lol man .. it starts from day 1 , 2 weeks in my test e cycle and my bodies starting to change and lifts are going up, think about it , ur first pin gives ur approx. 32 mg of test, from a 250mg/ml 1 cc shot , that's 3 times the amount of test a natural body builder has, by week 2 , ur in the 50s , and week 3/4 in the 80s...