Dialing in E2

[TR90125]

Last week I had my E2 tested, primarily because I was feeling very lethargic and borderline depressive and suspected my E2 was low.

In a recent follow up with Chip, my Aromatase inhibitor (AI) was dialed back to 1 mg Adex E5D. However, I found myself bothered by the fact that my total estrogens were on the high side, so I took an additional dose of Adex. Within 24 hours I felt like I was hit by a freight train and all I wanted to do was rest.

My first E2 test came back at 13.4 pg/mL after taking 1 mg of Adex twice in 48 hours.

Yesterday I went back for another round of E2 testing and had not taken any Adex for 6days, my last does being 1 mg on Tuesday of last week. I went in to get tested primarily because I felt my mood was elevated and I felt good, like you would hope to feel on Hormone Replacement Therapy (HRT).

My E2 level came back at 45.7 pg/mL.

I did learn a couple things through this. I obvioulsy do better on the upper end of the E2 Scale, although I am going to try and slowly bring my level down to see how low I can go before I feel like shit again.

The other thing is to listen to Chip. The end result of all this is I am back on the exact dose and frequency Chip suggested to begin with. I guess I got too hung up on numbers and not how I was actually feeling.

If I continue to feel good, I will probably get a follow up E2 test within 2-3 weeks to see how 1 mg E5D effects my level.

 

[Packgus]

how has libido been? how has erections been?

I ask because I am battling the same issues with trying to dial in my estrogen. I have issues with great libido but not so good erections. I cant figure it out.

 

[TR90125]

how has libido been? how has erections been?

I ask because I am battling the same issues with trying to dial in my estrogen. I have issues with great libido but not so good erections. I cant figure it out.

Great question.

My libido has felt stronger than my erections have lately. I am hoping if I can find a happy medium I can keep my mood, libido and have strong erections. Right now, I would say my mood is the best out of the three, which is a good starting point. I am hoping I can get down to 30 or so and still feel good and have improved libido and erections.

 

[JKB]

I feel much better on the higher end of the scale myself. How long did it take you to get your estro back up to that level after it was tested at 13.4??

 

[TR90125]

I feel much better on the higher end of the scale myself. How long did it take you to get your estro back up to that level after it was tested at 13.4??

I went exactly 6 days without taking my Aromatase inhibitor (AI). I was at 13.4 after taking 1mg twice within 48 hours. I am hoping 1mg E5D keeps me in the 30 range. Time will tell.

I took 1 mg of Anastrozole today after seeing my results.

 

[cjw2021]

adex can be a finicky drug. for me letro twice a week at 2.5mgs per shot does it good.

 

[JKB]

TR90125 I noticed on your other thread you had also tried taking you Aromatase inhibitor (AI) e7d. How did you feel at that dose? Did you feel better than e5d?
I feel so much more better cutting back my Aromatase inhibitor (AI) to e5d. I was thinking about trying out e7d but wanted to get your opinion on how you felt

 

[TR90125]

TR90125 I noticed on your other thread you had also tried taking you Aromatase inhibitor (AI) e7d. How did you feel at that dose? Did you feel better than e5d?
I feel so much more better cutting back my Aromatase inhibitor (AI) to e5d. I was thinking about trying out e7d but wanted to get your opinion on how you felt

I don't think I actually did it E7D and I may have meant E5D, so basically a typo. The longest I have gone without taking my Aromatase inhibitor (AI) was 6 days. The week prior I took two 1 mg doses within 48hrs.

I felt great after 6 days, but was a little concerned my E2 was 45.7. Based on that, it seems E5D should be the ticket.

I took 1 mg yesterday and felt foggy just for the first half of the day today, but I am already out of it and feeling back to good. Adex seems like a real MF'er to me.

Also, I injected T today for the second time on my new E3D schedule. I'm not sure if or how that will effect estrogen, but I seem to respond well to it so far, but it's early.

 

[JKB]

How much mg of Aromatase inhibitor (AI) are you taking? I am on 1mg Anastrozole e5d. lol I agree with you on the Aromatase inhibitor (AI) being a M'fr. I can even sleep the nights I take it.

 

[TR90125]

me too.

 

[JKB]

Good deal! Thanks for the input bro. Much appreciated and I feel more comfortable knowing that I am not the only one that feels better on a higher e level.

 

[TR90125]

For me the difference between the low end and the high end of E2 is quite amazing. On the low end I might as well be in a coma.

 

[David1963]

My doctor has me cutting the 1 mg Anastrozole tablets into quarters. (Yes....very small pieces.) He's prescribed 0.25mg 3 times a week, but I think I need more as my e2 is still above 30. If you're having negative reactions to 1 mg at a time, perhaps you can spread it out over 2 or more days too? I never notice any difference between days I take a quarter tab and days I don't.

 

[JKB]

My doctor has me cutting the 1 mg Anastrozole tablets into quarters. (Yes....very small pieces.) He's prescribed 0.25mg 3 times a week, but I think I need more as my e2 is still above 30. If you're having negative reactions to 1 mg at a time, perhaps you can spread it out over 2 or more days too? I never notice any difference between days I take a quarter tab and days I don't.

I was thinking about taking .5mg anastrozole twice a week to see how it feels. But how do you cut those small tablets to four pieces. I dont even know how I would cut it to two pieces.

