Restarting from being on testosterone replacement therapy (TRT) for a year!

30west

New member
Restarting from being on TRT for a year!

I'm 36 years old and have been on testosterone replacement therapy (TRT) for a year now. I was on the testosterone pellets for the past year and my wife and i decide we wanted another baby so I have stopped my testosterone replacement therapy (TRT) had my levels checked 2 weeks ago and test was 670. Down from my 1100's. Dr has started me on Human Chorionic Gonadotropin (HCG) 500iu 2x week for a month and wants me to have sperm check and see where i'm at. He said it will probably take 2 months worth of HCG. I have been lurking awhile and decided to finally post since I'm going through a restart, maybe my journey will have some useful info for others. I will be updating this as I go. Had my first shot of Human Chorionic Gonadotropin (HCG) in the quad yesterday, Dr gave it to me and gave me 7 preloaded injections to take home and do them myself. The only difference so far is my libido is back or atleast I think so....might just be my mind.

Test levels before testosterone replacement therapy (TRT) was in the 400's
 
Why did you come off testosterone replacement therapy (TRT)? My girlfriend got pregnant pretty fast and I've been on testosterone replacement therapy (TRT) dose for years (I'm 36) plus taking Human Chorionic Gonadotropin (HCG) at 250iu x 3 times / week

HCG is normally taken SubQ.

If I was going to come off testosterone replacement therapy (TRT) I'd probably just run basic post cycle therapy (pct). i.e. a blast of Human Chorionic Gonadotropin (HCG) for 10 days after my last shot of test, then a few days of nothing, then clomid and nolva for 6 weeks with an AI.

Good luck!
 
I'm coming off testosterone replacement therapy (TRT) because I was not taking Human Chorionic Gonadotropin (HCG) during my treatment. Human Chorionic Gonadotropin (HCG) can be administered either way, I don't think one way is better than the other. Does anybody think I should add nolvadex with the Human Chorionic Gonadotropin (HCG)? Or just follow what the Dr has prescribed me ?
 
id say add clomid and nolva... but thats just me.... im sure others will pipe in with their suggestions... if u search on here for a past member named : cashout

he had an awesome restart program that helped him and a few others restart and that was after being on testosterone replacement therapy (TRT) for a few years...
 
id say add clomid and nolva... but thats just me.... im sure others will pipe in with their suggestions... if u search on here for a past member named : cashout

he had an awesome restart program that helped him and a few others restart and that was after being on testosterone replacement therapy (TRT) for a few years...

Isn't there something about not using clomid, Human Chorionic Gonadotropin (HCG) and nolva all at the same time? Or two of them at the same time? Where's Det Oak when you need him?
 
Took my second injection of Human Chorionic Gonadotropin (HCG) today, feel no different down there yet, had good energy yesterday and today at gym. Libido pretty high!
 
Another shot of Human Chorionic Gonadotropin (HCG) today, feeling pretty good so far no side effects, felt like my nuts were aching a little yesterday not sure if it was mental or not lol.
 
My libido is threw the roof, I'm thinking the Human Chorionic Gonadotropin (HCG) has raised my test levels. Not carrying and water weight tho, looking nice and vascular!
 
My libido is threw the roof, I'm thinking the Human Chorionic Gonadotropin (HCG) has raised my test levels. Not carrying and water weight tho, looking nice and vascular!

The big question is where are your test levels at when you are done taking hcg. How much longer are you going to run Human Chorionic Gonadotropin (HCG) for in your restart?
 
I'm 36 years old and have been on testosterone replacement therapy (TRT) for a year now. I was on the testosterone pellets for the past year and my wife and i decide we wanted another baby so I have stopped my testosterone replacement therapy (TRT) had my levels checked 2 weeks ago and test was 670. Down from my 1100's. Dr has started me on Human Chorionic Gonadotropin (HCG) 500iu 2x week for a month and wants me to have sperm check and see where i'm at. He said it will probably take 2 months worth of HCG. I have been lurking awhile and decided to finally post since I'm going through a restart, maybe my journey will have some useful info for others. I will be updating this as I go. Had my first shot of Human Chorionic Gonadotropin (HCG) in the quad yesterday, Dr gave it to me and gave me 7 preloaded injections to take home and do them myself. The only difference so far is my libido is back or atleast I think so....might just be my mind.

