Hypothyroidism is associated with increased myostatin expression in rats.

Lmfao



Yeah, it looks like optimizing thyroid might have a positive effect on anabolism. I've seen accounts of people adding small amounts of T3 to increase protein synthesis. Looks like those guys were on to something. I never thought hypothyroidism could have a negative effect on protein synthesis. I actually read another study which showed the endocrine state of bears during hibernation. They go into a hypothyroid, hypergonadal state in order to bulk up for the winter. Pretty wild stuff
 
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