Sweating Profusely with GHRP-2 and Mod-GRF(1-29)

Megatron28

Megatron28

Moderator
I decided to give GH peptides a try. I tried GHRP-2 and Mod-GRF(1-29) for the first time last night before bed at 100mcg each. Within about 5 minutes I was drenched with sweat and I felt weak and "off". First thing that crossed my mind was hypoglycemia so I ate some carbs. It took about 30 minutes before I started feeling better. I then I felt really hungry! I have read that other people have experienced the sweating and weird feelings too -- for example in the following linked thread. See the first few posts.


http://www.steroidology.com/forum/peptide-science/671217-my-ghrp2-mod-grf-1-29-log-2.html


I have been doing some reading trying to figure out what is causing this and understand if the problem persists with people. I have read lots of theories from the IGF-1 spike causing hypoglycemia, to ghrelin being released, to it being caused by hypergylcemia from the growth hormone pulse. And lots of other theories. I have ordered a blood glucose monitor so I can check for myself and see what is happening to my glucose -- if anything. I think I will hold off on administering another dose until I have it in hand. But I would like to understand what is going on and hear other guys' experiences. I would hate to take it before bedtime and fall asleep with hypo/hyperglycemia.
 
In for experiences too as I'm probably going to go this route if my HGH attempt bears no fruit.
 
I still have my Tren virginity intact. I have some Tren A but I haven't opened it up yet. I am saving myself for that special moment when the time is right.
 
I have read that moderate to heavy caffeine use, when combined with any form of GHRP, can cause daytime sleepiness and nighttime insomnia. While I have not read anything about sweats, I can see it being related if you are a heavy caffeine user.

They key for those with the problem was to cut out caffeine altogether. You could always give it a try.
 
cybrsage said:
I have read that moderate to heavy caffeine use, when combined with any form of GHRP, can cause daytime sleepiness and nighttime insomnia. While I have not read anything about sweats, I can see it being related if you are a heavy caffeine user.

They key for those with the problem was to cut out caffeine altogether. You could always give it a try.
Click to expand...

I have not had any caffeine for about 6 months.
 
I thought I would add in some other info in case it is relavent.

I am on a ketogenic (very low carb) diet. I am on TRT which is 100mg test cyp, 500iu hCG and .25mg arimidex every 3.5 days. Also taking .50mg of cabergoline every 3.5 days as it helps reduce appetite. 10mg cialis daily.
 
I found this, it talks about using insulin and a Mod GRF/GHRP-2, says it can easily cause blood glucose levels to crash. It is possible that the GRF/GHRP combo by itself does lower blood glucose levels, so if you are already very lose it might be enough to push you over the edge. You could always get a blood sugar monitor and test yourself before taking the combo and then a few minutes later, when you start to feel off. You will know for certain if that is the issue.

*WARNING ... something CAN happen when you dose Mod GRF (1-29)/GHRP-2 and then come back within say 40 minutes and dose again AND you use exogenous insulin.... what can happen? Years ago I tried this with maybe 8iu of humulin R and my blood glucose levels crashed. I was a mad experimenter at the time and I actually stopped to take readings as it fell to 29 mg/dL. It seemed like it took a lot of sugar just to get it back to 40.

The next day I was curious and I repeated the experiment and the exact same thing happened. I got the 29ng/ml reading and was so close to slipping into unconsciousness... very scary. Never figured out why but I have a post on it somewhere around... I was focusing on insulin receptor blockade... anyway the point is to be careful with scrunch dosing and insulin.
Click to expand...
Datbtrue
 
Sweating is a well known side effect of ghrp-2:

http://www.eje-online.org/content/157/1/19.full.pdf

I suspect the main cause would be cortisol related since your cortisol levels when dieting are going to be higher anyway and ghrp-2 may exacerbate the issue.
Higher cortisol leads to an increase in sweating plus water retention (not good if your dieting).

Higher ghrelin is an interesting theory and easy enough to disprove.
If your having more frequent bowl movements and/or feeling more hungry, then ghrelin may be the culprit. Ghrelin is well known as the main stomach hunger hormone and can increase gastrointestinal motility, which may increase sweating.

I suspect the severity of these sides are age dependent but regardless of the cause, I wouldn't continue with the ghrp-2 if it does indeed increase cortisol/ghrelin because neither is good for your dieting efforts :)
 
Mrrippedzilla said:
Sweating is a well known side effect of ghrp-2:

http://www.eje-online.org/content/157/1/19.full.pdf

I suspect the main cause would be cortisol related since your cortisol levels when dieting are going to be higher anyway and ghrp-2 may exacerbate the issue.
Higher cortisol leads to an increase in sweating plus water retention (not good if your dieting).

