29 y/o, been sick for over a year, hormone labs just in, need help interpreting

[pg600rr]

29 y/o, been sick for over a year, hormone labs just in, need help interpreting

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So I have a very long story (which I wont go into right now) but starting last August 2011 I started having days where I'd feel general malaise, from there things went really downhill Feb. 12'. Prior to this I have always been healthy, good shape (6' 174lbs., very active), down to 154 lbs. now.

Since Feb. 12', I have prob seen about 30 specialists at boston area hospitals trng to diagnose me, tons of tests from every specialty, labs, biopsies, imaging, scopes, ATCH stim test, etc. etc.

Just recently I saw a urologist at mens health Boston and my lab results are posted below, I have yet to have a follow up.

Here are my symptoms (either currently or at some time during this ordeal):

-GI symptoms (nausea 24/7, gas, bloating, distention)
-hairloss
-mid/low back pain (dull)
-fatigue
-chest tightness
-finger tips get prune/wrinkle sporadically
-orthostatic tachycardia [diagnosed with POTS by Dr. Freeman @ Beth Israel]
-lost 18 lbs. 2/25-3/15, unable to gain any back
-body temp has been running very low, 96.5-97.2 (was never like this)
-not sleeping well (getting up sometimes 3x night to urinate 4/6/8am, waking early unable to fall back asleep)
-constant varying levels of dizzyness/lightheadedness
-feel very cold alot, especially hands and feet
-whole body feels very sick
-sporadic dull headaches (usually just above/behind eyes but varies)
-muscles in legs, arms upper back feel tight/achey from minute I wake (horrible feeling)
-usually have feeling of adrenline rush through body upon waking in the a.m.
-restricted breathing through nose (often have to sleep breathing only through mouth)
-sexual: trouble finishing, lowered libido, not getting nearly as erect as prior


Labs/Tests That Have Been Off:
-chest CT revealed nodule in left lung
-cyst on pole of kidney
-homocycteine has been elevated
-CK levels always very low
-folate low level of normal
-D has been low
-8% atypical lymphocytes
-mild postural orthostatic tachycardia (noted on several AFT's)
-sinus cyst shown in sinus CT
-various non-sepcific metabolic markers off on mito workup
-various lyme labs have shown bands

LABS FROM VISIT W/ Urologist (they dont have units or range w/ them yet):

Estradiol 20
FSH 4.8
LH 2.1
Progesterone <0.5
Prolactin 7.6
SHGB 40
Testosterone Total 295
PSA 0.3

From what research I have done, these #'s do not look good for someone of my age and the fact that I am not overweight and have never had any other medical problems...

Any input is greatly appreciated, really hoping I may have found an answer to some, if not all, the horrible symptoms I have been experiencing the last year!!

 

[ScottyB28]

After reading your post, I'm very sorry to hear of all your problems. I would go back to the doc ASAP and get on test injections once a week. I don't know if that will fix all your problems but I'll say a prayer that it'll heal you up my man. Stay strong brother.

 

[pg600rr]

After reading your post, I'm very sorry to hear of all your problems. I would go back to the doc ASAP and get on test injections once a week. I don't know if that will fix all your problems but I'll say a prayer that it'll heal you up my man. Stay strong brother.

hey, thanks for the well wishes, its been a tough road going from feeling great to where I am at... I am assuming from your suggestion my lab #'s look off to you? I really dont know much about this stuff, but from what little I've read, the test looks quite low for my age/body type, SHGB looks quite high and FH looks low... not sure what it all means

 

[ScottyB28]

I don't nearly as much as some of these guys on here. Hopefully they'll chime in and help you out.

 

[IMT staff]

Yes, anything below 300 ng/dl is pretty much considered low across the board, at any age.

With the SHBG where it is, in conjunction with the low TT number, your free roaming testosterone is also most likely low, which is more symptomatic than the low TT number.

 

[pg600rr]

Yes, anything below 300 ng/dl is pretty much considered low across the board, at any age.

With the SHBG where it is, in conjunction with the low TT number, your free roaming testosterone is also most likely low, which is more symptomatic than the low TT number.

I hope my urologist doc will see it the same way, I am interested to hear what he has to say, his group in general is thought to be at the cutting edge in this area of medicine and quite liberal with treatment.

I came across some calculation for free T using total T and SHBG and my resulting number was very low. Coupled with the low LH makes me think it might have something with the pituitary?

 

[halfwit]

I hope my urologist doc will see it the same way, I am interested to hear what he has to say, his group in general is thought to be at the cutting edge in this area of medicine and quite liberal with treatment.

I came across some calculation for free T using total T and SHBG and my resulting number was very low. Coupled with the low LH makes me think it might have something with the pituitary?

From what I've read, that's quite possible. I'd also get a metabolic panel done if you have a constant low body temp (thyroid issues possible) and a fasting blood glucose if you're urinating 3x a night. (Both are related to low testosterone.) Hope everything works out for you!

My .02c

 

[Megatron28]

I hope my urologist doc will see it the same way, I am interested to hear what he has to say, his group in general is thought to be at the cutting edge in this area of medicine and quite liberal with treatment.

I came across some calculation for free T using total T and SHBG and my resulting number was very low. Coupled with the low LH makes me think it might have something with the pituitary?

Low T coupled with lh and fsh in the below normal to low-normal range generally indicate secondary hypogonadism (i.e. pituitary).

 

[pg600rr]

Thanks for the replies. So I saw the urologist again, he wants to start treating with HCG only, says that I am secondary hypogonadism, did pituitary MRI and eveything was normal. THinks it may just be related to underlying chronic illness...just not sure what. Ideally he'd like to find the underlying illness, treat it and hopefully hormones would correct themself. However, since that has yet to be found he said just treating the hormones to get them into optimal levels might make me feel a bit better in the meantime.

Also saw a an endocrine after the urologist, wanted to double check my numbers in the a.m. fasting since the original draw posted above was @ 4pm.

Here are the numbers from that:
FSH 4.9 range 1-20
LH 2.1 range 1-9
T 410 range 241-827
SHBG 53.4 range 17-65

As you can see FSH/LH both were about the same as before...low. T is about 100 points higher (assuming since it was a 9am draw) although still not a good level for a 29 y/o and SHBG is actually quite a bit higher, making the free/bioavail T about the same or even a bit lower than the 4pm draw I had last week...