oral steroids and liver toxicity - overstated?? Evidence based statement

[ryansm]

Yep, and why be cheap on health. Even if it is only a marginal improvement, it can do wonders in the long run. I run every cycle with Liver Juice and UDCA.

I would use the same combo of Liver Juice Liver Juice : Unparalleled Liver Protectionand UDCA/TUDCA if I still used methyls

 

[DADAWG]

Through time on these boards - a great number of discussions and a lot of fear has centered around the alledged liver toxicity of oral steroids. This study concludes that the liver toxicity might have been overstated:

Anabolic steroid-induced hepatotoxicity: is it overstated?

Dickerman RD, Pertusi RM, Zachariah NY, Dufour DR, McConathy WJ.


Source

The Department of Biomedical Science, University of North Texas Health Science Center, Fort Worth 76107-2699, USA.


Abstract

OBJECTIVE:

There have been numerous reports of hepatic dysfunction secondary to anabolic steroid use based on elevated levels of serum aminotransferases. This study was conducted to distinguish between serum aminotransaminase elevations secondary to intense resistance training and anabolic steroid-induced hepatotoxicity in elite bodybuilders.

DESIGN:

This was a case-control study of serum chemistry profiles from bodybuilders using and not using anabolic steroids with comparisons to a cohort of medical students and patients with hepatitis.

PARTICIPANTS:

The participants were bodybuilders taking self-directed regimens of anabolic steroids (n = 15) and bodybuilders not taking steroids (n = 10). Blood chemistry profiles from patients with viral hepatitis (n = 49) and exercising and nonexercising medical students (592) were used as controls.

MAIN OUTCOME MEASURES:

The focus in blood chemistry profiles was aspartate aminotransferase (AST), alanine aminotransferase (ALT), gamma-glutamyltranspeptidase (GGT), and creatine kinase (CK) levels.

RESULTS:

In both groups of bodybuilders, CK, AST, and ALT were elevated, whereas GGT remained in the normal range. In contrast, patients with hepatitis had elevations of all three enzymes: ALT, AST, and GGT. Creatine kinase (CK) was elevated in all exercising groups. Patients with hepatitis were the only group in which a correlation was found between aminotransferases and GGT.

CONCLUSION:

Prior reports of anabolic steroid-induced hepatotoxicity based on elevated aminotransferase levels may have been overstated, because no exercising subjects, including steroid users, demonstrated hepatic dysfunction based on GGT levels. Such reports may have misled the medical community to emphasize steroid-induced hepatotoxicity when interpreting elevated aminotransferase levels and disregard muscle damage. For these reasons, when evaluating hepatic function in cases of anabolic steroid therapy or abuse, CK and GGT levels should be considered in addition to ALT and AST levels as essential elements of the assessment.

i see your still a idiot who havent learned a damn thing lol. i suggest a cycle of dbol , halo , anadrol and superdrol at 100 mg each a day for 12 weeks , get back to us and let us know how that went for you.

 

[brother bundy]

OP you're one dumb fuck

 

[noway55]

Yes this article is a waste does not show shit bro sorry. They could've used Anavar (var) for all we know which is not very liver toxic. There's no date on it either. This is just a bad article to show kids on here. To say oral steroids are not liver toxic is just non sense. Do a study on yourself banging out some dbol only for four weeks at a high dose. See how your liver enzymes are doing.

agreed, this is one of those studies where you can't just read the results and conclusions from the abstract and extrapolate, you need to read the whole thing. honestly, from this abstract the study seems to be flawed and pretty much pointless

 

[HereToStudy]

agreed, this is one of those studies where you can't just read the results and conclusions from the abstract and extrapolate, you need to read the whole thing. honestly, from this abstract the study seems to be flawed and pretty much pointless

I am sure the full study gives more information, but without the full text who knows.

 

[josh223]

Children ages 8-16 male and female were often times prescribed oxymethylone(anadrol) for anemia. Usually they would stay on 50-300mg per day for 3-18 months. Never one issue with Liver came up. Doctors regularly tested bloods and they always came back clean. SOmetimes a little off but not enough to cause any serious issues.

I completely agree people act like oral steroids are poison lol. I take dbol every day during my bulking cycles. Sometimes only 20mg but I stay on dbol full length every bulker.

 

[RISE]

drinkin a beer and reading bout liver toxicity, great friday night.

