Warning: Anadrol will kill you!
- Thread starter Mudge
- Start date
slobberknocker
pro powerlifter
It's true guys. I die every time I take drol.
Hootie
New member
I have personally experienced kidney pain on 50mg of anadrol a day. 150mg/day for over 7 months ????? what do these people look like after taking this much for so long? this must cause some damage otherwise we could be eating d/bols like breathmints? Sounds like bs to me.
Last edited:
sex on legs
Novice
claims. anadrol at 50mg/day for six weeks kills me. so at 150mg/d for 7 months is just ridiculous. obviously bullshit.
utryin to kill us? lol
utryin to kill us? lol
hhajdo
Community Veteran
AIDS. 2003 Mar 28;17(5):699-710. Related Articles, Links
Double-blind, randomized, placebo-controlled phase III trial of oxymetholone for the treatment of HIV wasting.
Hengge UR, Stocks K, Wiehler H, Faulkner S, Esser S, Lorenz C, Jentzen W, Hengge D, Goos M, Dudley RE, Ringham G.
STD-Unit, Department of Dermatology and Venerology, University of Essen, Germany. ulrich.hengge@uni-duesseldorf.de
BACKGROUND: Despite highly active antiretroviral therapy (HAART), chronic involuntary weight loss still remains a serious problem in the care of HIV patients. Various alterations in energy metabolism and endocrine regulation have been found to cause loss of lean body mass (LBM) and body cell mass (BCM). Previous studies in HIV-positive men undergoing androgen replacement therapy or treatment with recombinant growth hormone (rGH) have shown partial restoration of LBM, but these treatments have largely been ineffective in eugonadal individuals. STUDY DESIGN: Double-blind, randomized, placebo-controlled trial of 89 HIV-positive women and men with wasting assigned to the anabolic steroid oxymetholone [50 mg twice (BID) or three times daily (TID)] or placebo for 16 weeks followed by open-label treatment. STUDY ENDPOINTS: Body weight, bioimpedance measurements, quality of life parameters and appetite. RESULTS: Oxymetholone led to a significant weight gain of 3.0 +/- 0.5 and 3.5 +/- 0.7 kg in the TID and BID groups, respectively (P < 0.05 for each treatment versus placebo), whereas individuals in the placebo group gained an average of 1.0 +/- 0.7 kg. Body cell mass increased in the oxymetholone BID group (3.8 +/- 0.4 kg; P < 0.0001) and in the oxymetholone TID group (2.1 +/- 0.6 kg; P < 0.005), corresponding to 12.4 and 7.4% of baseline BCM, respectively. Significant improvements were noted in appetite and food intake, increased well-being and reduced weakness by self-examination. The most important adverse event was liver-associated toxicity. Overall, 35% of patients in the TID, 27% of patients in the BID oxymetholone group and no patients in the placebo group had a greater than five times baseline increase for alanine aminotransferase during the double-blind phase of the study. CONCLUSIONS: Oxymetholone can be considered an effective anabolic steroid in eugonadal male and female patients with AIDS-associated wasting. The BID (100 mg/day) regimen appeared to be equally effective as the TID (150 mg/day) regimen in terms of weight gain, LBM and BCM and was associated with less, but still significant liver toxicity.
Double-blind, randomized, placebo-controlled phase III trial of oxymetholone for the treatment of HIV wasting.
Hengge UR, Stocks K, Wiehler H, Faulkner S, Esser S, Lorenz C, Jentzen W, Hengge D, Goos M, Dudley RE, Ringham G.
STD-Unit, Department of Dermatology and Venerology, University of Essen, Germany. ulrich.hengge@uni-duesseldorf.de
BACKGROUND: Despite highly active antiretroviral therapy (HAART), chronic involuntary weight loss still remains a serious problem in the care of HIV patients. Various alterations in energy metabolism and endocrine regulation have been found to cause loss of lean body mass (LBM) and body cell mass (BCM). Previous studies in HIV-positive men undergoing androgen replacement therapy or treatment with recombinant growth hormone (rGH) have shown partial restoration of LBM, but these treatments have largely been ineffective in eugonadal individuals. STUDY DESIGN: Double-blind, randomized, placebo-controlled trial of 89 HIV-positive women and men with wasting assigned to the anabolic steroid oxymetholone [50 mg twice (BID) or three times daily (TID)] or placebo for 16 weeks followed by open-label treatment. STUDY ENDPOINTS: Body weight, bioimpedance measurements, quality of life parameters and appetite. RESULTS: Oxymetholone led to a significant weight gain of 3.0 +/- 0.5 and 3.5 +/- 0.7 kg in the TID and BID groups, respectively (P < 0.05 for each treatment versus placebo), whereas individuals in the placebo group gained an average of 1.0 +/- 0.7 kg. Body cell mass increased in the oxymetholone BID group (3.8 +/- 0.4 kg; P < 0.0001) and in the oxymetholone TID group (2.1 +/- 0.6 kg; P < 0.005), corresponding to 12.4 and 7.4% of baseline BCM, respectively. Significant improvements were noted in appetite and food intake, increased well-being and reduced weakness by self-examination. The most important adverse event was liver-associated toxicity. Overall, 35% of patients in the TID, 27% of patients in the BID oxymetholone group and no patients in the placebo group had a greater than five times baseline increase for alanine aminotransferase during the double-blind phase of the study. CONCLUSIONS: Oxymetholone can be considered an effective anabolic steroid in eugonadal male and female patients with AIDS-associated wasting. The BID (100 mg/day) regimen appeared to be equally effective as the TID (150 mg/day) regimen in terms of weight gain, LBM and BCM and was associated with less, but still significant liver toxicity.
slobberknocker
pro powerlifter
Do you actually have nerves in your kidneys that can send pain messages to your brain?
BiggieSwolls
Steelers = SuperBowl
Although I understand what the article/study is trying to get at, am I the only one who thinks that the statement about no significant problems with water retention at 150 mg/day is a bit out there?
BiggieSwolls
Steelers = SuperBowl
I hear you, but I personally really do not know of anyone who hasnt bloated up with Drol. Even the leanest of guys I know hold a pretty decent amount of water on drol, and none of them is taking 150 mg/day. We're talking 50-100 mg's/day
I guess its really how we interpret what "significant problems with water retention" really means. Does it mean that there was very little water retention or does it mean that no one was unable to tie their shoes because of the water retention?
But on the whole I do see and agree where the article is coming from. The flip side to it is that you know at least one guy is going to go out and start doing 150 mg/day of drol because he now thinks its good for him and wont have any negatave impact.
I guess its really how we interpret what "significant problems with water retention" really means. Does it mean that there was very little water retention or does it mean that no one was unable to tie their shoes because of the water retention?
But on the whole I do see and agree where the article is coming from. The flip side to it is that you know at least one guy is going to go out and start doing 150 mg/day of drol because he now thinks its good for him and wont have any negatave impact.
