100mg/5 days vs. 200mg/10 days....

[LongBeach_Patriot]

I've been on TRT for about 5 months now. Originally was 200mg of Cyp every 14 days, then I was able to talk my Endocrinologist r into lowering it to every 10 days because my peak and trough Test levels were very far apart (about 1150 peak and 250 trough on the 14 day cycle, and with the 10 day cycle the trough was at 550). The doc lets me go to my GP to get the injection so I dont have to pay a big copay every 10 days. I've been self injecting because I dont wanna pay a GP copay lol. A buddy of mine who cycles AAS and is very knowledgeable about gear, training, ect taught me.

So what I'm considering now is to do 100mg every 5 days to keep things even more level. There no difference in overall dose and I was advised from my friend that theres no negatives and only positive benefits from doing it this way. I know I'll have to use 4 injection sites though so the only negative I can see is more injections/scar tissue.

I would appreciate some advice as to whether its worth it to change to a 5 day cycle or keep it 10.

Thanks,

 

[Megatron28]

Your friend is right. In fact, a lot of us pin every 3.5 days. It helps keep levels more even and reduces aromatization.

 

[LongBeach_Patriot]

Your friend is right. In fact, a lot of us pin every 3.5 days. It helps keep levels more even and reduces aromatization.

Thanks man. My E2 never got too high on either frequency so I never has issues with that as close to equilibrium is what I want. The doctor actually lowered my dose from 200 to 175 to so its actually been 175mg every 10 but I think its pretty dumb personally. My Test wasnt thattt much higher when I was on the 200. I think peak was 14-1500. Such a PITA measuring out .45ml in a syringe and itll never be exact. Maybe just do the .5 and if I run out before the script is due to be written for me I'll pick up another bottle not from the doc.

In the long run though its ok to pin every 5 days????? That's really all Im concerned about, cause I'm a lifer for sure. My natural production is shot.

 

[Megatron28]

Every 5 days is fine if you don't have big swings or estradiol problems. Lots of guys have great results pinning every 5 days. You will need more injection spots though. Quads, delts and glutes are all great spots. Try to use at least two of those.

 

[LongBeach_Patriot]

Every 5 days is fine if you don't have big swings or estradiol problems. Lots of guys have great results pinning every 5 days. You will need more injection spots though. Quads, delts and glutes are all great spots. Try to use at least two of those.

Great, I appreciate the prompt and informative response.

Final questions: When should I start the 5 day frequency? This Friday would be day 10/my next scheduled injection. And then also should I get bloodwork after doing the 5 days for a little while to see how my body is reacting? If so, when should I get the bloodwork done and should it be on day 1 or 2 or 4 or 5? or 3? lol.

Thanks again amigo,

 

[Megatron28]

Start the new pinning schedule on your next pin day.

Get blood work in about 6 weeks after changing frequencies. I personally like checking peak and trough levels when you make a change. So about 1-2 days after pinning and right before you pin.

 

[Mprtz]

There is one negative to going 5 days, depending on your goals and your point of view:

Because your levels will be more even, your trough will be higher. Since that is typically the only thing your doctor sees, he is more likely to reduce / less likely to increase your dose.

 

[LongBeach_Patriot]

There is one negative to going 5 days, depending on your goals and your point of view:

Because your levels will be more even, your trough will be higher. Since that is typically the only thing your doctor sees, he is more likely to reduce / less likely to increase your dose.

Im not totally sure what your saying but I think your saying that its going to increase my levels overall but im actually keeping the dose the same im just injecting more frequently to prevent a lower trough but the peak shouldn't necessarily increase much. Maybe I'm wrong. Either way, I get blood work taken at my gp and they let me bring it/send it to my endocrinologist so what momma dont know wont hurt her.

 

[Alpin]

Your friend is right. In fact, a lot of us pin every 3.5 days. It helps keep levels more even and reduces aromatization.

I've always wondered what the aromatization is like on a 60-80 mg individual T shot...
I know I've seen my Estradiol rise to 340 pmol/l(92 pg/ml) 48 hours after 160 mg Shot....
Although my TRT doc said it was errored by the lab, because they are notorious for messing up Estradiol Tests.
He said that my Estradiol was closer to 200 pmol/l (54/pg/ml) on that test.
He won't give me another lab req. to run to verify....jerk!

 

[Mprtz]

Im not totally sure what your saying but I think your saying that its going to increase my levels overall but im actually keeping the dose the same im just injecting more frequently to prevent a lower trough but the peak shouldn't necessarily increase much. Maybe I'm wrong. Either way, I get blood work taken at my gp and they let me bring it/send it to my endocrinologist so what momma dont know wont hurt her.

It's the same amount of medication, but injecting once in a 10 day period, you might peak at 1500 and fall to 650.
Injecting half that amount every five days you might peak at 1250 and fall to 900.

Yes, the latter is better because it is more steady, but if your doctor no way wants you over 800 (all numbers hypothetical), then he will reduce your dose in the second case but not the first.

