I love mine; leg fatigue seems to be diminished. I'm someone who has problems with shin splits etc., (typical big guy running problems). I've had them about two weeks, and I have prob 8 miles or so on them. For me, the real test of a shoe comes in how long they last--I'm 225lbs so I beat the crap out of shoes.
Also, the Reebok "Ree-tones" felt pretty good when I tried them on, would interested to see a review on them.