using antidepressants on a cycle

rickangle

New member
Anyone know of any concerns/side effects in using antidepressants while on a short 5week cycle of test e/d-bol
My friend is a little worried about it, for him it is first cycle and has been a long term daily user of antidepressants
feedback anyone please
 
im on anti anxiety med's it doesnt seem to really effect my cycles weakens my appitite but just gotta keep on eating
 
I hope the 5 weeks of TestE is the typo, if not 5 weeks isnt long enough 10 weeks at the minimum. The only concern might be is while he is on his confidence and self image and just general well being will most likely be boosted bc of the test and dbol, this might lead him to think he doesnt need his meds anymore then when he stops he hits the bottom, just make sure he keeps taking his meds.
 
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My workout partner takes anti-d's and cannot take dbol because it spawns really bad anxiety attacks, but he has no problems with taking test and said it actual improves his mood(just like it improves mine because I'm getting swole!).
 
my medication

Hello gorilla boy. I take a antianxiety drug called anafranil. I believe it is a derived from chlomipramine. I also take Zocor 10mg a day for cholesterol control. However, my recent cholesterol test have been good according to my doctor. Any other shared info is greatly apprecited. Peace.
 
Check out the contraindications... IM injections? what's that all about?

Under: "Interactions with Drugs and Other Substances"... female hormones (estrogens)?



http://www.whatmeds.com/meds/anafranil.html

Clomipramine
Brand name: Anafranil

Overview
Anafranil is a tricyclic antidepressant (TCA) and antiobsessional. Anafranil works by raising levels of norepinephrine (a neurotransmitter) to normal levels. This drug is used to reduce the anxiety and unpleasant thoughts that cause obsessive-compulsive behaviors such as repeating an ordinary task many times, and help such a patient lead a more normal lifestyle. It is also used to treat depression.

Anafranil’s effects may be felt in a few days, or four weeks or more, depending on the patient and the dosage.

Why is this drug prescribed?
Anafranil is used mainly to treat obsessions and compulsions in patients with Obsessive-Compulsive Disorder (OCD.)

Anafranil is also used to treat:

arm burning
endogenous depression
hair pulling syndromes
nail biting
panic attacks
phobias
pre-menstrual syndrome (PMS)
pain due to narcolepsy
arthritis, cancer, diabetic disease, herpes lesions, migraines, tension headaches, or tic douloureux
repetitive symptoms in autistic persons
Warnings and Precautions
Anafranil is not recommended for use in children under ten years old. Adolescents should receive smaller doses than the recommended adult dose.

Anafranil may cause seizures in patients with a history of seizures or other factors that make seizures more likely such as brain damage, alcoholism, and use of Anafranil with other drugs that lower the seizure threshold. Taking smaller doses may reduce the incidence of seizures.

Anafranil is not addictive. Suddenly discontinuing use of Anafranil may cause withdrawal, and dosage should be reduced gradually to minimize withdrawal symptoms.

For Pregnant or Nursing Mothers: Controlled studies have not been done in pregnant women, but there have been reports of newborns suffering from muscle spasms and heart, breathing, and urinary problems when their mothers had taken tricyclic antidepressants immediately before delivery. Animal studies show that some tricyclic antidepressants may have undesirable effects on a fetus. Tricyclic antidepressants pass into breast milk and are reported to cause drowsiness in nursing infants.

Anafranil may cause drowsiness or even sudden loss of consciousness. A patient should not drive or operate heavy machinery until the effects of Anafranil on that patient are known and do not present a danger to the patient or others.

Cardiovascular Effects: tachycardia (an abnormally high heart rate), and decreased blood pressure appeared in 20% of patients during clinical trials. Dosage should start low and increase gradually in patients with heart disease.

Contraindications
Anafranil should Not be used for people who have:

a history of hypersensitivity to Anafranil or to other tricyclic antidepressants
within 14 days been treated with a monoamine oxidase (MAO) inhibitor (very high fever, seizures, coma, and death have been reported in patients receiving such combinations)
had a recent myocardial infarction
an alcohol problem
asthma
blood disorders or disease
diabetes
difficulty passing urine or prostate trouble
narrow angle glaucoma
intramuscular injections
liver disease or stomach disease
an over active thyroid
Parkinson’s disease
schizophrenia - tricyclic antidepressants, including Anafranil, may cause a psychotic episode in patients with unrecognized schizophrenia.
seizures or convulsions
active bone marrow depression
heart disease - dosage should start low and increase
Adverse Reactions
Anafranil may cause the following adverse reactions:

dry mouth
constipation
nausea
indigestion
loss of appetite
sleepiness
tremor
dizziness
nervousness
muscle spasms
changed libido
ejaculatory failure
impotence
difficulty urinating
swelling of the testicles
fatigue
sweating
increased appetite
weight gain
blurred vision or eye pain
breast enlargement in both males and females
confusion
hallucinations
difficulty breathing
fainting spells
fever
irregular or fast, pounding heartbeat, palpitations
seizures or convulsions
stomach pain
tingling, pain, or numbness in the feet or hands
yellowing of the eyes or skin
photosensitivity and impaired ability to adapt to hot environments
Interactions with Drugs and Other Substances
Drugs or substances that may interact with Anafranil are:

MAO Inhibitors (within 14 days) — serious or even fatal interactions can occur when taken with Anafranil
alcohol - when taken with Anafranil can increase the intoxicating effects of alcohol and combination can depress brain function significantly; alcohol should be avoided completely
barbiturate medicines for inducing sleep or treating seizures (convulsions)
blood thinners
cimetidine and ranitidine
clonidine
diltiazem
female hormones (estrogens), including contraceptive or birth control pills
lithium
medicines for anxiety or sleeping problems, such as diazepam or temazepam
medicines for colds and breathing difficulties
medicines for hay fever and other allergies
medicines for mental problems and psychotic disturbances such as Prozac (fluoxetine), Luvox (fluvoxamine), Normodyne (labetalol), Ritalin (methylphenidate),
medicines for movement abnormalities as in Parkinson's disease, or for gastointestinal problems e.g. Zantac (ranitidine), Tagamet (cimetidine)
medicines that treat depression
seizure (convulsion) or epilepsy medicine
thyroid hormones
phenothiazines
Quinaglute (quinidine)
ACE inhibitors
Calan (verapamil)
smoking accelerates the elimination of this drug from the body and increases the dosage required
 
Tricyclic antidepressants like Anafranil/clomipramine can cause thrombocytopaenia - a reduction in the number of blood platelets. This may lead to a bleeding tendency- the caution about intramuscular injections is because you could get a big haematoma/bruise by combining sharp hurty things and platelets that don't make good clots easily.
 
blue_pill said:
Tricyclic antidepressants like Anafranil/clomipramine can cause thrombocytopaenia - a reduction in the number of blood platelets. This may lead to a bleeding tendency- the caution about intramuscular injections is because you could get a big haematoma/bruise by combining sharp hurty things and platelets that don't make good clots easily.

Great info. Thanks :)
 
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