Metformin diabetes drug may also extended lifespan.

anzel

New member
Around the forums you may see talk of metformin (Glucophage) as a form of GDA (glucose disposal agent) and a bodybuilders way to manipulate insulin instead of using actual insulin.
Well now a committed group of scientists is seeking to validate metformin as the first ever anit-aging medication.
In this day of staggering drug prices,metformin is available as a low-cost generic.
The FDA has approved the first anti-aging study to be done with this drug....

Anti-Aging Human Study on Metformin Wins FDA Approval
March 2016

By Judy Stevens

News Reports around World Describe Multiple Benefits
The media has caught up to the potential health benefits of metformin, something our long-term supporters discovered long ago.

What caught the media's attention was the FDAs approval of the first human study to see if metformin can protect against the multiple diseases of aging.

Prominent headlines around the world proclaimed:

New Anti-Aging Drug Could Extend Human Life Span to 120 Years

Metformin of course is not a new drug. It was approved in England in 1957 and made available to type II diabetics around the world shortly thereafter. It took the FDA a staggering 37 years to approve it in the United States.

Here are some accurate quotes from worldwide news sources:

News Reports around World Describe Multiple Benefits
Although it might seem like science fiction, researchers have already proven that the diabetes drug metformin extends the life of animals, and the Food and Drug Administration in the US has now given the go-ahead for a trial to see if the same effects can be replicated in humans.

I have been doing research into aging for 25 years and the idea that we would be talking about a clinical trial in humans for an anti-aging drug would have been thought inconceivable20 years ago aging was a biological mystery. Now we are starting to understand what is going on.

Scientists think the best candidate for an anti-aging drug is metformin, the worlds most widely used diabetes drug, which costs just 10p [15 cents] a day. Metformin increases the number of oxygen molecules released into a cell, which appears to boost robustness and longevity.

If we can slow aging in humans, even by just a little bit, it would be monumental. People could be older, and feel young.

This would be the most important medical intervention in the modern era, an ability to slow aging.

Even the venerable Dr. Robert Temple, deputy director at the FDA, chimed in by stating:

Their hope is that a wide variety of age-related problems, loss of muscle tone, dizziness, falls, dementia, loss of eyesight, all of those things [sic]. That would be something never done before. If you really are doing something to alter aging, the population of interest is everybody. It surely would be revolutionary if they can bring it off.

Dr. Simon Melov of the Buck Institute for Research on Aging added:

Youre talking about developing a therapy for a biological phenomenon which is universal and gives rise to all of these diseases. And if you;ve got a therapy for this thing, these diseases just go away.

Life Extension® Has Championed Metformin for 20 Years
Life Extension® magazine listed metformin as one of many important offshore medications back in 1995. And now, 20 years later, even the FDA concurs that metformin has potential to delay the onset of degenerative diseases.

But contrary to news headlines, metformin will not enable humans to live to 120 years of age all by itself. What it may do is allow humans to age better today thereby staving off degenerative diseases long enough for age-reversal breakthroughs to become clinically available.

Metformins Primary Anti-Aging Mechanism
Metformin enhances the activity of an enzyme found within our cells called adenosine monophosphate-activated protein kinase or AMPK for short. AMPK activation helps mimic the beneficial effects of calorie restriction, the best documented method of slowing and reversing biomarkers of human aging.

We at Life Extension® have long endorsed AMPK activation as a method of slowing biological aging. We advocate that our supporters utilize some proven method to increase their cellular AMPK activity, which could add substantial healthy years to the average life span.

How to Boost Your AMPK Today!
How to Boost Your AMPK Today!
We do not want you to age prematurely, waiting years for the results of the new FDA-approved human study. Thats why we recommend you initiate steps now to boost healthy AMPK activity today.

One of the benefits of practicing consistent calorie restriction is a substantial increase in AMPK activity as cells go into a semi-starvation mode and increase their survival efficiency.

People under age 60 who regularly/vigorously exercise boost their AMPK levels. This may be the mechanism by which exercise markedly lowers cancer risk. As people age past 60, exercise may not adequately boost AMPK enzyme activity.

If you;re presently taking 1,000 to 2,550 mg of metformin daily, you don't have to do anything, simply enjoy this drug's anti-aging benefits. But if you cannot acquire a prescription for metformin, or cannot tolerate it due to digestive issues, there are nutrient formulas that have been shown to significantly boost AMPK activity.

Anti-Aging Human Study on Metformin Wins FDA Approval - Life Extension

Enjoy your day!
Anzel
Euro-Pharmacies.net
 
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No research here by me, BUT I was told by one of my doctors that my use of Metformin for my Type 2 diabetes can have a bloating effect on my stomach. So one of the things I have done to help my Bloat as discussed on my thread "distended stomach on cycle" thread is to stop my metformin.
 
Ahh...so that stinks...
And I talked with another metformin user and they mentioned feeling depressed on it...

Well Life Extension keeps going on and on about it...it's not like they can actually sell it cause it's a prescription drug and they sell supps. So their articles are very pro metformin with no mention of sides.

Thanks Mike!

Anzel
Euro-Pharmacies.net
 
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