Depression on test cycle?

AlaskanGriz

New member
Hey I'll give a little background info on myself. I'm 27 and currently 195lbs 6'1 and roughly 16 percent body fat. I started a test e cycle on July 10th, 250mg x2 week along with Hcg 250ius x2 week with aromasin 10mg Ed. I started the aromasin 10mg 10-14 days into the cycle e3d and moved it to every other day because of water retention and some slight elevation of BP. Last week I moved the aromasin up to Ed 10mg and seemed to work great as far as BP water retention and feeling, but I'm wondering if I crashed my e2?

This last week I've been really stressed, about to start a new job which happens to be my career choice and have been slightly depressed, have anxiety and been lethargic and today nauseated. Tired in the gym but making great gains. I'm going to get some blood work in the next day because I know that's the only definitive proof. Really I guess I'm looking for some suggestions and possible support? I've thought about stopping the cycle this last week because of all these changes going on currently in my life aka career and moving etc. I'm also concerned about my pct, I've heard all the sides of clomid. Being already slightly depressed is it just going to get worse? Any other options if clomid is unbearable? I'll also be running nolva.

Dunno if it's any significance but I also take adderall which I've been on many years and clonidine for heart rate by increase. I've slightly increased my clonidine dose while on cycle to help regulate my blood pressure. Looking for some input from some experience users suggestions etc. maybe I just crashed my e2 and I'm overthinking everything?
 
A blood test costs ~50 bucks. The results are priceless.

I'd head over to privatemdlabs.com and order the female hormone panel (menopause panel) and KNOW what's going on. I'm thinking your estradiol is too HIGH, not low. But that's the problem with estradiol; high and low values mimic each other to a great extent.

My .02c :)
 
Thanks for responding so quick. I was considering holding a dose of the aromasin but after your post maybe not? My shoulders were aching something fierce today and I've been drinking a lot of water and not retaining any it seems as much as I've been peeing. But your right the sides don't tell all. I'll be getting blood work tomorrow. You think I should take my normal 10m aromasin dose in the am tomorrow?
 
Thanks for responding so quick. I was considering holding a dose of the aromasin but after your post maybe not? My shoulders were aching something fierce today and I've been drinking a lot of water and not retaining any it seems as much as I've been peeing. But your right the sides don't tell all. I'll be getting blood work tomorrow. You think I should take my normal 10m aromasin dose in the am tomorrow?

You can hold off on the aromasin until you get your results. If you're crashed, it will help you come back up - and if you're high, it won't skyrocket up as aromasin is a suicidal inhibitor.

The main reason I suspect it's high is that aromasin doses usually START at 12-25mg ED, which is significantly higher than where you've started. Granted, some folks respond more than others, so it potentially could have been too much too.
 
You can hold off on the aromasin until you get your results. If you're crashed, it will help you come back up - and if you're high, it won't skyrocket up as aromasin is a suicidal inhibitor.

The main reason I suspect it's high is that aromasin doses usually START at 12-25mg ED, which is significantly higher than where you've started. Granted, some folks respond more than others, so it potentially could have been too much too.

I think with dosages its a YMMV. Some people need it ED, some EOD, some twice a week. Which is why we all get pre and mid cycle BW. Pick a protocol and stick with it, get BW and adjust from there.
 
You can hold off on the aromasin until you get your results. If you're crashed, it will help you come back up - and if you're high, it won't skyrocket up as aromasin is a suicidal inhibitor.

The main reason I suspect it's high is that aromasin doses usually START at 12-25mg ED, which is significantly higher than where you've started. Granted, some folks respond more than others, so it potentially could have been too much too.


Estradiol 41.8 (range 7.6-42.6pg/ml)
AST 50.0 (range 0-40 IU/L)
ALT 50.0 (range 0-44 IU/L)

Looks like 10mg of aromasin a day is keeping me in high range, are these liver enzymes anything to be concerned about?
 
Estradiol 41.8 (range 7.6-42.6pg/ml)
AST 50.0 (range 0-40 IU/L)
ALT 50.0 (range 0-44 IU/L)

Looks like 10mg of aromasin a day is keeping me in high range, are these liver enzymes anything to be concerned about?

Nothing to be concerned about, no. You might want to run some NAC though (600 - 1200mg daily.) Fix those values right up.

I wouldn't exactly say your e2 is high, but some guys feel better with it down around 20-30pg/ml. You could up the aromasin to 15-20mg a day and see where that puts you.
 
Should it be fine just buying some NAC from Walgreens? Guess I'll keep the ED dosing, I can't imagine the small amount of estro causing me to feel so down and lethargic? Definitely stressed about new job probably doing the most damage atm. Thanks for your input prince.
 
NAC from walgreens should be fine.

Psychological issues can have a pretty big bearing. You sound like your prone to anxiety, but then again I don't know a thing about you aside from a couple posts. Do you get anxious often? You are making a lot of big life changes so that would totally make sense.

If you've only been on that dose a week you could probably leave it, e2 might still come down a bit more. It's not a large difference but I have heard of guys who feel like shit 40-50, and dropping to 20-30 alleviates it. Personally I can't tell much difference from 10-60 but that's me.

The increase in clonidine could be it? Who knows, there's so many variables. The fact is any medications can produce a whole range of side effects, and changing in doses can make things hard to narrow down.

Where's your TT at btw? Is it possible you have underdosed gear? How's your gains/weight/strength etc.?
 
