Gyno....nothing i know of. Estrogen......man there's lots of stuff you can take to reduce that...6-oxo, ATD, rebound-XT, Restore, just go to any decent online supp site and type in Anti-e and you should get the results you're looking 4. the above mentioned are not vitamins but if you're "on" and want to reduce "E" then do what you have to. What kind of symptoms are you experiencing anyway?