My testosterone replacement therapy (TRT) has suddenly lost it's effect

One inch needle is fine unless you have A LOT of fat where you are injecting.

Glory Days.

Tried to paste some pics here?


I am a little chubby as far as cinching my belt or getting any sort of Vee shape back, but not fat yet.

30mg e3d feels right. I'll get tested again mid March and get back.

I had the flu am just getting to where I'm not coughing up junk.

unka
 
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You might be a candidate for subcutaneous injections with a slin pin. look around the site, there should be info somewhere.
 
Your dose is low, the anxiety goes away after the first week if you ride it out, blood testing is eventual in the first few months. 150mg a week is a good start

HEY! I was taking 1.5 on my 1-Mil syringe e3days. Went to 2.5 e5d last week. That really woke me up for 2 days. My T level is around 412 last week. I'm going to as if I can go to 2.5 e4d. That would be about 375 mil p.m. versus the original 200 per mo. No anxiety at all in fact a feeling of well being. As long as my PSA? numbers stay low the Dr. should be ok with that.

Yes: It seems my Thyroid testosterone dropped off after a while and upping the dose is the ticket.

150 ml a week would be 600 ml p.m. Holy Smoke - is that a fairly common dose?


thx
Unka
 
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Dave,
At least one guy is pinning 250mg every week and another is doing 200mg per week ...so yes, plenty of guys are doing 150mg per week and more.

If your test mixture is the common 200mg per mL then I think you mean you did .15mL e3days which
200 x .15 = 30mg = 70mg per week

and then you took .25mL e5days last week that still averages 10mg per day but you got a bigger injection and felt better the first two days after you injected the .25mL.

Seems like you might need a bit more test...why not try .25mL every 3.5 days, which would equal 100 per week or even try .30mL every 3.5 days, which would equal 120mg per week and see how you feel.
 
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Dave,
At least one guy is pinning 250mg every week and another is doing 200mg per week ...so yes, plenty of guys are doing 150mg per week and more.

If your test mixture is the common 200mg per mL then I think you mean you did .15mL e3days which
200 x .15 = 30mg = 70mg per week

and then you took .25mL e5days last week that still averages 10mg per day but you got a bigger injection and felt better the first two days after you injected the .25mL.

Seems like you might need a bit more test...why not try .25mL every 3.5 days, which would equal 100 per week or even try .30mL every 3.5 days, which would equal 120mg per week and see how you feel.

I was doing about 1 vial e wk and 1/2
Yes - I think you are right as this dosage [.25 e3d?] [or as I look at my one Ml Syringe divided into 10 sections - I figure .5 per day -so it was 1.5 every 3d then just went to 2.5 e3day] has got me able to keep my HR around 140 for 40 min [I'm almost 61] on the ski machine - getting back to lifting and then feeling like I WANT to go out and set a [personal] World Record on my two mile run/walk. That's a lot better than just going thru the motions. But that is 5.0 every 6d (I think the Dr said CC"s are applicable to the 1 Ml syringe's 10 sections. So that puts me at almost 600 per. mo. Correct? Naw that can't be right. And is this a test therapy dose?? My test results as of June 10-13 were

Henatocrit................. 48% - - - 42-52 acceptable

Testosterone, Total and Free

Sex Hormone Binding Globulin......36nmo/l - - - 11-88 acceptable

Testosterone, Total ................... 430 ng/dl - - - 300-700 acceptable


Free Testosterone.................. 90.3 pg/dl - - 47-244 acceptable

Testosterone, % Free................ 2.1% - - - - - 1.6 - 2.9 acceptable

Albumin................................... 3.7 g/dl- - - - 3.5 - 5.0 acceptable

PSA 2.21 ng/ml Normal but up from - - - 1.7, - - 4 mo ago.
 
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Just talk about how many milligrams of test you are taking per week. That is a whole lot easier to follow than talking about it in terms of volume.
 
150 ml a week would be 600 ml p.m. Holy Smoke - is that a fairly common dose?


thx
Unka

Dave, I am on 150mg prescribed. My urologist started me on 200mg every two weeks which was a "rollercoaster on steroids," if you will. Then 200mg every 10 days. Better but still too much fluctuation. The 150mg per week seems perfect. I do not detect any real boom or bust between injection. No Aromatase inhibitor (AI), HCG or anything else. Doing real well on that dose and schedule. By the way you got 4 years on me.
Good luck.
 
A big factor that cannot be assessed by blood work is the sensitivity of the testosterone receptors in the cells.
I'd like to know more of what effects does using TRT do to the T receptors over time and to males who "cycle" and then go back to Natural T levels.
 
Just talk about how many milligrams of test you are taking per week. That is a whole lot easier to follow than talking about it in terms of volume.

:hahano: I - the Dr. Pharmiscist and Nurse can't seem to convert the info on the one ml syringe.

The 1 Ml Syringe is dvided into sections of 10. So I am now taking

.25Ml e3d -[instead of .15Ml e3d] which converts to - - - - -
.5Ml, or - - -1/2 the one Ml syringe e6days

Which is .505 e7days.

