anyone here ever messed with DNP?

[snowpatrol123]

To the OP's question - DNP is nothing to be "messed with". If you have a super reliable source that you trust your life with, and monitor vitals very closely you can survive the sides but there are far milder/safer compounds I would exhaust first. I'm the exact kind of person that would probably use something like DNP if I felt it would help me accelerate my timeline towards achieving whatever goal, so I would never say never but before you go that route make sure it's the last resort.

Just IMO.

EDIT: You can find a lot of (fairly) balanced info/reviews re: DNP over on /r/steroids - I hope it's ok to post this here, not a source or selling anything so I don't see why not.
http://www.reddit.com/r/steroids/comments/1vse6r/dnp_update_so_this_is_what_hell_feels_like/

 

[DreDay187]

DNP-Related Fatalities
Fatalities from the intake of DNP, whether accidental or suicidal, have been reported since the turn of the twentieth century (Table 1). To date, there have been 62 published deaths attributed to DNP (Fig. 1). The largest publication of 36 deaths due to DNP was published in 1919 [6]. This was a study into the deaths in munition factories in Paris due to occupational exposure to DNP. It highlights the improvements made in the factory to prevent further deaths through simple measures such as ventilation, personal protective equipment and better hygiene. This combined with changes in legislation brought the death rate down from 16.3 per 10,000 t of DNP handled/produced to 1.2 per 10,000 t.

During the 1930s, reported DNP-related fatalities were all individuals who had taken it for weight loss [46, 47, 51, 56, 57, 61, 67, 71]. After the 1930s, there have only been two During the 1930s, reported DNP-related fatalities were all individuals who had taken it for weight loss [46, 47, 51, 56, 57, 61, 67, 71]. After the 1930s, there have only been two fatalities in the remainder of the twentieth century [15, 68]. One related to deliberate ingestion of DNP [68] and the other was where an individual accidentally ingested a liquid he thought to be grape juice, but in fact contained derivatives of DNP [15]. This further decline in fatalities may reflect the labelling of DNP as ***8216;extremely dangerous and not fit for human consumption***8217; by the US Food and Drug Administration in 1938.

Over the last decade, from 2001 to 2010, there have been 12 deaths related to exposure to DNP. These fatalities have been linked to deliberate overdose [4, 22, 69], accidental toxicity associated with use by bodybuilders or for weight loss [21, 28, 72***8211;75] and accidental occupational exposure [33]. This resurgence in reported fatalities may reflect the increased availability of DNP over the internet, marketed particularly towards bodybuilders.

Preceding death, the patient is often profoundly hyperthermic and there may be associated methaemoglobinaemia. Death is usually secondary to massive cardiovascular collapse. There have been frequent reports of a rapid (within minutes) onset of generalised rigidity after death [6, 11]. This profound muscle rigidity has also been seen to happen before death making mechanical ventilation very difficult [21]. This early onset of generalised rigidity after death has been attributed to the release of calcium from the cytosol due to the depletion of ATP [22].

2,4-Dinitrophenol (DNP): A Weight Loss Agent with Significant Acute Toxicity and Risk of Death


^^^the study even mentions DNP has a small therapeutic index!!!

 

[riprockwell]

I get what you guys are saying but from a common sense stand point, I just don't see the point. A lot of guys mention using it and a lot of guys don't have amazing results from it. Not saying you haven't Pedzilla but I just haven't seen great results with others. The fact the stuff is used in explosives and herbicides just doesn't sit well with me. However, the main issue I have with it is that there is not a lot of room for error like Halfwit said. Especially seeing dudes on here all the time thinking more is better, I could see that as a huge problem. Are there worse things out there?? Perhaps. However, like I said, most users lose 1 pound per day. Hopefully they don't feel like death like I did and I hope they don't have an extreme allergic reaction. When have I seen anyone shoot testosterone or pop a T3 pill and get a 103 degree fever, break out in a rash, and have their throat close??

I know there is some scare tactics on a lot of compounds but I just don't personally see the need for people to take the stuff. Even if the average user loses 12lbs in 12 days, most of the time that number is skewed because how many people are going to drink gallons of water on DNP besides you?? Most people don't even get half a gallon in per day much less "gallons" of water. Like I said, once I was off the DNP, I put back on some pounds so the total weight loss was like 6-8 lbs in 12 days. I can get pretty much similar results on a Keto. This is my personal experience.

 

[Mrrippedzilla]

Dreday: Thank you for the welcome back & for finding the article I was referring too

riprock:
Usually the reason people don't see the results they wanted is due to water retention or using DNP as an excuse to binge. The retention goes away after a week or so but most people assume the DNP didn't work, so they give up and binge, which is why I suspect we never see "after" photos. As for the poor diet discipline, DNP is brilliant but it wont offset you going 2000 calories over maintenance while your on it (carb cravings is a notorious side effect).
I agree that the side effects are a pain if you have any sort of a social life, I was lucky enough to take time off work so I could cope with the sweating (and smell). It really is a choice between social life or DNP, not both - I suspect this is also why you don't see people using dnp for long periods of time (rather than any long term side effects).

