does t3 make difference in fat loss on tren.

SonOfZeu$

SonOfZeu$

Never Satisfied
So im just wondering if t3 does anything crazy for you when ur on tren. My diet is clean, my cycle is tren,test,prop. Just wondering if t3 is worth taking with this cycle. I dont plan on going past 40-50mcg i think. any advice
 
MeatHead96 said:
I've run 25mcg on tren a couple times. No need to go high on the dose. It would be a good addition to a recomp
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i gotta give u a rep bro, because no never replies to the advice i try to get haha. Well then I'll run the .40mg just till week 5 and then taper down to 25mcg.

Hey bro I have another question, im not shedding hair now, but i had dutast, have you ever used it or any product similar to it>?

And hows your cycle going
 
From a medical stand point, I dont see why it would make a difference. As long as you are not passing the point where the t3 is beating out your metabolism and you get to the point where protein is being brokendown for energy.
 
T3 is highly catabolic no matter what people say. Of course dosage dependent! Some say that 25mcg is just too low for a ED dosage since that's what aprox what your own body produces per day.
 
SonOfZeu$ said:
i gotta give u a rep bro, because no never replies to the advice i try to get haha. Well then I'll run the .40mg just till week 5 and then taper down to 25mcg.

Hey bro I have another question, im not shedding hair now, but i had dutast, have you ever used it or any product similar to it>?

And hows your cycle going
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Thanks bro, 25mcg is good on tren because tren is slightly suppressive to the thyroid. 25mcg is pretty much a replacement dose and I wouldn't worry about catabolism at this dose while on tren. Never run dutast, I've heard shitty things about sides but never used it. I just shave my head. I accept that I'll be bald lol. My cycles good so far...I'm about two weeks into the tren/mast and just added in Anavar (var) a couple days ago at 80mg a day. Let the good times roll :)
 
MeatHead96 said:
Thanks bro, 25mcg is good on tren because tren is slightly suppressive to the thyroid. 25mcg is pretty much a replacement dose and I wouldn't worry about catabolism at this dose while on tren. Never run dutast, I've heard shitty things about sides but never used it. I just shave my head. I accept that I'll be bald lol. My cycles good so far...I'm about two weeks into the tren/mast and just added in Anavar (var) a couple days ago at 80mg a day. Let the good times roll :)
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thanks and yea i hear mix reviews about it, but if i start shedding ill start using it, i bought already so fuck it.
 
AndreiD said:
T3 is highly catabolic no matter what people say. Of course dosage dependent! Some say that 25mcg is just too low for a ED dosage since that's what aprox what your own body produces per day.
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The man speaks the truth! Why suppress your thyroid for a replacement dose? Go with t4 it's better, especially with GH :)
 
Sworder said:
The man speaks the truth! Why suppress your thyroid for a replacement dose? Go with t4 it's better, especially with GH :)
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I hear this too often and yeah it can be catabolic at high ass doses that people take but 25mcg on cycle is not going to be a catabolic. It will increase protein turnover rate allowing your body to process more of it. Tren is slightly suppressive to the thyroid so t3 is an excellent addition to a tren cycle. Yes, 25mcg is what is considered a replacement dose but that's assuming your thyroid is functioning at 100 percent which probably isn't the case, especially on tren.
 
MeatHead96 said:
I hear this too often and yeah it can be catabolic at high ass doses that people take but 25mcg on cycle is not going to be a catabolic. It will increase protein turnover rate allowing your body to process more of it. Tren is slightly suppressive to the thyroid so t3 is an excellent addition to a tren cycle. Yes, 25mcg is what is considered a replacement dose but that's assuming your thyroid is functioning at 100 percent which probably isn't the case, especially on tren.
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T3 and T4 are always catabolic, it breaks down. It may affect the protein turnover rate but most studies I see have thyroxine (T4) > tri-iodothyronine (T3). I used T3 twice, didn't like it. Also makes you suffer from the suppression which usually kicks back in PC and it becomes more and more catabolic and effects your nitrogen balance in a bad way(read breaks muscle tissue down). Trenbolone increases nitrogen balance so the T3 is working against it, I don't see any reason to use it at a small dose for an extended period. I would use it at high dose 100mcg with a lot of tren and a lot of protein. The 25mcg is going to serve as a replacement for your endogenous production and to be quite honest, I don't really see a good reason for t3. t4 particularly included with growth hormone will increase nitrogen balance is a killer combo.