Times 4 which = 2.20 Ml in a month. ....??


If this is wrong please give me the conversion formula. I am sorry to bring this info to you in an improper format. I know it's irritating to those in the know.

Maybe I was under doseing due to bad math before?
 
:hahano: I - the Dr. Pharmiscist and Nurse can't seem to convert the info on the one ml syringe.

The 1 Ml Syringe is dvided into sections of 10. So I am now taking

.25Ml e3d -[instead of .15Ml e3d] which converts to - - - - -
.5Ml, or - - -1/2 the one Ml syringe e6days

Which is .505 e7days.

Times 4 which = 2.20 Ml in a month. ....??


If this is wrong please give me the conversion formula. I am sorry to bring this info to you in an improper format. I know it's irritating to those in the know.

Maybe I was under doseing due to bad math before?

Okay, first off testosterone is categorized by it's concentration per volume. The most commonly seen concentration in the US would be 200mg/mL, which in your case of .505mL E7D would be about 100mg/wk. I don't know why your doctor is having you do this with insulin syringes as they are measured in IU's or International Units which correspond to how insulin is measured. Many men can and do inject with insulin syringes, but unless you're comfortable with backloading them (removing the plunger and using another syringe to fill it), it's a hassle.

I recommend you pick up 3mL syringes with a 25g 1" needle and 18-21g needles separately. You would use the 18-21g needle to draw up the testosterone from the vial and then replace it with the 25g needle to inject. 3mL barrels will be clearly marked and make it much easier to identify how much you are drawing/injecting. If your script is for 100mg/wk, you just draw up .25mL E3D and inject (or .5mL E7D whichever you prefer).

Hope this helps. :)
 
Dave, I am on 150mg prescribed. My urologist started me on 200mg every two weeks which was a "rollercoaster on steroids," if you will. Then 200mg every 10 days. Better but still too much fluctuation. The 150mg per week seems perfect. I do not detect any real boom or bust between injection. No Aromatase inhibitor (AI), HCG or anything else. Doing real well on that dose and schedule. By the way you got 4 years on me.
Good luck.

How long have you been on this protocol?
Please post blood work.
How old are you?
 
I was doing about 1 vial e wk and 1/2
Yes - I think you are right as this dosage [.25 e3d?] [or as I look at my one Ml Syringe divided into 10 sections - I figure .5 per day -so it was 1.5 every 3d then just went to 2.5 e3day] has got me able to keep my HR around 140 for 40 min [I'm almost 61] on the ski machine - getting back to lifting and then feeling like I WANT to go out and set a [personal] World Record on my two mile run/walk. That's a lot better than just going thru the motions. But that is 5.0 every 6d (I think the Dr said CC"s are applicable to the 1 Ml syringe's 10 sections. So that puts me at almost 600 per. mo. Correct? Naw that can't be right. And is this a test therapy dose?? My test results as of June 10-13 were

Henatocrit................. 48% - - - 42-52 acceptable

Testosterone, Total and Free

Sex Hormone Binding Globulin......36nmo/l - - - 11-88 acceptable

Testosterone, Total ................... 430 ng/dl - - - 300-700 acceptable


Free Testosterone.................. 90.3 pg/dl - - 47-244 acceptable

Testosterone, % Free................ 2.1% - - - - - 1.6 - 2.9 acceptable

Albumin................................... 3.7 g/dl- - - - 3.5 - 5.0 acceptable

PSA 2.21 ng/ml Normal but up from - - - 1.7, - - 4 mo ago.

This blood work was done June 2013, correct?
You were on testosterone replacement therapy (TRT) for this test? you still on TRT?
how old are you?
how long have you been on TRT?

b.t.w. who made the "acceptable" approval beside each blood test? you or the doc?
Just want to see.
 
:hahano: I - the Dr. Pharmiscist and Nurse can't seem to convert the info on the one ml syringe.

The 1 Ml Syringe is dvided into sections of 10. So I am now taking

.25Ml e3d -[instead of .15Ml e3d] which converts to - - - - -
.5Ml, or - - -1/2 the one Ml syringe e6days

Which is .505 e7days.

Times 4 which = 2.20 Ml in a month. ....??


If this is wrong please give me the conversion formula. I am sorry to bring this info to you in an improper format. I know it's irritating to those in the know.

Maybe I was under doseing due to bad math before?

Yes, every 10 units on your insulin needle is .1mL or .1cc or 1/10th of a mL...100 units = 1mL........50 units = .5mL.......25 units = .25mL

You really should report in just milligrams (mg) before you drive some of us crazy ;) but I'll play, I'm that bored.......

Your math has an error and if we keep working at it, it should become easier to figure out so you are getting a good treatment.

.25Ml e3d -[instead of .15Ml e3d] which converts to - - - - -
.5Ml, or - - -1/2 the one Ml syringe e6days

Yes, this ^^^^^^ is correct.

Which is .505 e7days.

This ^^^^^ is NOT correct.

