Here's something that I wrote previously about Dostinex/Cabergoline:
Use/Dosing
Due to the extremely long active life of the drug, approximately seven days, users only have to administer their doses once or twice per week to see good results. In terms of the dosing that healthy individuals would need to use to suppress prolactin levels raised by their use of anabolic steroids, anecdotally many users report seeing their best results with dosing in the range of one half of a milligram to one and a half milligrams of cabergoline per week. This dose range should be sufficient for the majority of users but larger doses can be used as there appears to be little worry for users in terms of toxicity except at extremely high doses that would be impractical to administer unintentionally (11, 12).
Cabergoline reaches its peak plasma concentration within two to three hours if administered orally. The drug is metabolised by the liver with a relatively large amount of the drug experiencing a first pass effect (13). Users are able to take the drug with or without food; there is no impact on the absorption rate or action of the compound in either case. In healthy subjects it has been determined that the elimination half-life of cabergoline is between sixty-three and one hundred and nine hours (13). There is no reliable data on the detection time of the compound.
In terms of the duration of time that users can administer cabergoline, there is very little research that has been completed on the subject. As will be discussed in the Risks/Side Effects portion of this profile below there are some indications that there may be risk factors involved in the long term use of the drug but no definitive conclusions can be made. However, at least in terms of the short term finding, it appears that cabergoline is a relatively safe drug for use by healthy adults for long periods of time.
