Want to add HCG to Testosterone, need some advice

kilo7

New member
Hello!

I started TRT in September. I get 250mg T-enantate every 2-3 weeks. That's the best I can get cause my endo is conservative
and will not try out anything "out of the book". But that's not the problem here.

Actually since starting the injections I noticed some changes. I get more morning woods. But other than that I cannot feel that I "feel" having more T.
I do NOT get any mood swings which surprises me. I do not feel the highs. I'm not sure if this is normal. I also had my T levels checked after 7 days where they are supposed to peak and my level was at the top of the normal range but not above it. But from what I read in books the level should be above the normal range when it peaks. My E2 is around 25 which is okay, it's similar to my E2 before going on TRT so it doesn't seem to go up.

BUT the big problem is my balls. They have shrunk dramatically and I feel like I cannot just sit there and watch. They are very small and soft and the scrotum is tight nearly all the time. I asked my endo about adding hcg and he said no.

I'm considering adding hcg on my own but I have a few uncertainties. I hope that the people here can help me.

1) How safe is hcg? Does it have any major side effects or drug interactions? (I'm also on Cymbalta (antidepressant))

2) Is using hcg dangerous for the testicles? I read that it can desensitize the Leydig cells. Is this also the case when using low doses of HCG?

3) How likely is it that HCG would raise my E2? If I also needed to add an AI then this would be a problem because of the costs and also because I want to avoid taking too many drugs because of possible drug-drug interactions.

4) I already looked online and there are 5000 IU vials available. Do you know how long they keep fresh in the fridge? If I wanted to inject 250 IU every other day then a vial needed to stay fresh approximatively 6 weeks.

5) Would I have to keep injecting HCG constantly forever? Or could I also cycle it in order to make the tests blow up a bit and then wait until they shrivel up again and then start a new cycle?
 
1. It's safe. It just mimics LH in your body.

2. I wouldn't call it dangerous to your testicles, but it will shut down your body's own production of LH. As far as the Leydig cells, I heard that can occur at high doses (over 1,000 IUs several times a week).

3. Yes, HCG can raise your e2, but the only way to know for sure is blood work. .25mg of Adex 2x a week shouldn't be that expensive, and it should be fine to take with other meds. You could also try the natural supplement DIM, although it wouldn't be anywhere near as effective as Adex.

4. They say 30 days, but you should be fine up to 60 days. I heard pharm HCG, like the Pregnyl brand, may hold it's potency longer than something from a compounding pharmacy.

5. As long as you're on T, I would stay on HCG, at least 2x a week. Some do 250 IUs 2x a week, but I read somewhere that 500 IUs 2x a week will preserve fertility. Don't go off HCG and let your balls shrivel, as it may cause irreversible damage if they're shut down long enough. The key is to keep dosing HCG regularly to prevent that from happening.
 
2. I wouldn't call it dangerous to your testicles, but it will shut down your body's own production of LH. As far as the Leydig cells, I heard that can occur at high doses (over 1,000 IUs several times a week).

More like over 10,000 IU dosages :)
 
Hi, thanks for the answers.

Fertility is no concern to me. I am not going to have kids.
What worries me is simply that the testicles become too small. I also wonder does the shrinking ever stop?
My scrotum is tight all the time and I can hardly even feel the testicles. This is really annoying.

Do you know what could happen if the hcg is kept in the fridge for too long and not fresh anymore? Is this a hygienic issue with bacteria and infections?

And I also read that there are no long term safety studies with hcg use. What if hcg use could lead to testicle cancer or something like that?

Are there also alternatives to hcg, which could also raise LH in the body? Or is hcg the best choice? I want something with as little side effects as possible.
 
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