 

[noway55]

Children ages 8-16 male and female were often times prescribed oxymethylone(anadrol) for anemia. Usually they would stay on 50-300mg per day for 3-18 months. Never one issue with Liver came up. Doctors regularly tested bloods and they always came back clean. SOmetimes a little off but not enough to cause any serious issues.

I completely agree people act like oral steroids are poison lol. I take dbol every day during my bulking cycles. Sometimes only 20mg but I stay on dbol full length every bulker.

Have you ever got your liver values checked afterwards?

 

[HereToStudy]

Have you ever got your liver values checked afterwards?

Yeah, if you LFTs do not move from extended dbol usage, I would venture to guess your dbol isn't legit.

 

[josh223]

Yes the only thing is my cholesterol goes up a little. And my LDL.

Since my cholesterol is pretty low while off cycle, it's still in the normal range.
Values return to normal after about 3-4 weeks of stop using.

Again I do not recommend someone with HIV or liver disease to use oral steroids. But for the normal person it is no worse then a glass of wine

 

[josh223]

I'm very sure it's legit. I get russian dbol pharmaceutical grade. Very high quality. Everyone I know who took it blew UP !!

 

[ryansm]

Children ages 8-16 male and female were often times prescribed oxymethylone(anadrol) for anemia. Usually they would stay on 50-300mg per day for 3-18 months. Never one issue with Liver came up. Doctors regularly tested bloods and they always came back clean. SOmetimes a little off but not enough to cause any serious issues.

I completely agree people act like oral steroids are poison lol. I take dbol every day during my bulking cycles. Sometimes only 20mg but I stay on dbol full length every bulker.

You do realize there is a substantial amount of reported highly elevated LFT's on several 17aa's and especially of late with SD and other designers being legally available until recently

 

[ryansm]

Yes the only thing is my cholesterol goes up a little. And my LDL.

Since my cholesterol is pretty low while off cycle, it's still in the normal range.
Values return to normal after about 3-4 weeks of stop using.

Again I do not recommend someone with HIV or liver disease to use oral steroids. But for the normal person it is no worse then a glass of wine

Well my own blood work history which is very extensive shows otherwise, again it is user dependent but 17aa methylated steroids are certainly liver toxic as well as toxic to the cardiovascular system

 

[MattPorter]

Iv'e got the constitution of a horse but I still load up on my Liver Juice before engaging in 17aa hormone cycles!

-Matt

 

[HereToStudy]

Iv'e got the constitution of a horse but I still load up on my Liver Juice before engaging in 17aa hormone cycles!

-Matt

It is such a cheap addition, that even if it only partially benefits your body, it should be added. You are putting your body through stress, why not help it out a bit!

 

[MattPorter]

It is such a cheap addition, that even if it only partially benefits your body, it should be added. You are putting your body through stress, why not help it out a bit!

Did you know its original product name was "Liver Steroid" ...but didn't like the negativity that 'steroid' brought to the table...

But this product is steroids for your liver....potent.

Liver "juice" (not juice because its liquid, but because its a juice cycle for your liver lol)

-Matt

 

[Big Hungry]

That info is total crap, u can google ph's and liver shutdown cases with bloodwork proving orals do damage if abused or used too long. Google superdrol and liver damage

 

[HereToStudy]

Did you know its original product name was "Liver Steroid" ...but didn't like the negativity that 'steroid' brought to the table...

But this product is steroids for your liver....potent.

Liver "juice" (not juice because its liquid, but because its a juice cycle for your liver lol)

-Matt

Haha, I actually never knew that. Just assumed it was juice due to liquid dosing.

That info is total crap, u can google ph's and liver shutdown cases with bloodwork proving orals do damage if abused or used too long. Google superdrol and liver damage

Exactly. It is like denying the skys color. It's accepted fact.

 

[MattPorter]

I would always play it safe and take orals VERY SERIOUSLY!

"but drinking is worse, but advil is worse but... but...."

Idiotic mentality -- take this stuff very serious and do not underestimate the potency.

Always minimize orals and when you do --- take the necessary measures -- NAC, Liver Juice, tucda etc..

-Matt

 

[SquadLeader]

Oral anabolic steroids liver toxicity is overrated. Although it isn't anything to take lightly their is a general fear instilled in people. Its always best to be on the safe side and thats liver toxicity is spoke of.