 

[EnhancedAthlete]

Easy! Buy a pill cutter. Any CVS or Walgreens sells them. They are usually located near the pharmacy. I use one for my finasteride pills to cut accurately into quarters.

 

[tuscans]

I use this method:

For each tab use 1ml of vodka, shake and dissolve. A graduated dropper would be handy. In any case, you need to count the drops per ml and calculate drops per dose.

If filler of pills leaves a sludge, shake before dispensing and counting drops per ml. The anastrozole will be totally in solution.

If that works for you, you can make larger batches.

All droppers are different so calculate with the dropper you have.


With 28 drops per ml, if you take 8 drops EOD, that is 8 drops/dose X 3.5 doses/week = 28 drops/week = 1mg/week.

So divide your drops per ml by 3.5 and that is your dose.

 

[woobs]

Last week I had my E2 tested, primarily because I was feeling very lethargic and borderline depressive and suspected my E2 was low.

In a recent follow up with Chip, my Aromatase inhibitor (AI) was dialed back to 1 mg Adex E5D. However, I found myself bothered by the fact that my total estrogens were on the high side, so I took an additional dose of Adex. Within 24 hours I felt like I was hit by a freight train and all I wanted to do was rest.

My first E2 test came back at 13.4 pg/mL after taking 1 mg of Adex twice in 48 hours.

Yesterday I went back for another round of E2 testing and had not taken any Adex for 6days, my last does being 1 mg on Tuesday of last week. I went in to get tested primarily because I felt my mood was elevated and I felt good, like you would hope to feel on Hormone Replacement Therapy (HRT).

My E2 level came back at 45.7 pg/mL.

I did learn a couple things through this. I obvioulsy do better on the upper end of the E2 Scale, although I am going to try and slowly bring my level down to see how low I can go before I feel like shit again.

The other thing is to listen to Chip. The end result of all this is I am back on the exact dose and frequency Chip suggested to begin with. I guess I got too hung up on numbers and not how I was actually feeling.

If I continue to feel good, I will probably get a follow up E2 test within 2-3 weeks to see how 1 mg E5D effects my level.

I am going through the same thing. I was taking 1mg Adex E4D, got E2 sensitive labs done and showed my E2 at 37. My libido was actually pretty good here with strong morning wood. However like you I got concerned with the number and thought it would be even better at like 20-25.

So on my scheduled Adex dose day I took 1.5mg and crashed!! Same feeling, lethargic, no libido at all and achy joints. I have not taken any Adex in 8 days and still feel out of whack. I have morning wood, but libido still sucks and my joints still ache.

I probably should have just stuck with my protocol of 1mg E4D.

My regimen is:
125mg Test Enanthate E4D
350 IU Human Chorionic Gonadotropin (HCG) day after test shot
1mg Adex day of test shot (E4D)

Gonna get labs done on Monday

 

[TR90125]

I can totally relate. I'm still adjusting things slightly. There's a lot of moving parts to this deal, but I do know that under my current protocol, my mood is right where I want it most of the time. I took my last Adex Tuesday and was a little lethargic for about a half day. My mood has been awesome since then, but I noticed this morning my wood was not all there during sex. I am supposed to take my next Adex tomorrow, 1 mg.

Here's my current protocol

Test cyp 125 E3D
Adex 1mg E5D
HCG 200 IU E3D
Danazole 25mg daily
Cytomel 25mcg daily

Today was my third test injection on an E3D schedule and I feel like I am responding to it very well.

I am starting the Human Chorionic Gonadotropin (HCG) on an E3D schedule as of tomorrow, before that I was 250 IU E5D.

The Danazole has been great, no worries there.

Cytomel taken 50mcg daily was my original protocol, but I stopped taking it after my first week primarily to focus on the getting my mood where I wanted it and I wasn't sure if Cytomel was impacting my mood, so I took a break primarily to eliminate it as a variable, so to speak.

I have been on 3J's nutrition plan for 5 weeks and started taking 25mcg of Cytomel on Monday. My fat loss seems to have increased and I am still adding weight to my lifts at the gym, so it's all good for now.

At this point, I certainly do not want to increase my Adex dosage, however, I am considering changing it from 1 mg E5D to 1/2 mg E3D to line up with the rest of my protocol. It seems like my current Adex dosage is just a little too much on day one, as I do notice some lethargy, and by day four my wood is starting to subside. Based on my previous reactions to Adex, I am reluctant to take 1mg E3D, but it may come to that. Time will tell.

The bottom line is, I feel like I am really close to 100% dialed in and frankly, even is this is as good as it gets, it's pretty damn good.

 

[TR2838]

Sounds like you got a handle on your regiment.. Personally, I would go by mood also.. If the wood is a little weak, pop a cialis here and there.
How's the diet going?

 

[TR90125]

Sounds like you got a handle on your regiment.. Personally, I would go by mood also.. If the wood is a little weak, pop a cialis here and there.
How's the diet going?

The thing with mood is it's with you 24/7, so yes, it's my top priority. Prior to Hormone Replacement Therapy (HRT) I was always moody, easily aggravated and sometimes depressed so being in a good or really good mood most of the time is huge!

The diet is going very well. I will post a more detailed update in my 3J thread.