New Member lost on what to do-plz help

[feeling aged]

Hello!
46 yr old and have had low T since 42. My T level prior to the plan below 212, below was a plan from a HRT clinic:

2x week 200mg cyp inj
2x week hcg inj
7x wk sermorelin
3x wk DHEA/Preg cream
1-2x wk 1mg Anastrozol
2x wk MIX b-12

My levels 3 wks after plan is:

Estradiol 5
Total Test 511
Sex hormone Bind Globulin 10
Free Test 35
IGF-1 219

I know my Estradiol level is low but other than that is this too much of that and not enough of this? Can I accomplish using clomid or am I subject to inj the rest of my life? I felt great while on even with sex drive but acne was a problem any ideas to prevent that? Supps to take after cycle? I have not been taking anything for about a year now and hate feeling this way. Any comments or suggestions would be appreciated.

 

[Megatron28]

I have moved this into the TRT forum.

 

[hiram1st]

Welcome to ology.

Read the TRT thread here:
http://www.steroidology.com/forum/a.../675497-ology-frequently-asked-questions.html

 

[Mprtz]

Can you double check your testosterone dose? It reads like 400mg per week, which is way more than TRT and should easily put your total testosterone over 2000.

You should definitely take less anastrozole... your E2 is much too low.

You didn't include lab ranges, but it looks like your SHBG is quite low and your free test is very high.

Considering the Sermorelin, your IGF-1 levels are not that impressive, do you know what they were before?

 

[Megatron28]

Checking blood work 3 weeks into TRT is too soon. Do you have additional blood work?

I am confused. Have you been off TRT for a whole year? If so, did you do an HPTA restart or did you just go cold turkey and live with hypogonadism?

Do you inject 200mg of test twice a week for a total of 400mg in a week? Is that how I should read what you wrote?

How much hCG do you take in a week? How often was it injected and at what dose?

You were taking too much arimidex when you had your blood work done. E2 that low will make you feel like total shit.

Clomid helps some guys, but they often don't feel the same on it as they do with injections. But it is an option if you were diagnosed with Secondary Hypogonadism. Given that you were taking hCG, I am guessing you were.

Supplements? I take vitamin D and cialis. I like to keep things simple. But that is just me.

Have you been donating blood to keep your hematocrit in check? I didn't see that listed in your blood work.

 

[Megatron28]

Mprtz is too fast.

 

[Megatron28]

Sermorelin is a growth hormone releasing hormone (GHRH). I don't see a growth hormone releasing peptide (GHRP) in your protocol. I am not super knowledgeable on peptides, but I thought they should be taken together in tandem to get the best effect. That may be why you are not getting any IGF-1 benefits. If your test dosage is really 400mg/week that alone should boost your IGF-1 up to that range if your pituitary is putting out growth hormone.

 

[cybrsage]

Yes, GHRH and GHRP should be taken together.

Problem w/ Using any GHRH alone
The problem with using a GHRH even the stronger analogs is that they are only highly effective when somatostatin is low (the GH inhibiting hormone). So if you unluckily administer in a trough (or when a GH pulse is not naturally occurring) you will add very little GH release. If however you luckily administer during a rising wave or GH pulse (somatostatin will not be active at this point) you will add to GH release.

Solution is GHRP + GHRH analog
The solution is simple and highly effective. You administer a GHRH analog with a GHRP. The GHRP creates a pulse of GH. It does this through several mechanisms. One mechanism is the reduction of somatostatin release from the hypothalamus, another is a reduction of somatostatin influence at the pituitary, still another is increased release of GHRH from the brain and finally GHRPs act on the same pituitary cells (somatotrophs) as do GHRHs but use a different mechanism to increase cAMP formation which will further cause GH release from somatotroph stores.

GHRH also has a way of reciprocally reinforcing GHRPs action.
The result is a synergistic GH release.
The GH is not additive it is synergistic. By that I mean:

If GHRH by itself will cause a GH release valued at 2
and GHRP itself will cause a GH release valued at 5
Together the GH is not 7 (5+2) it turns out to say 16!

A solid protocol
A solid protocol would be to use a GHRP + a GHRH analog pre-bed (to support the nightime pulse) and once or twice throughout the day.
For anti-aging, deep restful restorative sleep, the once at night dosing is all you need. For an adult aged 40+ it is enough to restore GH to youthful levels.
However for bodybuilding or fatloss or injury repair multiple dosings can be effective.
The GHRH analog can be used at 100mcg and as high as you want without problems.
The GHRP-2 can always be used at 100mcg w/o problems but a dose of 200mcg will probably be fine as well.
Again desensitization is something to keep an eye on particularly with the highest doses of GHRP-2 and all doses of Hexarelin.

So 100 - 200mcg of GHRP-2 + 100 - 500mcg+ of a GHRH analog taken together will be effective.
This may be dosed several times a day to be highly effective.

A solid approach is a bit more conservative at 100mcg of GHRP-2 + 100mcg of a GHRH analog dosed either once, twice, three or four times a day.
When dosing multiple times a day at least 3 hours should separate the administrations.
The difference is once a day dosing pre-bed will give a youthful restorative amount of GH while multiple dosing and or higher levels will give higher GH & IGF-1 levels when coupled with diet & exercise will lead to muscle gain & fatloss.

Dose w/o food
Administration should ideally be done on either an empty stomach or with only protein in the stomach. Fats & carbs blunt GH release. So administer the peptides and wait about 20 minutes (no more then 30 but no less then 15 minutes) to eat. AT that point the GH pulse has about hit the peak and you can eat what you want.

Datbtrue