I do agree with you that you don't "need" DNP, I mentioned that the scare tactics are a GOOD THING to put the public off because, frankly, they (and any newbies on here) can't be trusted with DNP. The is no play room - simply going from 200 - 400mg can cause life threating problems. The public generally can't be bothered to focus with diet/training and see DNP as a miracle. They ignore the sides and the warnings (drink water, etc) & they die - simple as that. I also suspect this is the major reason doctors stopped prescribing DNP after the 30's: can you trust your patient to drink that much water? No. If the patient is completely idiotic and dies, who will get the blame? The doctor.
However, for a bodybuilder whos late on his contest prep/a fitness model out of shape with a shoot in 4 weeks - DNP is a career saver. These are people who are already dialed in with the fundamentals to fat loss. The problems are more to do with how poorly educated people are on DNP, not with DNP itself.

As for comparing your keto results to DNP ....you likely lost 6-8 lbs of PURE FAT in 12 days on DNP, on keto maybe 2lbs of the 6-8 was fat in the same time frame. As I said before, DNP results cannot be compared to anything else.

 

[DreDay187]

Dreday: Thank you for the welcome back & for finding the article I was referring too

Not a problem brother. I learned quite a few diet related things during our interactions/debates so I hope you stick around brother.

 

[riprockwell]

Dreday: Thank you for the welcome back & for finding the article I was referring too

riprock:
Usually the reason people don't see the results they wanted is due to water retention or using DNP as an excuse to binge. The retention goes away after a week or so but most people assume the DNP didn't work, so they give up and binge, which is why I suspect we never see "after" photos. As for the poor diet discipline, DNP is brilliant but it wont offset you going 2000 calories over maintenance while your on it (carb cravings is a notorious side effect).
I agree that the side effects are a pain if you have any sort of a social life, I was lucky enough to take time off work so I could cope with the sweating (and smell). It really is a choice between social life or DNP, not both - I suspect this is also why you don't see people using dnp for long periods of time (rather than any long term side effects).

I do agree with you that you don't "need" DNP, I mentioned that the scare tactics are a GOOD THING to put the public off because, frankly, they (and any newbies on here) can't be trusted with DNP. The is no play room - simply going from 200 - 400mg can cause life threating problems. The public generally can't be bothered to focus with diet/training and see DNP as a miracle. They ignore the sides and the warnings (drink water, etc) & they die - simple as that. I also suspect this is the major reason doctors stopped prescribing DNP after the 30's: can you trust your patient to drink that much water? No. If the patient is completely idiotic and dies, who will get the blame? The doctor.
However, for a bodybuilder whos late on his contest prep/a fitness model out of shape with a shoot in 4 weeks - DNP is a career saver. These are people who are already dialed in with the fundamentals to fat loss. The problems are more to do with how poorly educated people are on DNP, not with DNP itself.

As for comparing your keto results to DNP ....you likely lost 6-8 lbs of PURE FAT in 12 days on DNP, on keto maybe 2lbs of the 6-8 was fat in the same time frame. As I said before, DNP results cannot be compared to anything else.

Reps for you on this post man. I definitely see your point and the more I think about it and especially after reading the article Dre posted, I can see your side. I guess I am just used to 95% of the guys on here not being at the level that most people should be at when touching the stuff. Hell even lately a lot of the guys thinking about DNP don't remotely have a good diet locked in. I do have a national bodybuilding buddy who has cycled DNP fine after several shows but myself, it brought me to a dangerously high temperature. After the fact, I learned that some guys have allergic reactions and that you should take Benadryl with it and it will stop the reactions 90% of the time. I wish I would have known that at the time I took it because my throat was swelling shut, my temp was 103 and I was feeling like I was going to die. lol. I am just basing it on my own personal experience but it is good to see someone like yourself who has run it safely and effectively and has lost a good amount of fat with it. Most of the guys I have seen haven't lost much which is why I rarely recommend it. lol. How much do you run when you do?? I got up to 400mg per day. I was weighing 200lbs at the time. My buddy who competes is around 240lbs and was up as much as 800mg per day. I still think he was crazy to use that much man. He never had problems on it other than the uncontrollable sweats.

 

[Mrrippedzilla]

Dnp, like all supplements, should be used in addition to proper diet & training not as a substitute. The general public are clueless when it comes to dieting/training for fat loss and, sadly, all dieters have a mentality of "more is better". If i cut my calories more, if I exercise more, If I take more dnp, etc, etc - this approach always ends in failure (giving up and binging or for dnp even worse).
I started my dosing at 100mg and slowling increased it to 300mg per day, my weight flunctuates between 135-155 so anything over that was unnecessary. Generally I use concilliator's recommendation of between 2-6mg/kg - starting on the low side and working up.
The side effects really depend on the individual - you always get the classics like sweats, fatigue, cravings, etc. Some people (like you lol) react very badly to it but others (your buddy) are fine. For me, the carb cravings were the worse - I had a mental image of carbs all the time, felt like I was going insane .