Estradiol 41.8 (range 7.6-42.6pg/ml)
AST 50.0 (range 0-40 IU/L)
ALT 50.0 (range 0-44 IU/L)

Looks like 10mg of aromasin a day is keeping me in high range, are these liver enzymes anything to be concerned about?

That's actually about perfect as the non-sensitive panel overshoots by about 10pg/mL. Looks like you found a good dose. Prince covered the NAC portion and does pose a good question. What did TT come back as? >1500 is common for the standard test results.

I doubt it's low, given your estradiol - but always a good thing to rule out. Also, you have to remember that hormones can and do amplify emotions, so if you're sad - you can get REALLY sad. (although the dopamine uptake increase usually keeps folks mellow and happy)
 
That's actually about perfect as the non-sensitive panel overshoots by about 10pg/mL. Looks like you found a good dose. Prince covered the NAC portion and does pose a good question. What did TT come back as? >1500 is common for the standard test results.

I doubt it's low, given your estradiol - but always a good thing to rule out. Also, you have to remember that hormones can and do amplify emotions, so if you're sad - you can get REALLY sad. (although the dopamine uptake increase usually keeps folks mellow and happy)

Damn, seems I still have some learning to do lol. I figured that was the sensitive assay because the lower range was so low. Thanks Half :)
 
NAC from walgreens should be fine.

Psychological issues can have a pretty big bearing. You sound like your prone to anxiety, but then again I don't know a thing about you aside from a couple posts. Do you get anxious often? You are making a lot of big life changes so that would totally make sense.

If you've only been on that dose a week you could probably leave it, e2 might still come down a bit more. It's not a large difference but I have heard of guys who feel like shit 40-50, and dropping to 20-30 alleviates it. Personally I can't tell much difference from 10-60 but that's me.

The increase in clonidine could be it? Who knows, there's so many variables. The fact is any medications can produce a whole range of side effects, and changing in doses can make things hard to narrow down.

Where's your TT at btw? Is it possible you have underdosed gear? How's your gains/weight/strength etc.?

Definitely prone to anxiety I take klonopin prn which is pretty seldom. And since you mention it I bet the clonidine increase is probably not helping my energy any and probably affecting my mood some. The gear is definitely legit all EP, making great gains up 15 plus lbs more vascular making great gains on my lifts and feel like I cutting bf feeling more lean. Labs just showed >1500ng/dL both FSH and LH are <0.2. Making great progress in gym except for last couple days, my appetite has been a bit less so I've had problems eating as much. I'm thinking this is mostly psychological and I get got myself a little twisted. Thanks a lot for the info, your reassurance and advice definitely making me feel better. Thinking I'll stick with the ED 10mg dosing since I've only been on it one week. Maybe check bloods again closer to end of cycle. Should I run this aromasin up until PCT or throughout it? Current pct plan clomid 50/50/50/50 nolva 20/20/20/20 with Hcg running up till 5 days before PCT start.
 
I'd stop the asin the day before you start PCT. Aromasin is the one AI that can be run during PCT, but I wouldn't recommend it unless you're hypersensitive to estradiol (gyno issues for example) as it does slightly interfere with the process of returning to homeostasis.
 
I'd stop the asin the day before you start PCT. Aromasin is the one AI that can be run during PCT, but I wouldn't recommend it unless you're hypersensitive to estradiol (gyno issues for example) as it does slightly interfere with the process of returning to homeostasis.

Ahh right on man, great advice makes sense also will run it up till pct. Is there any other alternative to clomid out there if it ends up causing any unbearable sides? What about supplements pct and hcgenerate N2guard? Any legitimacy to these supps? Been hard to find non biased opinions etc. thx halfwit ***128077;***127995; very helpful.
 
I suffer from anxiety and when estradiol is high it flares up.


Interesting, I've noticed I feel better the days I don't take the aromasin on an eod dosing, think it may be related to the actual AI. Hoping it gets better with a consistent dosing now that thetest is built up in my system at consistent dose. Still having good days and some not so good.
 
Ahh right on man, great advice makes sense also will run it up till pct. Is there any other alternative to clomid out there if it ends up causing any unbearable sides? What about supplements pct and hcgenerate N2guard? Any legitimacy to these supps? Been hard to find non biased opinions etc. thx halfwit ***128077;***127995; very helpful.

You can try raloxifene with nolva, but clomid/nolva is optimal.

Supplements are just that - supplements. If you're dealing with hormones, NOTHING can replace the DRUGS that are required. This counts for AI's, HCG, and SERMs.
 
You can try raloxifene with nolva, but clomid/nolva is optimal.

Supplements are just that - supplements. If you're dealing with hormones, NOTHING can replace the DRUGS that are required. This counts for AI's, HCG, and SERMs.

Excellent info halfwit will look into raloxifene, just trying to have all grounds covered for best recovery. Any recommendations for sex drive during pct other than cialis? Old lady is worried ***128514; haha
 
Excellent info halfwit will look into raloxifene, just trying to have all grounds covered for best recovery. Any recommendations for sex drive during pct other than cialis? Old lady is worried ***128514; haha

Cialis doesn't do anything for your sex drive. It simply increases blood flow by inhibiting PDE5. So it will help you get & stay hard, that's about it.
Not much you can do for actual sex drive when your hormones are in the shitter. Just stay on Cialis so you can perform & wait it out :)
 
Back
Top