What steps should I take if I crashed my E2 using anastrozole? I'm experiencing most of the symptoms. Blood work on 3/4/14 I felt normal and E2 was 29, which was prior to trt. Fast forward to 5/19/14 blood for e2 is <20 and I'm feeling the terrible side effects. Primarly, I have lost my libido and morning wood. It feels completely dead down there. My t levels as of 5/19 remain excellent.