If you divide your .25mL e3d by 3 to get a daily dose....it is .25/3 = .08333333 or .08 and 1/3rd per day (:wink2: is that legal to mix decimals and fractions?)
So .08 and 1/3rd mL times 7 days = .583333mL per week (e7d)

Times 4 which = 2.20 Ml in a month

So therefore this ^^^^ is also wrong...it should be:

.583333mL x 4 = 2.3333mL every four weeks
 
Okay, first off testosterone is categorized by it's concentration per volume. The most commonly seen concentration in the US would be 200mg/mL, which in your case of .505mL E7D would be about 100mg/wk. I don't know why your doctor is having you do this with insulin syringes as they are measured in IU's or International Units which correspond to how insulin is measured. Many men can and do inject with insulin syringes, but unless you're comfortable with backloading them (removing the plunger and using another syringe to fill it), it's a hassle.

I recommend you pick up 3mL syringes with a 25g 1" needle and 18-21g needles separately. You would use the 18-21g needle to draw up the testosterone from the vial and then replace it with the 25g needle to inject. 3mL barrels will be clearly marked and make it much easier to identify how much you are drawing/injecting. If your script is for 100mg/wk, you just draw up .25mL E3D and inject (or .5mL E7D whichever you prefer).

Hope this helps. :)

This blood work was done June 2013, correct?
You were on testosterone replacement therapy (TRT) for this test? you still on TRT?
how old are you?
how long have you been on TRT?

b.t.w. who made the "acceptable" approval beside each blood test? you or the doc?
Just want to see.
I've said this on the first page posts. I am in early 60's. But I was the State champion in the 100 and 200 and beat the Japanese national champion in wrestling. I say this because I have been lifting and doing cardio to this day. I felt something was up when I wasn't able to recover from w/o's and w/o's actually hurt. I started test about one year ago. I'm one of those people who need to work out for a feeling of balance - even at my age.
I use a 1 inch needle on a one Ml Syringe because the 2 Ml at 1-1/2" needle is to imprecise for a .25Ml e3d dose. It is to hard pulling .25 Ml inaccurately [out of a 2Ml syringe] then trying to put .03 back in the vial. Testosterone leaking onto my hands.
I'm not on an insulin Syringe needle depth wise.

They send the test out to be done by a lab. I have no idea who came up with the norms. Don't really care to get into that minutia.

I had a distressing call back from the DR's Nurse. Not the Dr. who started me out on the test originally."
When I told her I really noticed an improvement in my vitality and ability to get a good workout - - - She replied
"Testosterone is a controlled substance, We want you to stay on .25Ml e5d instead of e3d. Or every 4d. "You are probably just getting high
I'm kind of bummed.
 
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"Testosterone is a controlled substance, "You are probably just getting high"

They are calling testosterone a drug people use to get high on..........hilarious!!!!!!!!!!!!


Your medical care is not safe in the hands of people with that level of intelligence....
 
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I've said this on the first page posts. I am in early 60's. But I was the State champion in the 100 and 200 and beat the Japanese national champion in wrestling. I say this because I have been lifting and doing cardio to this day. I felt something was up when I wasn't able to recover from w/o's and w/o's actually hurt. I started test about one year ago. I'm one of those people who need to work out for a feeling of balance - even at my age.
I use a 1 inch needle on a one Ml Syringe because the 2 Ml at 1-1/2" needle is to imprecise for a .25Ml e3d dose. It is to hard pulling .25 Ml inaccurately [out of a 2Ml syringe] then trying to put .03 back in the vial. I'm not on an insulin Syringe needle depth wise.

They sent the test out to be done by a lab. I have no idea who came up with the norms. Don't really care to get into that minutia.

I had a distressing call back from the DR's Nurse. Not the Dr. who started me out on the test originally."
When I told her I really noticed an improvement in my vitality and ability to get a good workout - - - She replied
I'm kind of bummed.

I am down in Medford, OR & I have been to 3 different doctors trying to find someone who knows what they are doing. I just recently found one that is willing to listen & try things that I bring up that make sense. This forum is awesome for learning. It amazes me that doctors that treat people for testosterone know nothing about looking at estrogen levels, they just look at you like you are crazy for asking such a thing. It's very frustrating to say the least. Good luck in your journey, I am at the begining of my journey as I am into my 4th week of pinning & it's a struggle to find the perfect balance in the hormone world.
 
.25Ml e3d -[instead of .15Ml e3d] which converts to - - - - -
.5Ml, or - - -1/2 the one Ml syringe e6days

I'm only using .25 Ml e4d [for sake of discussion]

One half of a 1Ml Syringe would = 50% of a 1Ml syringe. Or 50Ml e3d - That would be a hella lot of drug.

I need to take a class in Ml conversions. I swear I get a blank look on so many proffesionals and THEY disagree. My endocronologist had to go get a nurse - and she said she'd get back to us.
 
One half of a 1Ml syringe would = 50% of a 1Ml syringe. Or 50Ml e3d - That would be a hella lot of drug.

You need the decimal point, so it's .50mL

one half of 1mL............not 50 milliliters
 
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