When on take 40mg about 1 hour before you go to bed.
When off take 20mg - Don't expect any results for 2 months.
Cholesterol is produce mainly at night so its best to take it then.
Take 120mg Cq10 with it as well as it lowers the amount of it in your body.
I can't recommend the stuff enough, it doubled my HDL in 6 months, just don't use that stuff made by source naturals....didn't do a thing.