Higher ghrelin is an interesting theory and easy enough to disprove.
If your having more frequent bowl movements and/or feeling more hungry, then ghrelin may be the culprit. Ghrelin is well known as the main stomach hunger hormone and can increase gastrointestinal motility, which may increase sweating.

I suspect the severity of these sides are age dependent but regardless of the cause, I wouldn't continue with the ghrp-2 if it does indeed increase cortisol/ghrelin because neither is good for your dieting efforts :)
Click to expand...

Thanks Mr. RZ! I see I should have bounced this off you beforehand. So how about switching to Ipamorelin? Or would it be better to just wait until I am done dieting in your estimation? Or just forget the whole idea altogether and sell it to some kid looking to get swole? :)

I still may try it one more time when I get my glucose meter delivered in the mail just to see if it does affect blood sugar. Consider it taking one for the team.

P.S. Bowel movements were normal after my one dose.
 
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Need to know where you got your peptides from cuz my peptides are a huge let down. GHRP/CJC stack... Properly dosed and stuff. Did it for months, didn't feel or notice a thing. Maybe I didn't run it for a good amount of time... I ran it only 4 months. No hunger, no carpel tunnel, no nothing
 
Megatron28 said:
Thanks Mr. RZ! I see I should have bounced this off you beforehand. So how about switching to Ipamorelin? Or would it be better to just wait until I am done dieting in your estimation? Or just forget the whole idea altogether and sell it to some kid looking to get swole? :)

I still may try it one more time when I get my glucose meter delivered in the mail just to see if it does affect blood sugar. Consider it taking one for the team.

P.S. Bowel movements were normal after my one dose.
Click to expand...

Lol I'm not an expert on peptides by any means - just an area I'm interested in for future "experimentation" :)

Ipamorelin would certainly reduce the negative sides associated with ghrp-2, though they will still be present to some degree - its a better choice for you if the sides of ghrp-2 are still troublesome next time you try it.

Increasing GH obviously helps with fat loss but if sides such as appetite stimulation present themselves then I'd obviously recommend skipping it completely for now.
There is no point in aiding fat loss through higher GH (very much a secondary player in fat loss btw) if appetite skyrockets.
 
I did my follow up experiment this morning shortly after waking. First time using the peptides again since my first attempt.

I took 100mcg of each again. I felt a little weird a few minutes after, but not nearly like the first time. I got a little sweaty again, but nothing too bad.

I checked glucose before and after with my new meter. I was at 84 for baseline and about 20 minutes after injecting I was at 83. So glucose wasn't affected.

I don't have the extreme onset of hunger either.

I think I will continue trying it and see if things continue to be better. I will have to give it a try before bedtime again.

Thanks for your help guys. I will try to update this and let everyone know how it is going.
 
Ghrp2 never gave me crazy hungar like ghrp6. With the GHRP6 it's literally uncontrollable. I know peptides cause such a quick pulse that it rapidly increases blood flow to the skin, (which is why over time the skin looks better), it's kind of like a niacin flush. It even feels like a niacin flush and then you can sweat like a slave in a desert for a few minutes.
 
I'm currently on my 2nd run of Peptides. This time, from a different source. The first time I used it - was the same cycle - GHRP2 and CJC 1295...after my first pin I felt weak, tired, like i had no sugar or carbs or anything in me...i literally had to sit in my car and wait for it to pass...I couldn't drive...I was done.
Took about two hours for it to pass. Various feedback I got was everything from the saturation within the body to blood glucose. After a few more pins I didn't have the issue - maybe a bad batch. IDK...my peptide run actually worked pretty well...but not as good as the one I'm using at the moment.
 
I'm thinking maybe tapering up to try to avoid that. Maybe start at 50, 75, 100. I have ghrp2 and cjc1295. But haven't started yet.
 
Ipamorelin is def a better choice than ghrp2 when cutting and perhaps may be the best form of a ghrp for long term use anyway. It has a lower gh pulse per se but over time it actually would have a higher pulse than ghrp2 & 6 due to its lack of effect on GHIH. Also the aforementioned effects on cortisol as well as Prolactin.
Honestly I suspect the issue here is more the keto diet but moving forward for me my gh stack of choice will be Mod GRF and Ipam for what that is worth.
 
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