Is Human Chorionic Gonadotropin (HCG) Sensitization Real?

[ebracer05]

Is HCG Sensitization Real?

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[H 3 L L S M A N]

You do not want to over do HCG. Just do the math and make sure what you are measuring is 250iu and twice a week.

 

[bcopp]

Just do 250mg 2-3 times per week on cycle and your balls should stay normal. Don't worry about desensitizing your leydig cells with that dosing.

 

[Moppy1]

I'm wondering if HCG sensitization is a real phenomenon and if so, what sort of dosage does it take to achieve it? I see some bros on here recommending running 250IU-1,000IU per week on cycle and sometimes also an HCG blast post cycle therapy (pct). I don't want to permanently damage my testicles so can HCG cause damage to the Leydig or Sertoli cells?

I'm on week 8 of a 500mg TE 600mg EQ cycle and my balls are about half the size they were. I f*cked up my measurements and thought I was pinning 250IU weekly HCG but it turns out I was only pinning 125IU! When I realized this a few days ago, I pinned an addition 250IU and want to know what the best protocol would be to help restore my testicle size, at least somewhat, while I finish the cycle. I was thinking of 250IU 3x per week and then blasting 10 days after the last injection (I'm stopping EQ a week before TE so I don't have to worry about the 3 week clearance of EQ). My GF has noticed my balls are definitely smaller and it's been a tough topic to divert, especially with my ridiculous sex drive!

Thanks guy!

There are hundreds of good medical studies on HCG treatment for hypogonadotropic hypogonadism (small balls) in men across the world. Meta-analysis suggests a very profound effect, and as much as 3-fold increase in testicular size in responders. The typical dosage is 500 IU three times a week, for as long as 6 months so men can father a child. This seems to be the medically proven best treatment dosage over the past few years, and all the aging clinics are adopting it. In fact, most of the aging clinics that prescribe testosterone replacement therapy (TRT) also recommend HCG use throughout your cycle (500IU, 3x a week). Some medical studies also go as high as 1000 IU, 3x a week, and show a better response. There are NO data to suggest a "burn-out" effect of HCG on the testis, but it could negatively impact the pituitary and your ability to make natural FSH and LH in the future....just has not been looked at in medical studies yet.

 

[UserAt204]

You are fine, you don't have to use hcg on an 8 week cycle but IMO its always good to use.

At the doses you are using, 250 2-3 times a week you won't have any issues. Taking NAC 600mg a day will help prevent desensitization.

But hcg is used at 5000iu all the time in a uro's office and for fertility can be used at some high doses for long periods but there is less risk because they are trying to restore what's already lost.

You may or may not have some atrophy but it shouldn't happen to fast and you don't need more than 250iu at one time while on. If 2 x a week isn't working do 3, but it's also not an instant fix so relax and quit starring at your balls all day.