Not trying to argue with you, if you have some information in regards to this it would help clear this issue for me and lot of other guys. This is just my opinion and how I have interpreted most of what I have read. I think the last study on the list kinda kills it though. ;)
T3
The effect of tri-iodothyronine (T3) on protein turnover and metabolic rate.
The effect of tri-iodothyronine (T3) on protein t... [Int J Obes. 1985] - PubMed - NCBI
Wolman SI, Sheppard H, Fern M, Waterlow JC.
Abstract
Obese patients who had an unusually slow weight loss on a restricted energy intake (2 MJ/d) were treated for approximately two weeks with small doses of T3 (20 micrograms three times daily). At the beginning and end of treatment whole body protein turnover was measured with a single dose of 15N-glycine and both ammonia and urea as end-products. T3 increased the rate of weight loss, with a significant increase in urinary nitrogen excretion. There were small increases in basal metabolic rate and protein turnover, which were not significant. It is concluded that the extra weight loss produced by T3 was at the expense of lean body mass and not of fat.
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T3
The effects of triiodothyronine on energy expenditure, nitrogen balance and rates of weight and fat loss in obese patients during prolonged caloric restriction.
The effects of triiodothyronine on energy expendi... [Int J Obes. 1985] - PubMed - NCBI
Abraham RR, Densem JW, Davies P, Davie MW, Wynn V.
Abstract
We studied ten obese patients on prolonged caloric restriction by metabolic balance techniques two weeks before and two weeks after the start of treatment with triiodothyronine (T3) (0.36-1.01 micrograms/kg/d)[36-100mcg for a 100kg man]. The rate of weight, nitrogen and fat loss calculated from metabolic balance increased during T3 therapy and these effects were maximal in the second week of treatment. In seven patients studied continuously for four weeks on T3 therapy, the rates of weight and fat loss during the fourth week of treatment were not significantly different from pretreatment values while nitrogen loss was still significantly greater. The increase in nitrogen loss, studied after the period of adaptation to caloric restriction, implies that prolonged treatment with T3 can result in significant losses of lean tissue in addition to that resulting from caloric restriction alone. Mean weight loss increased by 92 g/d during T3 therapy. T3 significantly increased the metabolic rate as measured by two other independent measures: the resting energy expenditure (REE), measured by indirect calorimetry (fourteen patients), and the sleeping heart rate (six patients).
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T4
Effects of thyroxine on protein turnover in rat skeletal muscle
Effects of thyroxine on protein turnover in rat skeletal muscle
KE Flaim, JB Li, and LS Jefferson
Abstract
The effects of thyroxine (T4) on protein turnover in skeletal muscle were studied using normal, thyroidectomized (thyrex), and hypophysectomized (hypox) rats. Thyrex rats had a depressed growth rate that was accompanied by 50% reductions in the level of RNA and the rate of protein synthesis in gastrocnemius muscle, as determined in the perfused hemicorpus. Protein synthetic efficiency (protein synthesis per unit RNA) was decreased by 18%. Daily treatment of thyrex rats with T4 at different dose levels for up to 16 days led to improved growth rates, elevated RNA concentrations, and increased protein synthesis rates. The primary effect of T4 was to increase the protein synthetic capacity of muscle. Protein degradation, determined in the perfused hemicorpus, and activity of a lysosomal protease, determined in unperfused muscle, were reduced in the thyrex condition. Treatment of thyrex rats with T4 increased protein degradative rates, but not protease activity. Hypox rats, which also exhibited depressed skeletal muscle protein synthesis, responded to T4 and combined T4 and growth hormone with marked improvements in protein synthesis.
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T4vsT3
Comparison of the Effects of Thyroxine and Triiodothyronine on Protein Turnover and Apoptosis in Primary Chick Muscle Cell Cultures
ScienceDirect.com - Biochemical and Biophysical Research Communications - Comparison of the Effects of Thyroxine and Triiodothyronine on Protein Turnover and Apoptosis in Primary Chick Muscle Cell Cultures
Abstract
Primary chick muscle cells were treated with physiological level of thyroxine (T4) or triiodothyronine (T3) to examine the effects of the hormones on growth, protein turnover, and apoptosis of the cells. Creatine kinase activity, as an index of differentiation, was increased by both T4and T3.Even when the conversion from T4to T3was blocked by iopanoic acid, T4increased creatine kinase activity. The rate of protein degradation estimated from [3H] tyrosine release was increased by T3but not by T4. DNA cleavage and fragmentation, as indices of apoptosis, were induced by T3but not by T4. These results show that T4stimulates cell differentiation but not protein degradation and apoptosis in primary chick muscle cells, while all events are stimulated by T3.
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Good info sworder but your studies were done on higher doses of t3 which I specifically stated that I was talking about a low dose like 25mcg. We're also talking about taking it on the most potent aas there is pretty much which is suppressive to the thyroid. Its basically just kicking your metabolism up to where it should be and your not losing shit for muscle on tren unless your diet is horrible. Yes, of course t3 is catabolic, especially at higher doses but I was specifically talking about a low replacement dose while on anabolic steroids which completely changes the scenario.
 
Pretty much all drugs will exhibit effects in dose dependent manner, cycling is all about personal preference. Go ahead and try it! Some like t3, some do not. In the end, you have to find what works for you. If you don't notice much from t3, try t4 next go!
 
Sworder said:
Pretty much all drugs will exhibit effects in dose dependent manner, cycling is all about personal preference. Go ahead and try it! Some like t3, some do not. In the end, you have to find what works for you. If you don't notice much from t3, try t4 next go!
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haha this is prob my last cycle until im done with grad school. Imma keep the 40mcg until prob week 4 and then drop to normal replacement dose, which should'nt effect me at all :).
 
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