Test levels before testosterone replacement therapy (TRT) was in the 400's
I dont think you should have stopped testosterone replacement therapy (TRT), you should have just added some Human Chorionic Gonadotropin (HCG) for a few weeks along with possibly low dos eclomid for a few weeks and at around week3-4 start trying to have kid...
not healthy to be off Hormone Replacement Therapy (HRT) if you need it.

good luck !
 
Yes, Human Chorionic Gonadotropin (HCG) should be ran alone. Run it in a blast phase before starting PCT with clomid and nolva.

you are wrong, this guy is on TRT! and trying to have kids, NOT the avrg joe comming off cycle. if that were the case then yes run Human Chorionic Gonadotropin (HCG), THEN post cycle therapy (pct).
for HIS reason I rec Human Chorionic Gonadotropin (HCG) AND clomid, because he is going back to testosterone replacement therapy (TRT) again because he needs it, his goal is kids, not long term recovery,...
 
I'm coming off testosterone replacement therapy (TRT) because I was not taking Human Chorionic Gonadotropin (HCG) during my treatment. Human Chorionic Gonadotropin (HCG) can be administered either way, I don't think one way is better than the other. Does anybody think I should add nolvadex with the Human Chorionic Gonadotropin (HCG)? Or just follow what the Dr has prescribed me ?

I understand that, but why did you not just add Human Chorionic Gonadotropin (HCG) TO your treatment? thats my point...

I rec testosterone replacement therapy (TRT), Human Chorionic Gonadotropin (HCG) and some clomid for your goal..
 
Isn't there something about not using clomid, Human Chorionic Gonadotropin (HCG) and nolva all at the same time? Or two of them at the same time? Where's Det Oak when you need him?

You rang??? :)

You are correct, it is not the best idea to take Human Chorionic Gonadotropin (HCG) with a SERM. Human Chorionic Gonadotropin (HCG) is suppressive to the HPGA contrary to popular belief. It only allows for partial function. Just like when taking testosterone, Human Chorionic Gonadotropin (HCG) will be interpreted as LH by the hypothalamus and slow down LH production, which is partially what SERM's stimulate.

Now I did run across a new study recently where they used Human Chorionic Gonadotropin (HCG), HMG and Clomid together and they did treat azoospermia better than previous protocols. Sooooooo......... On paper it does not make sense, but it is possible the combo could help, I don't know. I have never done it that way.

