Lowering Prolactin - What works... and what doesnt

[jedi_master]

I've been around the boards for quite some time, but this is the first time that i've felt the need to post and that I can contribute and offer up some good data that may help someone out.

I have been cycling for 4 years now and have zero problems with estrogen, I have run high test cycles with other compounds for long periods of time and not ever once had itchy nipples, but boy am I sensitive to prolactin!!!! I looooove progestin steroids, Tren is my bread and butter...but it makes me lactate like crazy.

I am probably one of the few people who has tried every solution for lowering prolactin and I would like to share with you my findings, as I feel there is ALOT of misinformation on the subject... especially regarding prami.

Here are a list of the methods I have tried, I will go over each in more detail.

- Pramipexole
- Bromocriptine
- T3 (cut off progesterone production at the thyroid)
- High dose B6
- Winstrol (Supposed anti progestin activity)
- Control Estrogen = Control Prolactin
- St Johns Wart
- Cabergoline


Pramipexole

This has got to be the worst substance I have EVER put in my body ever. period. In the forums there is alot of anecdotal evidence of what prami does and how wonderful a drug it is and people preaching to use it over all else... but straight up this couldnt be further from the truth.

IF you can handle the sides of prami first off you are a masochist but second probably still wasting your time. I ran it for 3 weeks and managed to get up to 1mg a day and it did jack s**t for me in terms of lowering prolactin.

Of every drug I've ever put in my body, prami has had the worst side effects bar none. Tren's supposedly horrible sides feel like a day at disney land compared to the pain and misery prami will bring into your life. Unfortunately, prami is the most readily available drug for lowering prolactin.

Don't waste your time on Prami. If you've bought some, chuck it in the garbage.

Prami Sides:
- Severe nausea
- Abdominal cramping
- Vomiting
- Living in a weird "Dream State" (best way to describe it)
- Feeling like a zombie, always in a haze
- Zero appetite
- Piss the color of Coke (this can't be good)
- Oddly enough strength went up but I didnt have enough energy to do more than a couple sets

Verdict - Waste of time



Bromocriptine

After giving prami a shot with no luck, I went to the walk in and told the doc Im just coming off a big tren cycle and I got milky nips. I squeezed my tits for him and he gave me a script for some bromo. Easy peasy.

I took bromo for 3 weeks and it reduced the majority of the soreness and lactation althogh there was still some. I believe I was taking 2.5mg twice daily?

So bromo works, It didnt work perfectly but I had bloods done and it got me down to slightly high range of normal within 2 weeks at a moderate dosage.

Bromo Sides:
- Extremely low blood pressure (im talking stand up and pass out)
- Head Aches
- Slight Nausea

Verdict - Good to go



T3

I have read in a few places that since progesterone is regulated by the thyroid, you can lower prolactin by controlling progesterone with exogenous t3.

All t3 did was get me ripped as hell haha. God I love T3 but it wont do a damn thing for prolactin.

Verdict - Bunk for this purpose



High dose B6

This was interesting, Supposedly high dose B6 lowers prolactin as effectively as Bromo. I picked up a couple vials at the drug store and ran 300mg twice daily for 2 weeks.

My nipples felt a little less sensitive after 2.5 weeks but still were lactating, so this did not work very well for me.
A few people have said high dose B6 has helped them (StoneCold is one I believe) but I may just be too sensitive to prolactin and didnt find it strong enough. For the price and availability though its worth a shot!

Verdict - Helps Slightly, worth a shot



Winstrol

People have said that Winstrol has anti progestenic properties but by adding winstrol to my cycle I perceived no change in prolactin side effects.

Verdict - Bunk for this purpose



Control Estrogen = Control Prolactin

This is a very common misconception. A few people have had very strong opinions that by controlling estrogen you will not suffer ANY progestogenic side effects. This is simply not true!! Although this may help, it will NOT fix the problem, Presence of Estrogen will aggravate prolactin but controlling estrogen will not eliminate prolactin.

If you are sensitive to prolactin you must control prolactin! (you should always control estrogen anyways though)

Verdict - Misconception



St John's Wart

This was just a waste of time. Dont bother!

Verdict - Bunk



Cabergoline

(Best for last)

Okay here we go. This is the HOLY GRAIL of ancilliaries for 19 nor steroids! Cabergoline is the ONLY thing that truly helped my prolactin problem, and it did it fast!

After 1 week (2 Doses of 500mcg) My prolactin is GONE. My nipples are no longer remotely sensitive, I have ZERO lactation, my nipples sit flat against my chest which is wonderful and I have the sex drive of a 12 year old boy. Im not kidding I get random woodys all the time and i've just been slamming my girl like its nobody's business, after months of a diminished sex drive.

Caber is STRONG and EFFECTIVE and has zero sides except for incredible sex drive and stronger orgasms.

This is what you need if you love to run Deca or Tren. Its not as easy to get a hold of and its its much more expensive but god damn its worth it!


Verdict - This is what you NEED!



So there you have it Gents. A comprehensive review of every popular solution for controlling prolactin. I know its long but I hope It may eventually be useful for one of you. I just wanted to give back some information to the community. If you have any questions etc. you can shoot me a PM.



Happy cycling
- Jedi

 

[halfwit]

Great writeup, thanks for posting this!

 

[SolomonGrundy]

thank you, good info anyone can understand ! +++

is the caber dose .5mg twice a week

 

[Chi23]

Great info here thank you.