 

[Daniel_IMT_Staff]

Agree with mprtz and just for further clarification LongBeach_Patriot: Trough is the reading right before you are about to take your next shot. It's a type of reading, you can get a peak plasma concentration which is just a the highest your T level will be.

 

[methos0123]

Im not totally sure what your saying but I think your saying that its going to increase my levels overall but im actually keeping the dose the same im just injecting more frequently to prevent a lower trough but the peak shouldn't necessarily increase much. Maybe I'm wrong. Either way, I get blood work taken at my gp and they let me bring it/send it to my endocrinologist so what momma dont know wont hurt her.

This is false. Your peak WILL increase with an increase in frequency...

 

[LongBeach_Patriot]

I've always wondered what the aromatization is like on a 60-80 mg individual T shot...
I know I've seen my Estradiol rise to 340 pmol/l(92 pg/ml) 48 hours after 160 mg Shot....
Although my TRT doc said it was errored by the lab, because they are notorious for messing up Estradiol Tests.
He said that my Estradiol was closer to 200 pmol/l (54/pg/ml) on that test.
He won't give me another lab req. to run to verify....jerk!

My Estroadiol levels have never jumped. The highest I think was 40, and thats with a 200mg shot. They were actually super low which I know also isnt always good. Gotta find a good Endochrinologist to work with. My doc is conservative but he understands that everyones different and dosing/frequency is not the same for everyone.

 

[Megatron28]

My Estroadiol levels have never jumped. The highest I think was 40, and thats with a 200mg shot. They were actually super low which I know also isnt always good.

Was that at the peak or trough? Or did it hold steady throughout?

 

[LongBeach_Patriot]

It's the same amount of medication, but injecting once in a 10 day period, you might peak at 1500 and fall to 650.
Injecting half that amount every five days you might peak at 1250 and fall to 900.

Yes, the latter is better because it is more steady, but if your doctor no way wants you over 800 (all numbers hypothetical), then he will reduce your dose in the second case but not the first.

My doctor is aware that my peak is 1000-1200 and he won't bug out or cut me off as long as I don't use up my script faster than its due to be refilled. All signs point to it being advantageous to pin every 5 days. I'm just not sure if I should do 175/2=Roughly .45ml, or just do the full 200/.5ml. He had lowered my dose because my peak was high in his opinion. It actually only went u about 100ng/dl from the extra 25 mg. With 175 it maxes out around 1100, and 200 it was 1200. Really no big deal. I'm thinking of taking the full 100 every 5 days because the spike shouldnt be as high as if I were to take 200 in one shot.

Am I thinking about this right? Less single dose should cause a lower spike, therefore my peak should be lower with 100/5 than 200/10. I do understand that my script will run short this way but I'm picking up another bottle of Cyp NOT from the doctor.

Good info guys, thanks

 

[LongBeach_Patriot]

Was that at the peak or trough? Or did it hold steady throughout?

Here are my blood results for all the bloodwork I've gotten when both E2 and Test was checked simultaneously:

E2/Test

9.6/226- Trough
5.4/264- Trough
46.8/1030- Peak (2nd Cyp injection)
25/1033- Peak
18/257- Trough
21/216- Trough

This is in chronological order for the most part. It seems E2 jumped a little initially but then it leveled out after a couple shots.

 

[Mprtz]

This is false. Your peak WILL increase with an increase in frequency...

Huh? no it won't. Not for the same total amount of medication.

Consider an extreme example: 400mg once a month (low frequency), vs. 50mg every 3.5 days (high frequency)

Which has the higher peak?

 

[Mprtz]

My doctor is aware that my peak is 1000-1200 and he won't bug out or cut me off as long as I don't use up my script faster than its due to be refilled. All signs point to it being advantageous to pin every 5 days. I'm just not sure if I should do 175/2=Roughly .45ml, or just do the full 200/.5ml. He had lowered my dose because my peak was high in his opinion. It actually only went u about 100ng/dl from the extra 25 mg. With 175 it maxes out around 1100, and 200 it was 1200. Really no big deal. I'm thinking of taking the full 100 every 5 days because the spike shouldnt be as high as if I were to take 200 in one shot.

Am I thinking about this right? Less single dose should cause a lower spike, therefore my peak should be lower with 100/5 than 200/10. I do understand that my script will run short this way but I'm picking up another bottle of Cyp NOT from the doctor.

Good info guys, thanks

Yes, you are thinking about this right. It sounds like your doctor is actually measuring your peak vs. your trough. That's somewhat unusual (that's why I wrote 'typically') and in that case the opposite reasoning applies: injecting more frequently helps keep your peak within range.

 

[Virginian]

Definitely go to injecting every 5 days. There is too much variation between your peak and through. Your body is metabolizing the test very quickly - half-life of less than 5 days - which is faster than many people. You really need more frequent injections.

You might want to consider using small insulin needles like a 29 gauge half-inch needle. It fills slowly, but is less painful.

 

[STAUNCHED427]

Absolutely.

I tried E7D injections and it blew my e2 out the water and could not be controlled on 1mg Adex even.

I do every 3.5 days now, Sunday Mornings and Wednesday Nights... much better! You could probably get away with E4D, E5D at the most.