes your physique overnight. Dont be confused you would start to notice your strength increase and muscles hardening after about 2 weeks but dont expect to step on the scale and see a drastic change. Var is a bit more gradual especially at only 50mgs ed. Advice: var should jack up your strength, use it and lift heavier than u ever have before. This heavy ass lifting will cause the corresponding muscle growth you are looking for. However if you are chubby and/or do not have a really good diet, forget about it, you wont notice anything of note