Original substance effective only or also metabolites ?

[Gtrack]

Are the substances we take the only ones that are effective or also their metabolites ?
Test metabolizes to estrogens,DHT etc but also to many others that could or could not be effective too.

 

[BigRonWannabee]

Well quite simply the metabolites are effective in their own right. Estrogen is highly anabolic for example. A slightly higher estrogen environment is actually favorable for strength and protein synthesis.