Currently taking Danazol to keep it dialed in.
Do you guys ever worry about the long term effect of taking drugs that were never approved for this use (off label)...like danazol, AI's, stan, etc?
I figure we are all lab rats when it comes to lifetime test, but just wonder about the other "stuff."
As regards the OP question, with a test of 1000, the SHBG will be physiologically lowered as high levels of test normally suppress SHBG production in the liver. Wouldn't be surprised to see it fall significantly from your initial value.
do you guys ever worry about the long term effect of taking drugs that were never approved for this use (off label)...like danazol, ai's, stan, etc?
I figure we are all lab rats when it comes to lifetime test, but just wonder about the other "stuff."
as regards the op question, with a test of 1000, the shbg will be physiologically lowered as high levels of test normally suppress shbg production in the liver. Wouldn't be surprised to see it fall significantly from your initial value.
Do you guys ever worry about the long term effect of taking drugs that were never approved for this use (off label)...like danazol, AI's, stan, etc?
I don't know where you read SHBG is going to be suppressed from high testosterone.
Don't really know where to begin, except just to tell you to do a little more research - but basically in a nutshell, test has a regulatory effect on the liver, higher levels of test suppress SHBG synthesis in the liver, hence high test, low SHBG. Most guys (you may be an exception) will find their SHBG fall to half of its pre-TRT value if their test is on the high side.
hey bro... My days of getting into pissing contests with guys like you are long since gone. It's quite obvious that you are one of the few left out there that have an agenda against hrt/trt. It's made very clear by the fact that none of your posts are ever helpful or even humorous, yet rather you sit back and lurk and try to find ways of being combative. I really think that we should all let you have your moment in the sun..... Start up your very own "why i hate hrt/trt" thread and we all promise to read it so it will show you how many views you got. Ok? Sounds great!
Ah, Chipster, how wrong you truly are.
Sorry if I come across as a “lurker” and just “chip” away [no pun intended] at much of the well-meaning crap often posted here. And you know, you’re right about one thing, most of guys who seem to post here, as contrasted to a number of the other boards, would be just as happy not worrying about potential side effects of the off-label scheduled drugs they are using, nor any consequences of using them for decade after decade.
Oh yes, ‘bout me. Have only been on testosterone replacement therapy (TRT) a short time, but not before having fully explored the gels and alternate therapies (AI, Human Chorionic Gonadotropin (HCG), etc -monotherapy), only to realize that at my age, test injections were my only alternative.
I’m a great advocate of TRT!!
However, it concerns me that so many younger guys (a relative term for me, but anyone in their mid-30s or less) don’t give proper consideration to alternate therapies that might actually succeed for them. It also disappointing that so many of the bro’s who post here are so willing to swallow (both literally and figuratively) anything in their endless chase to manipulate substances (SHBG, E2) that are best controlled through less invasive means (if possible).
I think you and your Maximus company provide an invaluable service to the testosterone replacement therapy (TRT) community. I guess the best way to have shown my appreciation and respect for what you do is by counting myself as a happy client of yours! Dealing with you personally has been alot more enjoyable than giving you shit on a internet forum!

Ah, Chipster, how wrong you truly are.
Sorry if I come across as a “lurker” and just “chip” away [no pun intended] at much of the well-meaning crap often posted here. And you know, you’re right about one thing, most of guys who seem to post here, as contrasted to a number of the other boards, would be just as happy not worrying about potential side effects of the off-label scheduled drugs they are using, nor any consequences of using them for decade after decade.
Oh yes, ‘bout me. Have only been on testosterone replacement therapy (TRT) a short time, but not before having fully explored the gels and alternate therapies (AI, Human Chorionic Gonadotropin (HCG), etc -monotherapy), only to realize that at my age, test injections were my only alternative.
I’m a great advocate of TRT!!
However, it concerns me that so many younger guys (a relative term for me, but anyone in their mid-30s or less) don’t give proper consideration to alternate therapies that might actually succeed for them. It also disappointing that so many of the bro’s who post here are so willing to swallow (both literally and figuratively) anything in their endless chase to manipulate substances (SHBG, E2) that are best controlled through less invasive means (if possible).
I think you and your Maximus company provide an invaluable service to the testosterone replacement therapy (TRT) community. I guess the best way to have shown my appreciation and respect for what you do is by counting myself as a happy client of yours! Dealing with you personally has been alot more enjoyable than giving you shit on a internet forum!
OUCH. I THINK YOU MAY HAVE FRIED MY ASS ON THAT ONE.
THESE DAMN AVATARS AND SCREEN NAMES WILL GET YOU EVERY TIME. I'M NOT REALLY SURE WHAT TO SAY, ASSUMING THAT YOU ARE A SATISFIED CLIENT OF "TEAM MAXIMUS", OTHER THAN THE FACT THAT IT SEEMS I HAVE BEEN HUMBLED A BIT. I AM DEFINITELY NOT TO BIG OF A MAN TO EAT MY HUMBLE PIE WHEN/IF I DESERVE IT.
OVER TIME, WE HAVE DEALT WITH A FEW RECURRING "LURKERS" THAT JUST TRY TO CREATE SHIT FOR ALL OF US. I'M SORRY IF I DID, IN FACT, MIS LABEL YOU.

Would you mind sharing your protocol with us?
No secrets.
65 mg test every 84 hours +250IU Human Chorionic Gonadotropin (HCG) and if absolutely necessary, a tiny amount of Adex.
Rule 1 and 2: I don't "chase" SHBG or worry too much about E2. SHBG will go where it wants, E2 needs to be "managed" only at higher levels (can't give exact numbers, but something over 30-50 or a bit more). E2 is your "friend" and is critically important for bone function.
Rule 3: diet is everything.
Rule 4: if you don't feel good, consider the other two endocrine systems (adrenal, thyroid) before going off on tangents.