Just to add a little extra, received a PM... This applys here so thought I would post it up
hiram1st said:
Do you have concern about desensitizing the testes? There are studies that blasting Hcg does that.
Everyone here preaches no hcg for pct because it's a hpta suppressive and to use clomid and Nolva together.
I know you've been around a while. Would like to here your take on this.
Thanks
Yes absolutely, hCG can cause the leydig sells to desensitise if the dose is high enough and for prolonged periods. hCG used correctly, typically for a TRT protocol ~200mg Test/1mg Adex/500iu hCG all split up throughout the week is perfectly fine and replicates something close to the equivalent of natural leydig cell stimulation from natural levels of LH.
750iu of hCG EOD for 4 weeks is enough to wake the balls up so to speak, however I will be running the 250iu along with my TRT protocol as if it was how I would be running it if I was to use hCG. It is also a trial for me to see how I respond to having hCG in the mix with my Test and Adex as a lot of guys report it brings back the sense of well-being that is lost in some cases. It must have something to do with downstream hormones from Pregnelone that is shut down from exogenous Test administration/LH shut down.
If I feel better with hCG I may just continue on, however if I come off, my testicles will have been running for 3 months so I can come off the Test and be running on my natural systems.
Which brings in the question, yes hCG is suppressive to to HPTA in that in will stop LH/FSH like AAS will do and this is why you don't need to run a SERM with hCG (in that it also will stimulate LH along with the exogenous hCG causing possibly too much stimulation of the leydig cells), however the systems that LH/FSH stimulate will already be running so it is just a matter of the hCG clearing out and then LH signal comes on fairly quickly and takes over what hCG was doing with (and this is the idea) no lag in recovery waiting for your testicles to come back on and your body pumping out estrogen to compensate whilst at the same time that estrogen is keeping you shut down via negative feedback.
Dropping the hCG and then switching to Toremifene will stimulate LH levels naturally somewhat as well, whilst also blocking breast tissue preventing and/or removing any existing gyno and take care of any extra e2 that is associated with a recovering HPTA... I may even get bloods done mid-way through Toremifene to see where everything is at and use an AI to keep e2 controlled as well but I don't think it will be necessary.