when my estro was high,i mean out the roof,i felt like shit,no energy,no libido,didnt give a shit about nothing etc and all other things thats been mentioned,but i never had sore nipples,just bloat,and my endo didnt believe in a.i.'s...he said"under clinical doses of trt,estrogen levels and water retention is NEVER a problem,plus he never checked estro levels,said his practice didnt do them,so i proved him wrong and got my own estro test done,and i was right,and he got pissed,and called me and lowered my testosterone replacement therapy (TRT) dose to 100mg every 3weeks and he had me on 300mg/week..so i just told him to fuck off and i let my GP start taking care of my testosterone replacement therapy (TRT) protocol until i have my new endo appt in october...sorry for the rant brother