Optimization of spermatogenesis-regulating hormones in patients with non-obstructive azoospermia and its impact on sperm retrieval: a multicentre study.
Hussein A, Ozgok Y, Ross L, Rao P, Niederberger C.
Source
Minia Infertility Research and Treatment Unit, El-Minia University, El-Minia, Egypt. alaymanh@hotmail.com
Abstract
Study Type - Therapy (outcomes) Level of Evidence 2a What's known on the subject? and What does the study add? Clomiphene citrate, hCG and human menopausal gonadotropin (hMG) are widely used in treatment of oligospermia, because they increase FSH and testosterone which are essential for spermatogenesis. Finding a sperm in non-obstructive azoospermia for intracytoplasmic sperm injection is a challenge and much effort is required to reach the optimum method of sperm retrieval. The study shows that a new protocol of clomiphene citrate, hCG and hMG in the treatment of non-obstructive azoospermia achieves an increase in the levels of FSH, LH and total testosterone to the target levels that we set. Our target level of FSH was 1.5 times its initial level and for serum testosterone it was 600-800 ng/dL. Using our described medical treatment protocol in cases of non-obstructive azoospermia, sperm may be found in patients' ejaculate (~11%) and if they remain azoospermic they will have a greater likelihood of sperms being obtained in testicular sperm extraction.
OBJECTIVE:
To evaluate the effect of optimizing serum level of follicle-stimulating hormone (FSH), luteinizing hormone (LH) and testosterone on sperm retrieval for intracytoplasmic sperm injection.
PATIENTS AND METHODS:
A total of 612 patients with non-obstructive azoospermia were evaluated with routine history, physical examination and hormonal assessment. Of these, 116 patients underwent microsurgical (micro)-testicular sperm extraction (TESE) without any medical treatment and formed the control group and the remaining 496 patients were administered clomiphene citrate in a titrated dose. Patients were classified into four groups according to their response to clomiphene citrate. Group 1: patients with an obvious increase in FSH and total testosterone (n = 372). Group 2: patients showing an increase in FSH with no or little increase in LH and total testosterone (n = 62). For these patients we continued with clomiphene citrate and added human chorionic gonadotrophin (hCG). Group 3: patients with no increase in the levels of the three hormones (n = 46). Group 4: included patients with continuously decreasing serum testosterone levels in response to the increasing dose of clomiphene citrate (n = 16). Accordingly, patients in groups 3 and 4 discontinued clomiphene citrate and started hCG and human menopausal gonadotropin (hMG). Semen analyses were performed periodically and, in patients who remained azoospermic, micro-TESE was performed.
RESULTS:
Sperm were noted in 54 patients (10.9%) in semen analysis after treatment in all groups (with no significant difference) at a mean (sd) concentration of 2.3 (4.1) million/mL. For the 442 patients who remained azoospermic after treatment, successful sperm retrieval was significantly higher (57%) compared with the control group (33.6%).
CONCLUSION:
For patients with non-obstructive azoospermia, clomiphene citrate, hCG and hMG administration, leading to an increased level of FSH and total testosterone, results in an increased rate of sperm in the ejaculate and increased likelihood of successful micro-TESE.

Optimization of spermatogenesis-regulating hormones ... [BJU Int. 2013] - PubMed - NCBI

The problem I have with the study is they gave them clomid first and then added Human Chorionic Gonadotropin (HCG) and HMG. So could the clomid have been pointless at that stage? Very possible IMO.
 
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I understand that, but why did you not just add Human Chorionic Gonadotropin (HCG) TO your treatment? thats my point...

I rec testosterone replacement therapy (TRT), Human Chorionic Gonadotropin (HCG) and some clomid for your goal..

That's what I thought but Dr told me I'd have to come off testosterone replacement therapy (TRT) to get my sperm count back up. I did order some clomid to add to my Human Chorionic Gonadotropin (HCG) protocol, I'm down about 4 pounds since I started the HCG. Just looks like I'm losing water weight. Did another 500iu's yesterday in my quad.....Still horny as a teenager! lol
 
Hey guys,
I'm in a similar situation as 30west. I'm 35 and just came of testosterone replacement therapy (TRT) (Androgel 5g/daily) so I can have a second kid. Came off 7.5 g of Androgel about 1.5 years ago to have my first and obviously it worked. I did it cold turkey though - what a terrible experience. Hated my life and had no interest in sex, which is NOT good when you're trying to conceive.

My doc refused to put me on Human Chorionic Gonadotropin (HCG) or Clomid. He told me not believe what I read on the internet because it doesn't work. He's an idiot. I don't think I was on enough Androgel in the first place because my levels never surpassed 500.

Anyway, I've ordered some Human Chorionic Gonadotropin (HCG) and Clomid hoping that one or both will help me recover faster. From what I've read so far, I should be dosing with the Human Chorionic Gonadotropin (HCG) first and then supplementing with Clomid. Does that make sense?

I admit, I'm a little nervous about the Human Chorionic Gonadotropin (HCG) and especially giving myself a needle. Any help/recommendations would be greatly appreciated.
 
The big question is where are your test levels at when you are done taking hcg. How much longer are you going to run Human Chorionic Gonadotropin (HCG) for in your restart?

Dr said to run Human Chorionic Gonadotropin (HCG) 2x a week of 500iu's for a month and have sperm test and see where we are at before he prescribes another month of HCG.
 
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