Can anyone shed some light on leptin?
- Thread starter stepweed
- Start date
Yes, well as a form of weight maintenance at least. If you look at the below articles, they all say the same thing. I guess this isnt common knowledge so the public isnt demanding it.
• Mechanisms of Weight Regain following Weight Loss (4/16/2013)
ncbi.nlm.nih.gov/pm...
• Leptin reverses declines in satiation in weight-reduced obese humans (1/11/2012)
ncbi.nlm.nih.gov/pm...
• Long-term persistence of adaptive thermogenesis in subjects who have maintained a reduced body weight (7/6/2008)
ajcn.nutrition.org/cont...
• Low-dose leptin reverses skeletal muscle, autonomic, and neuroendocrine adaptations to maintenance of reduced weight. (12/1/2005)
ncbi.nlm.nih.gov/pm...
• Leptin reverses weight loss–induced changes in regional neural activity responses to visual food stimuli (7/1/2008)
ncbi.nlm.nih.gov/pm...
• Low dose leptin administration reverses effects of sustained weight-reduction on energy expenditure and circulating concentrations of thyroid hormones. (5/8/2002)
ncbi.nlm.nih.gov/pu...
• Effects of reduced weight maintenance and leptin repletion on functional connectivity of the hypothalamus in obese humans. (3/21/2013)
ncbi.nlm.nih.gov/pm...
• Revisiting leptin’s role in obesity and weight loss (7/1/2008)
ncbi.nlm.nih.gov/pm...
Mrrippedzilla
MIA - PM only
I'm currently experimenting with Leptin so I'll shed some light on this...
- Its VERY expensive.
Real leptin from a legitimate supplier will cost you the equivalent of $200-300 for a 200mcg vial.
Now consider the fact that the studies dosed leptin at 10-30mcg/kg and you will see just how expensive this is going to be.
For example, at the moment if I was to use leptin daily it would end up costing me $600 PER DAY.
- There is NO set dosing protocol.
Although the 10-30mcg/kg dosing is what has been used in general, these studies included obese individuals - so your going to have to do a lot of experimenting with the dose.
Your also going to have to spend a lot of money on bloodwork to see where your leptin levels are (since they need to be above a specific point to reap the benefits) and make dosing adjustments accordingly.
- Its only useful for already dieted down individuals.
If your simply looking for another compound to help lose weight, then your wasting a lot of money if Leptin is the route you opt to go for.
Considering all of this, for most people Leptin simply isn't a viable option
- Its VERY expensive.
Real leptin from a legitimate supplier will cost you the equivalent of $200-300 for a 200mcg vial.
Now consider the fact that the studies dosed leptin at 10-30mcg/kg and you will see just how expensive this is going to be.
For example, at the moment if I was to use leptin daily it would end up costing me $600 PER DAY.
- There is NO set dosing protocol.
Although the 10-30mcg/kg dosing is what has been used in general, these studies included obese individuals - so your going to have to do a lot of experimenting with the dose.
Your also going to have to spend a lot of money on bloodwork to see where your leptin levels are (since they need to be above a specific point to reap the benefits) and make dosing adjustments accordingly.
- Its only useful for already dieted down individuals.
If your simply looking for another compound to help lose weight, then your wasting a lot of money if Leptin is the route you opt to go for.
Considering all of this, for most people Leptin simply isn't a viable option
Last edited:
Megatron28
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