 

[jedi_master]

Yea I took .5mg monday and friday first thing in the AM. Works like a charm!

thank you, good info anyone can understand ! +++

is the caber dose .5mg twice a week

 

[Dr.Phoenix]

Great Post , Well Researched
Thanks for your efforts

 

[thades]

^^^yup, i dose my caber at .5mg twice a week, only exception being if i'm runnning really high dose deca

 

[Dr.Phoenix]

Some Greens for you

 

[MeatHead96]

Good post man but your findings are strictly based on the way you react to these methods. I do just fine with prami and don't experience sides like you do. I have tried most of these things too and I like prami the most. Just because one thing doesn't work for you or you have a hard time with sides doesn't mean its the same for others. I am in the same boat as you with having prolactin issues. Estro never caused me problems but deca fucks me up. Caber and prami I feel are best. Caber is awesome and has no sides for me either. Prami I can't take at night because it gives me insomnia and I had some sides from it initially but my body adjusted. Now I like the way it makes me feel and the effects of it. I use it even when not using 19nors at .25mg twice a day.

 

[blacktoppete]

Thanks for he great post. This what we need

 

[horusculture]

Prami is no good ?

 

[jedi_master]

I used RUI prami for 3 weeks and after getting bloods done my PRL was 15 ng/mL if i remember correctly (mens range is 3-13), 3 more weeks of 5mg bromo had me down to 12.5 ng/mL (high range of normal). It could be that I did not run prami long enough or at a high enough dosage to effectively lower it but I was up to 1mg ED and I just couldnt handle the sides.

Some people as MeatHead69 stated may have a different experience, if you can power through the effects and run it at higher dosages for a longer period of time im sure it will help as it is a dopamine agonist and dopamine inhibits prolactin.

From my personal research I have found that prami just isnt strong enough to keep prolactin in check and the sides for me are just too much. (Im not a pussy either, sides usually dont bother me much)

If you can get your hands on caber it is THE drug to run while cycling with 19 nor steroids. It is the most effective at controlling prolactin and it does it fast and without sides. The only reason caber exists is to lower prolactin. Bromo would be my second choice as it works but isn't as strong as caber.

 

[fitnessgeek]

Great post-Thanks for the research!

 

[horusculture]

Im running .5 prami e3d from rui maybe I should up to ed

 

[builtbeast]

Im running .5 prami e3d from rui maybe I should up to ed

Prami has an 8hr half life so you need to run it ED or it's worthless.



To the OP, is the caber research grade or an actual pharma product? I've found RC to generally suck in comparison to pharma, even if it's from asian countries.

Also, I liked prami as well as caber. I've tried the b6 and Aromatase inhibitor (AI) only and neither of those worked for me either. Prami is great if you can tolerate it but if not then caber it is.

 

[horusculture]

Prami has an 8hr half life so you need to run it ED or it's worthless.



To the OP, is the caber research grade or an actual pharma product? I've found RC to generally suck in comparison to pharma, even if it's from asian countries.

Also, I liked prami as well as caber. I've tried the b6 and Aromatase inhibitor (AI) only and neither of those worked for me either. Prami is great if you can tolerate it but if not then caber it is.

Can anyone pm me a domestic source for caber

 

[Bret5089]

Awesome post man! Thanks for the info!

 

[THE-DET-OAK]

Good post, but I think your missing that PRL and PGR problems are 2 separate issues.

Also just so you guys know, I don't even consider tren a progestin, it has barely any affinity to the PGR receptor, if at all. So you will not need anything with it.

Winstrol

People have said that Winstrol has anti progestenic properties but by adding winstrol to my cycle I perceived no change in prolactin side effects.

Verdict - Bunk for this purpose





Happy cycling
- Jedi

 

[jedi_master]

Hey Thanks for taking the time to read my post.

Although PRL and PGR are 2 different problems there is a DIRECT link between the two.

progesterone [pro-jes´te-ron]
a steroid sex hormone that is the principal progestational agent; it plays a major part in the menstrual cycle. During the maturation of the secondary oocyte (ovum), estrogen, the principal female sex hormone, is produced at a high rate. At ovulation estrogen production is sharply reduced, and the ovary then creates within itself a special endocrine structure called the corpus luteum whose sole function is to produce progesterone. Unless fertilization takes place, the corpus luteum disappears when it has performed its function. The progesterone it has produced is promptly carried by the blood to the uterus, as was the estrogen previously. Both hormones now work to prepare the uterus for possible conception.

In pregnancy progesterone acts in a way that protects the embryo and fosters growth of the placenta. By decreasing the frequency of uterine contractions it helps to prevent expulsion of the implanted zygote. It also promotes secretory changes in the mucosa of the fallopian tubes, thereby helping to provide nutrition for the fertilized ovum as it travels through the tube on its way to the uterus.

Another function of progesterone is promotion of the development of the mammary glands in preparation for lactation. prolactin, from the anterior lobe of the pituitary gland, stimulates production of milk, and progesterone prepares the glands for milk secretion.

Miller-Keane Encyclopedia and Dictionary of Medicine, Nursing, and Allied Health, Seventh Edition. © 2003 by Saunders, an imprint of Elsevier, Inc. All rights reserved.

And whether or not Tren has much of an affinity to the PGR receptors Tren raises prolactin, PERIOD. Some people have no problem running tren and will never lactate. If you are sensitive to prolactin and progesterone then you must run caber if you wish to control your serum prolactin levels and avoid fina-dick as well as puffy lactating nipples.

 

[jedi_master]

I got caber capsules from a reputable UGL, Ive read that caber isn't stable in a liquid solution and will deteriorate in under a month. So I would steer clear of the research chem caber and try to look for tabs or capsules!

To the OP, is the caber research grade or an actual pharma product? I've found RC to generally suck in comparison to pharma, even if it's from asian countries.